Sentences with phrase «pylori colonized»
And H. pylori colonized Europe in two waves, one of them corresponding to the arrival of farmers from the Middle East.
http://www.sciencemag.org/ Not exact matches
For Helicobacter pylori, a pathogenic bacterium that colonizes over 40 percent of the world population and is associated with gastric cancer, the team discovered that epigenetic heterogeneity can quickly emerge as a single cell divides, and different subpopulations with distinct methylation patterns have distinct gene expressions patterns.
Chemotactic machinery guides H. pylori into the damage site to colonize, and then other virulence factors take over to make sure the site stays just as tasty in the long term by slowing repair of any damage.»
They found that H. pylori preferentially colonizes stomach tissue at injured ulcer sites, and there impairs healing of the damaged tissue.
The work began, according to Balloux, when the pair decided to combine their data sets on human populations and pathogens to see if they could determine «when Helicobacter pylori first infected humans and [if this could] shed light on when and how anatomically modern humans colonized the world.»
Helicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's population.
Based upon these data, we hypothesize that strain - selective activation of NF - kB and / or MAPK by H. pylori cag + strains regulates MMP - 7 expression, which may contribute to the augmentation in carcinogenic risk associated with these strains by attenuating apoptosis within chronically colonized mucosa.
Our experiments have recently shown that MMP - 7 is detected exclusively in human mucosa colonized by cag + strains, and these same H. pylori strains selectively induce MMP - 7 in vitro through cag - mediated activation of NF - kB and MAPK.
Gastric adenocarcinoma is the second leading cause of cancer - related death in the world, and Helicobacter pylori, a bacterial species that persistently colonizes the human stomach and induces chronic gastritis, is the strongest known risk factor for this malignancy.
«Being colonized by H. pylori is not necessarily detrimental to the host.