Sentences with phrase «purebred dog populations»

Whereas human forms of CMS are often caused by compound heterozygosity, low levels of genetic diversity within purebred dog populations make simple recessive alleles more common.

Linebreeding practices expedite the appearance of recessive diseases in purebred dog populations.

The USA purebred dog population can be divided into four main genetic clusters, or sub-populations, based on microsatellite genotypes: Asian and African ancestry dogs, Mastiff - like breeds, and Herding and Hunting dog groups [10].

The present study identified specific breed groupings that contributed to disorders being more frequently observed in the purebred dog population.

The present study illustrated that certain subpopulations of the purebred dog population were more likely to display certain conditions while other subpopulations were not statistically different than mixed - breed dogs in terms of disease prevalence.

This study suggests that subpopulations of the purebred dog population are more likely to exhibit certain inherited conditions while other subpopulations do not differ statistically from mixed - breed dogs in terms of how common these diseases are.

These seven conditions showed higher risk only for certain subgroups of the purebred dog population.

Such a bias would inflate the prevalence of conditions in the study's purebred dog population.

It is known that many individual breeds show a higher than expected frequency of some disorders [7 — 10] suggesting that the higher prevalence of those disorders may be restricted to discrete subsets of the purebred dog population.

In comparing the purebred dog population to the mixed - breed dog population for ten inherited conditions found at a higher frequency in purebred dogs, the current data indicate that risk for certain inherited disorders can be apportioned to specific purebred populations.

For ten other inherited conditions, the purebred dog population had greater prevalence than that seen in mixed - breeds: aortic stenosis, atopy / allergic dermatitis, gastric dilatation volvulus (GDV), early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, hypothyroidism, intervertebral disk disease (IVDD), and portosystemic shunt.

Not exact matches

Disorders with equal prevalence in purebreds or mixed breeds seemed to be more ancient mutations that are widely spread through the dog population

In contrast, disorders that occurred equally among purebred and mixed - breed dogs appeared to represent ancient gene mutations that had become widely spread throughout the dog population.

Purebred dogs were more likely to remain in their homes, leaving shelter populations that are 75 - 80 percent mixed breeds.

A study by UC Davis showed that there was a prevalence of genetic disorders in both populations (rescue and bred): «Recently derived breeds or those from similar lineages appeared to be more susceptible to certain disorders that affect all closely related purebred dogs, whereas disorders with equal prevalence in the two populations suggested that those disorders represented more ancient mutations that are widely spread through the dog population.»

Registered and unregistered purebred dogs were 33 % and 18 % (total = 51 %) of the dog population, respectively; the remainder (49 %) of dogs was either mixed or unknown breeds.

Strader established National Mill Dog Rescue in 2007 after learning about a large - scale breeding operation, or «puppy mill,» in Missouri that was closing down and auctioning off its purebred population.

Many purebred dogs are known to be predisposed to the condition, with many affected individuals within the populations.

To sum up, we can explain over 80 % of the variation within populations of purebred dogs with just six genetic variants.

In the same way that inbreeding among human populations can increase the frequency of normally rare genes that cause diseases, the selective breeding that created the hundreds of modern dog breeds has put purebred dogs at risk for a large number of health problems, affecting both body and behavior.

It is seen in both purebred and mix - breed dogs, but some breeds, like the Aussie, have a much higher incidence than is seen in dogs as a whole, due to the restricted gene pool typical of any purebred population.

Purebred dogs are under assault from extreme animal rightists who would like to see all domestic animal populations managed to extinction.

Purebred dogs were more likely to remain in their homes, leaving shelter populations at 75 - 80 percent mixed breeds.

So with infertility infecting the show - bred dog population, how will the upscale family find a purebred puppy?

While some purpose - bred guide, service, or ranch dogs may be immune to infertility disease as a result of less exposure to the general population, the crashing fertility rate in quality purebreds can not be ignored.

The loss of genetic diversity in purebred dogs can be attributed to two major population bottleneck events: the first occurring during domestication; and the second arising from breed formation where the repeated use of popular sires, line breeding, breeding for specific phenotypic traits, and promotion of the breed barrier rule, contributed to overall loss in genetic variation [15 - 19].

If we disqualified all of the dogs with the slightest elbow issue, we would lose 31 % of the breeding population in every generation, compounding a genepool problem that is historically present in purebred dogs, and far more dangerous to the dogs than any heritable disease.

The proportion of mixed - breed and subclassifications of purebred dogs for each of those conditions was determined to distinguish what specific backgrounds may contribute to the inherited conditions seen with higher prevalence in the purebred population or if in fact, purebreds as a whole were more at risk than the mixed - breed dogs.

For each disorder, healthy controls seen at the hospital during that same time period were matched for age, weight, and sex to each affected dog to determine risk of disease presentation in the purebred group as compared to that of the mixed - breed population.

Odds ratios of inherited disorders between purebred dog categories and the mixed - breed dog population diagnosed over a 15 - year period

Previous studies indicate that some inherited disorders do not have significantly different prevalence across both the purebred and mixed - breed dog populations [6] which may represent ancient disease liability genes that preceded breed formation that are now distributed throughout the canine population as a whole or reflect recent purebred contributions to mixed - breed individuals.

We recently have reported that for 13 inherited disorders, there were no statistically detectable differences in risk of disease presentation between the purebred and mixed - breed dog populations and one condition was more prevalent in mixed - breeds [6].

For some disorders, such as hypothyroidism, purebred dogs may be more likely diagnosed with the condition due to pre-breeding health screens that are rarely done in the mixed - breed population.

Disorder counts, prevalence % (prev), and 95 % confidence interval (low and high) for inherited disorders between purebred dog categories and the mixed - breed dog population diagnosed over a 15 - year period

For aortic stenosis, GDV, early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, and portosystemic shunt, most purebred groups were not statistically distinct from the mixed - breed population with higher prevalence in purebreds restricted to distinct subsets of purebred dogs.