Sentences with phrase «quality genome sequence»

An international team of researchers has produced the first high - quality genome sequence for the bottle gourd, also known as calabash, and reconstructed...

Since its introduction a decade ago, whole - genome shotgun sequencing (WGS) has been the main approach for producing cost - effective and high - quality genome sequence data.

It was so small that the team were only able to obtain a low - quality genome sequence.

He presented a talk about the high - quality genome sequences from three important food crops in the gourd family at the Cucurbita workshop.

Not exact matches

DNA sequencing to create fine wine: The West Australian Department of Agriculture and Food (DAFWA) and the University of Western Australia (UWA) are leading a national project that uses grape genome sequencing to examine how DNA make - up of the vine affects the taste and quality of wine...

The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further.

To obtain the high - quality reference genome needed for this research, the team sequenced a domestic female Abyssinian cat named Cinnamon.

«For chloroplast genome recovery from total DNA sequence data, the deliberate identification of reads that represent chloroplast DNA inserts into the nuclear genome allowed us to attain a higher - quality chloroplast genome assembly in a time - and cost - effective way,» Garaycochea explains.

«To our knowledge this is the longest genome sequence with the highest quality ever obtained for an extinct avian species,» Hung and his colleagues wrote of the achievement.

Three research groups sequenced high - quality genomes of 787 people from over 270 populations.

In natural, unaltered organisms, she explains, each sequence of DNA in a genome codes for a particular outcome, expressed as a protein that determines a quality of the individual or even the species as a whole.

«The quality of this sequence is comparable to the first sequencing of the human genome as published 15 years ago, which revolutionized biomedical research at that time,» enthuses Matthias Platzer — research group leader at the FLI and involved in both the human and fish genome sequencing progressions.

But until recently, fungaria were of limited use for genetic research because of the technical complexity of genome sequencing and the poor quality of DNA samples obtained from old, dried specimens.

While the technology was used with the goal of attaining very high quality genome assemblies, DOE JGI scientists have now additionally taken advantage of this sequencing platform to explore epigenetic (5mC, 6mA) modifications.

Pääbo will continue sequencing Neanderthal DNA until he has a genome that is similar in completion and quality to the existing map of the chimpanzee genome.

To overcome the extreme genomic complexity, the team used new long - read sequencing technology that boosted the quality of the genome sequence obtained by more than one hundred fold over standard short - read approaches.

If genome sequencing is going to have true medical impact, it needs to get up to [a higher] diagnostic quality level.

The discovery, the product of a multiyear effort to provide a high - quality full genome map of the oil palm plant and to scour the sequence for genes of importance to both science and industry, has major implications for agriculture and the environment.

That genetic explanation was finally made possible because of technology that enabled the lab to perform high - quality sequencing of specific genome regions.

«Sequencing technology and computational biology,» Eichler and his team wrote in their paper, «have now advanced to the stage where individual laboratories can generate high quality genomes of mammals.

The genome of the Western lowland gorilla has now been sequenced and assembled at a high level of quality beginning to approach that of the mouse and human genome.

The Mouse Genome Sequencing Consortium publishes its efforts of a high - quality sequence and analysis of the mouse gGenome Sequencing Consortium publishes its efforts of a high - quality sequence and analysis of the mouse genomegenome.

In collaboration with a group of international colleagues, BTI researchers created a high - quality draft genome sequence of the whitefly and identified genes that code for proteins.

A group of scientists from the United States, Sweden, Canada, and the UK, has sequenced and analyzed the complete high - quality genomes of two woolly mammoths...

James Giovannoni generated the gene expression data through RNA - sequencing and Lukas Mueller provided additional analysis to confirm the quality of the genome assembly.

Moreover, we demonstrated that although the Oxford Nanopore technology is a relatively new sequencing technology, currently with a high error rate, it is already useful in the generation of high - quality genome assemblies.

High - Quality Draft Genome Sequence of Low - pH - Active Veillonella parvula Strain SHI - 1, Isolated from Human Saliva within an In Vitro Oral Biofilm Model.

The call will enable high quality Swedish research projects to access whole genome sequencing at a greatly reduced cost.

The work consisted of performing whole - genome sequencing on 1,011 samples of yeast which yielded 1,625,809 high - quality reference - based SNPs.

Here we report a high - quality draft genome sequence of the domestic dog (Canis familiaris), together with a dense map of single nucleotide polymorphisms (SNPs) across breeds.

Using next - generation sequencing, the complete genome sequence of ancient individuals can now be deciphered (15), with qualities rivaling the qualities of modern genomes (16 ⇓ — 18).

In collaboration with the genome sequencing centres, Vega attempts to present consistent high - quality annotation of the published human chromosome sequences.

The quality and scale of deCODE's in - house, CLIA - registered genotyping laboratory underpins deCODE's global leadership in the discovery of variations in the sequence of the human genome conferring risk of common diseases.

The new high - quality PcyM assembly has an improved representation of the subtelomeric regions of the genome, which now encompass nearly 40 % of the genome sequence.

A ROC curve is generated for each sequenced genome to demonstrate the tradeoff in sensitivity and specificity as a function of two metrics that are well correlated with quality of the event detection: insertionScore and insertionDnbCount.

Genome sequencing of the TRAC clinical samples has now been completed, generating terabytes of data that were processed by the sequence - analysis pipeline team led by Jim Stalker, to produce quality - controlled information about many thousands of variants for each sample.

As part of their technology development goals, the scientists will also work to further improve sequence quality — decoding exomes and genomes as accurately and as cheaply as possible.

«The high - quality pumpkin genome sequences will lead to more efficient dissection of the genetics underlying important agronomic traits, thus accelerating the breeding process for pumpkin improvement,» said Fei.

The sequencing work for this project has been done at the Wellcome Trust Sanger Institute, and the next phase of work is to develop a detailed catalogue of variants and a reference panel of quality - controlled genotyping data that can be used for accurate imputation in genome - wide association studies of malaria and other diseases.

With these additional specimens, we hoped to find the individual with the best quality DNA for the first full genome sequence.

Motivation: Single Molecule Real - Time (SMRT) sequencing technology and Oxford Nanopore technologies (ONT) produce reads over 10kbp in length, which have enabled high - quality genome assembly at an affordable cost.

Following the development of a computational pipeline, including a new de novo assembler for RNA virus genomes, to generate larger contiguous sequences (contigs) from the abundance of short sequence reads that characterise the data, another area that determines genome sequencing success is the quality and quantity of the input RNA.

We first assessed the sequencing quality of each platform with respect to distributing reads most evenly across the genome.

Scientists have sequenced the genome of a green alga that has drawn commercial interest as a strong producer of quality lipids for biofuel production.

High - quality de novo genome assembly of the Dekkera bruxellensis UMY321 yeast isolate using Nanopore MinION sequencing

She emphasized several times the value of TCGA's GBM sequencing as a reference cancer genome, with high - quality mutations already profiled for mutations, gene expression, etc..

The HudsonAlpha Clinical Services Lab provides high quality, state of the art whole genome sequencing with a turnaround time of 90 days for interpreted results.

It must also be clearly stated that sufficient genetic material is available from the study subjects such that a range of sequencing technologies can be used in order to produce high quality genome assemblies.

The HudsonAlpha Clinical Services Lab provides high quality, state of the art whole genome sequencing with a turnaround time of 90 days for fully - interpreted results.

In fact, Ostrander, who works at the NHGRI's Cancer Genetics and Comparative Genomics Branch, was one of the lead authors of a white paper arguing for support to sequence the dog genome at a level of quality already available at the time for the mouse, «to better understand the genetic basis of complex diseases affecting both human and dog.»