Sentences with phrase «pure populations of cells»

The ability to make pure populations of these cells within days rather than the weeks or months previously required is a key step toward clinically useful regenerative medicine — potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.

According to the authors, future studies should aim to improve the efficiency of the approach to generate a pure population of cells that closely mimic adult Leydig cells.

«The ability to generate pure populations of these cell types is very important for any kind of clinically important regenerative medicine,» said Loh, «as well as to develop a basic road map of human embryonic development.

Not exact matches

Deng and his colleagues next induced the stem cells to develop into separate pure populations of astroglial cells and neurons.

The findings, published Aug. 31 in the journal Science Advances, could also lead to a simple, scalable and inexpensive way to manufacture a pure population of bone - building cells.

Although some teams have managed to produce nearly pure colonies of certain kinds of neural cells from ES cells, no one has managed to concoct a recipe that will direct the cells to become, say, a pure population of dopamine - producing neurons that could replace those missing in Parkinson's disease.

The result: tiny green spheres about half a millimeter across, «a population of pure, early lung cells,» says Hawkins.

«Those approaches take a long time, it is difficult to isolate a pure population, and the NPC - like cells are still transient,» says Zhongwei Li, a research associate in the Izpisua Belmonte lab and co-first author of the new paper.

Developing therapeutic cell populations from human ES cells will be far more demanding: cells will have to be stable, predictable, pure, have proven functionality, be nontumor - forming, and be «scalable» — capable of growing in very large numbers.

After this period of induction, keratinocytes derived from pluripotent stem cells were isolated and amplified to obtain a homogenous and pure population of keratinocytes presenting all the phenotypic characteristic of adult keratinocytes.

Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage.

Having a pure population of cardiac muscle cells is essential for avoiding tumor formation after transplantation, but has been technically challenging.

Functional and phenotypic differences of pure populations of stem cell - derived astrocytes and neuronal precursor cells.

This approach not only enables us to get highly pure populations of DA progenitor cells (> 90 %), but it also increases our final yield of transplantable cells > 40 times when compared to previous embryoid body protocols starting with the same number of cells.

This led researchers from the group of Joseph S. Anderson (University of California Davis, USA) to formulate a new strategy; the use of a combined anti-HIV and selection vector [5, 6] to enrich for modified HSPCs, to provide a pure and effective cell population for therapeutic purposes.

Sorting breast cancer cells using a new reporter construct allows the interrogation of a highly pure population of cancer stem cells and may allow for the discovery of new therapeutic targets

However, with few exceptions, the stem cell and regenerative medicine industry has remained inadequately capitalized to carry out large - scale clinical trials independently, and major pharmaceutical firms have tended to show more interest in the use of hiPSCs as a source of large, pure populations of specific somatic cells for use in drug compound screening and toxicology tests, than they have in therapeutic uses of stem cells and their derivatives.