Sentences with word «pyrimidine»

TAR RNA forms a stable hairpin that includes a six - residue loop, a trinucleotide pyrimidine bulge, and extensive duplex structure.

Furthermore, the majority of mutations in cutaneous melanoma are C → T transitions at pyrimidine dimers, a pattern characteristic of UV - induced DNA damage; mucosal melanoma is not enriched in this mutational pattern.

The radiation and harsh temperatures broke down pyrimidine in the ice and formed new compounds related to life, such as uracil and cytosine.

Scientists at the NASA Ames Research Center went even further in 2015 when they exposed the organic molecule pyrimidine, found in meteorites, to interstellar conditions.

75 children were administered cranberry extract, while the other 117 were administered trimethoprim, a bacteriostatic antibiotic derived from trimethoxybenzyl pyrimidine, used almost exclusively to treat urinary infections.

Using an antibody test, the researchers found 40 % to 50 % fewer pyrimidine dimers in the treated skin samples.

This enzyme, called photolyase, finds and corrects pyrimidine dimers, an abnormal linkage between two neighboring DNA building blocks.

For example, a recent patent application provided a series of variously substituted pyrimidines claimed as CXCR4 antagonists.

According to enzyme classification, ENTPD8 is involved in purine and pyrimidine metabolism.

Frozen in ice under ultraviolet radiation, high vacuum and low temperature, the pyrimidine turned into uracil, cytosine and thymine, major components of earthly DNA and RNA.

Competition and interference experiments show that the Tat - derived fragments bind to double - stranded RNA and interact specifically at the pyrimidine bulge and adjacent duplex of TAR.

TAP comes from a family of compounds known as pyrimidines, as do the RNA bases C and U. CA, meanwhile, is a close pyrimidine relative.

In others, they changed pyrimidine RNA nucleotides, with cytidine or uracil bases, into pyrimidine DNA nucleotides with cytidine or thymidine bases.

So far, our structures span protein families such as cyclophilins, kinases and proteases as well as pathways for biosynthesis, salvage and metabolism of isoprenoids, fatty acids, phospholipids, pyrimidines, purines and polyamines.

† Ribose is the vital structural backbone of critical cellular compounds called purines and pyrimidines.

Our bodies must have an adequate supply of purines and pyrimidines to form major cellular constituents such as our genetic material (DNA and RNA), numerous cofactors, certain vitamins, and, importantly, adenosine triphosphate (ATP).

Pyriproxyfen is a pyrimidine derivative which prevents the larvae developing into adulthood and stops reproduction.

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