Sentences with phrase «pyruvate kinase»

Pyruvate kinase (PK) deficiency is an inherited lack of an enzyme (pyruvate kinase) in the red blood cells of an affected animal.

Pyruvate kinase (PK) deficiency has been found in the breed and glycogen storage disease type IV, an inherited abnormality of glucose metabolism, is also seen in Norwegian Forest cats.

Pyruvate kinase deficiency has been identified in the breed, as has progressive retinal atrophy (PRA) and flat chested kitten syndrome.

Progressive retinal atrophy (PRA) has been identified in the breed, as has Pyruvate kinase (PK) deficiency.

The enzyme pyruvate kinase can be found in the biochemical pathway responsible for providing the red blood cell with energy.

Such was the case with the lethal recessively inherited disease, pyruvate kinase hemolytic anemia (PKHA.)

Hemolytic anemia (destruction of RBCs) due to varied hereditary defects are seen more so in certain breeds, including English Springer Spaniels and less commonly Cocker Spaniels (phosphofructokinase [PFK] deficiency), and in Basenjis, Beagles, West Highland White Terriers, Cairn Terriers, Miniature Poodles, Toy Eskimos and Dachshunds (pyruvate kinase [PK] deficiency).

The Basenji, West Highland White terrier, English springer spaniel, Alaskan malamute, poodle and beagle breeds can be congenitally predisposed to this condition due to defects in enzymes (such as pyruvate kinase) or in the red blood cells.

Somalis, like Abyssinians, could develop a hereditary health issue called pyruvate kinase deficiency causing intermittent anemia.

Another disorder which can give x-ray pictures very similar to the «milky» or «cloudy» appearance of panosteitis is erythrocyte pyruvate kinase (PK) deficiency.

Pyruvate kinase (PK) deficiency in Basenji dogs is an inherited lack of an enzyme (pyruvate kinase) in the red blood cells of an affected animal.

Pyruvate kinase deficiency: a deficiency of a specific red blood cell enzyme.

Researchers also find the pyruvate kinase (PK) enzyme intriguing.

The side effect was first observed earlier this month at the American Society of Hematology conference, where CEODavid Schenkein spoke with CNBC about the safety of one of the molecules in its drug, which was meant to treat pyruvate kinase deficiency, a rare, genetic anemia.

Shares of Agios Pharmaceutical shed 12 percent Monday amid concern about the safety of one of the molecules in its drug to treat pyruvate kinase deficiency, a rare, genetic anemia.

Not exact matches

Among the other genes she says play a role in thoroughbred performance are peroxisome proliferator - activated receptor - γ coactivator - 1 alpha (PGC - 1α), which is involved in skeletal muscle adaptation to exercise; pyruvate dehydrogenase kinase, isozyme 4 (PDK4), involved in glucose regulation, expression of which increased almost fourfold after sprints; and cytochrome c oxidase subunit 4 isoform 2 (COX 4I2), involved in respiration.