PULLMAN, Wash. — Discovery of the first high -
quality genome of quinoa, published this week in Nature, could help create healthier, tastier varieties of this protein - packed «super food.»
A motivated high school student with access to a nearby biology lab can assemble a reference -
quality genome of an actual species, like a butterfly, for the cost of a science fair project.»
By comparing key sites on the tooth DNA with corresponding sites in the high -
quality genomes of the Denisova girl, Neandertals, and modern humans, they revealed that the Denisovan inhabitants in that one cave were not closely related.
Three research groups sequenced high -
quality genomes of 787 people from over 270 populations.
«Sequencing technology and computational biology,» Eichler and his team wrote in their paper, «have now advanced to the stage where individual laboratories can generate high
quality genomes of mammals.
A group of scientists from the United States, Sweden, Canada, and the UK, has sequenced and analyzed the complete high -
quality genomes of two woolly mammoths...
Not exact matches
With this in mind, the Materials
Genome Initiative is building databases
of material properties like strength, density and other things, and also includes computer models to predict what processes will achieve the
qualities a manufacturer is looking for.
DNA sequencing to create fine wine: The West Australian Department
of Agriculture and Food (DAFWA) and the University
of Western Australia (UWA) are leading a national project that uses grape
genome sequencing to examine how DNA make - up
of the vine affects the taste and
quality of wine...
Fourth, higher
quality maternal interactions have been shown to improve brain development at 5, 10 and 24 months.34 Fifth, there is growing evidence to suggest that the beneficial effects
of exclusive breastfeeding may be moderated by the infant's
genome, 35,36 and the metabolism
of the fatty acids in maternal breast milk.37 For example, Krol et al. 36 showed that infants exclusively breastfed for a longer duration (above the 50th percentile) showed a heightened sensitivity and interest in a happy visual stimulus (eyes) than infants exclusively breastfed for a shorter duration (below the 50th percentile).
When the scientists analyzed the
genomes of 80 birch trees from across Europe, they discovered a rich array
of selective sweeps in genes that influence important
qualities such as tree growth and wood production.
«The problem in older women is the
quality of the nuclear
genome in their eggs, and adding more mitochondria will not help that problem,» she says.
The estimate
of the number
of human genes has been repeatedly revised down from initial predictions
of 100,000 or more as
genome sequence
quality and gene finding methods have improved, and could continue to drop further.
The mouse, dog and human
genomes are
of high
quality whereas the three others are at different stages
of analysis completion.»
The performance
of our workflow was assessed on vertebrate
genome assemblies
of various
qualities (platypus, pig, horse, dog, mouse and human).
«For chloroplast
genome recovery from total DNA sequence data, the deliberate identification
of reads that represent chloroplast DNA inserts into the nuclear
genome allowed us to attain a higher -
quality chloroplast
genome assembly in a time - and cost - effective way,» Garaycochea explains.
In any case, however, high
quality nuclear
genome data from more than one individual would be necessary to fully investigate this proposed wave
of human migration out
of Africa, and is an intriguing area for future study.
The first high
quality draft
of the mouse
genome has been greeted by geneticists as a «Rosetta stone» that will help unravel the secrets
of our own genes.
«To our knowledge this is the longest
genome sequence with the highest
quality ever obtained for an extinct avian species,» Hung and his colleagues wrote
of the achievement.
In natural, unaltered organisms, she explains, each sequence
of DNA in a
genome codes for a particular outcome, expressed as a protein that determines a
quality of the individual or even the species as a whole.
The
genomes could help breeders produce trees with better wood
quality and insect resistance, says John MacKay
of Laval University in Quebec, who worked on both spruce
genomes.
«The
quality of this sequence is comparable to the first sequencing
of the human
genome as published 15 years ago, which revolutionized biomedical research at that time,» enthuses Matthias Platzer — research group leader at the FLI and involved in both the human and fish
genome sequencing progressions.
This image depicts a phylogenetic tree
of over 3,800 high
quality and non-redundant bacterial
genomes.
The system is designed for projects such as rapid and cost - effective generation
of high -
quality, whole -
genome de novo assemblies.
