By getting back to basics, they reasoned, scientists might stand a chance of actually understanding
the purpose of every single gene in a living cell.
Not exact matches
It is surprising to find that a
single gene (ESRP), through its ancestral biological role (cell adherence and motility) has been used throughout the animal scale for very different
purposes: from the immune system
of an echinoderm to the lips, lungs or inner ears
of humans,» states professor Jordi Garcia - Fernàndez,
of the University
of Barcelona's Department
of Genetics, Microbiology and Statistics and the IBUB.
(This explains why rare
single -
gene diseases are more common in such groups; although studying such diseases is not the
purpose of the East London study, it is the focus
of another large U.K. study, the 100,000 Genomes Project.)
However, if the
purpose of such a scan is to identify candidate
genes, then — as with
single -
gene studies — more detailed follow - up and functional validation
of at least some
of the key
genes of interest are necessary to shore up the evidence.