Sentences with word «quadruplex»

The team designed the reaction system so that the product of CHA reaction has G - quadruplex structures, which is suitable to generate fluorescence.

He studies DNA and RNA quadruplexes, nucleic acid structures that were first visualized via confocal microscopy in fixed, dead cells.

Using multiphoton microscopy, he could confirm that quadruplexes exist in living cells, indicating they likely have some function there.

Both media had been in mainstream use for about a decade before someone figured out that the existing technology actually had far higher bandwidth than was initially realized (for the telegraph, the discovery of duplex and quadruplex transmission).

This top view of a G - quadruplex shows its structure in the DNA of a human telomere, where they frequently form.

It appears to do this by targeting little knots in their DNA, called quadruplexes, which are very different from normal DNA and which are especially found in faulty genes.

The research, which could re-ignite interest in the use of DNA - based wires and devices in the development of programmable circuits, appears in the journal Nature Nanotechnology under the title «Long - range charge transport in single G - quadruplex DNA molecules.»

The formation of CEB1 G - quadruplexes also stimulates gross chromosomal rearrangements.

This was further confirmed by using the PhenDCs G4 - quadruplexes ligands developed by the group of M - P.

Stanford University School of Medicine Pre-clinical validation of g - quadruplex drugs that target MYC to treat cancer

In this experimental system, we can recapitulate both ICL repair and G - quadruplex replication in a test tube, allowing us to gain insights in their molecular mechanisms.

Crucially, the antibody fragment didn't detect DNA in helical form, nor did it recognise «G - quadruplex structures» (a structurally similar four - stranded DNA arrangement).

The G - quadruplex is like a three - dimensional tower with multiple floors.

In place of rungs, the twisting, four - sided tower has platforms with a guanine nucleotide on each of four corners, hence the name G - quadruplex.

G - quadruplexes may be linked to cancer, speculates molecular biologist David Tannahill, a member of the Cambridge team.

A single strand of DNA can fold onto itself to form a G - quadruplex, or guanines from multiple strands can bond to form the four - stranded structure.

By using fluorescent molecules that bind to G - quadruplexes to generate strong fluorescence, the team could develop high performance RNase H detection method that overcomes the limitations of existing techniques.

In addition, the compound targeted a type of DNA architecture, called «G - quadruplex,» that is associated with cancer.

In vitro and in vivo analyses showed that CEB1 repeats formed stable G - quadruplex (G4) secondary structures and that the Pif1 protein unwinds these structures efficiently.

Our genome contains many G - rich sequences that can form stable secondary structures named G - quadruplex structures.

Her group studies how toxic DNA lesions, called DNA interstrand crosslinks (ICLs), are repaired and how secondary DNA structures (G - quadruplexes) are resolved.

Currently, we focus on understanding how toxic DNA lesions, called interstrand crosslinks (ICLs), are repaired, and how stable secondary DNA structures (G - quadruplexes) are resolved.

Our aim is to understand how G - quadruplexes are normally resolved to allow faithful DNA replication.

This stalling is transient and G - quadruplexes are readily resolved and faithfully replicated in our system.

Using a model system that combines Xenopus egg extracts and DNA templates containing specific G - quadruplex structures we have recently shown that replication stalls in close proximity of such a structure.

Multi-family homes that contain up to 4 units, such as duplexes, triplexes, and quadruplexes, could qualify for reverse mortgage loans as long as one of the units is the main residence.

He then builds on traditional Muslim tessilated designs to turn them into honeycombs with duplex, triplex, quadruplex or sextuplex units.

In Honeycomb housing, we sub-divide the building lots into 2, 3, 4 or 6, to create duplex, triplex, quadruplex or sextuplex units.»

There are duplexes and quadruplexes in all the areas you are already searching.

Because this is a quadruplex, I need further income stability to get my FHA loan approved because FHA doesn't like the fact that my W - 2 is through a family business.