But until recently, fungaria were
of limited use for genetic research because
of the technical complexity
of genome sequencing and the poor
quality of DNA samples obtained from old, dried specimens.
While the technology was used with the goal
of attaining very high
quality genome assemblies, DOE JGI scientists have now additionally taken advantage
of this sequencing platform to explore epigenetic (5mC, 6mA) modifications.
That's easy: A team
of scientists from the United States and France has produced a high -
quality draft
genome of Coffea canephora.
In the past 6 months, these approaches have led to a flood
of high -
quality animal and plant
genomes in preprints and published papers.
However, that DNA was not
of high enough
quality to enable a complete
genome analysis.
Pääbo will continue sequencing Neanderthal DNA until he has a
genome that is similar in completion and
quality to the existing map
of the chimpanzee
genome.
To overcome the extreme genomic complexity, the team used new long - read sequencing technology that boosted the
quality of the
genome sequence obtained by more than one hundred fold over standard short - read approaches.
The discovery, the product
of a multiyear effort to provide a high -
quality full
genome map
of the oil palm plant and to scour the sequence for genes
of importance to both science and industry, has major implications for agriculture and the environment.
Yet no gene or
genome can ever tell us what sorts
of qualities those will be.
That genetic explanation was finally made possible because
of technology that enabled the lab to perform high -
quality sequencing
of specific
genome regions.
We generated a high -
quality draft
genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms.
But these
genomes were too low
quality to produce a reliable catalog
of differences.
About half
of the 31 copies came from the girl's mother and half from her father, producing a
genome «
of equivalent
quality to a recent human
genome,» says paleoanthropologist John Hawks
of the University
of Wisconsin, Madison, who was not part
of the team.
The
genome of the Western lowland gorilla has now been sequenced and assembled at a high level
of quality beginning to approach that
of the mouse and human
genome.
«For the first time in animals, we have assembled a high -
quality genome, permitting the discovery
of all the genetic differences between two individuals within a species,» said Mahul Chakraborty, a postdoctoral scholar in the Emerson laboratory and first author on the study.
He is a leader
of the recently assembled Simons
Genome Diversity Project, which contains 300 high -
quality genomes from 142 populations, including the San.
The Mouse
Genome Sequencing Consortium publishes its efforts of a high - quality sequence and analysis of the mouse g
Genome Sequencing Consortium publishes its efforts
of a high -
quality sequence and analysis
of the mouse
genomegenome.
To build MIDAS, researchers first generated a database
of 31,007 high -
quality bacterial
genomes.
In collaboration with a group
of international colleagues, BTI researchers created a high -
quality draft
genome sequence
of the whitefly and identified genes that code for proteins.
To carry out projects in
genome analysis that will lead to significant improvements in people's health and
quality of life, in collaboration with the Catalan, Spanish, European and International research and clinical community.
• Genetic
quality control monitoring Whole
genome scanning (rapid or more detailed) for routine strain background monitoring, or in case
of suspected contamination error, is a quick, inexpensive and reliable method compared to physical, immunological and biochemical assays, traditionally used for genetic
quality assessment.
This information would then be added into the core Ensembl gene - set (the reference zebrafish
genome used by researchers around the world) in such a way as to increase the quantity and
quality of the gene - set without adding artifacts or pseudogenes.
James Giovannoni generated the gene expression data through RNA - sequencing and Lukas Mueller provided additional analysis to confirm the
quality of the
genome assembly.
This effort is expected to generate a high -
quality resource for those responsible for the management
of wild salmon stocks and the salmon aquaculture industry, as well as providing a reference
genome for work with other salmonids.
An international team
of researchers has produced the first high -
quality genome sequence for the bottle gourd, also known as calabash, and reconstructed...
Moreover, we demonstrated that although the Oxford Nanopore technology is a relatively new sequencing technology, currently with a high error rate, it is already useful in the generation
of high -
quality genome assemblies.
A Sanger / pyrosequencing hybrid approach for the generation
of high -
quality draft assemblies
of marine microbial
genomes.