Sentences with phrase «quantitative trait locus»

The genomics era has had a profound impact on life science research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated with specific diseases.

They then used a genetic technique called quantitative trait locus analysis to search for the genes involved in generating phenolics in the most promising progeny.

Confirmation of quantitative trait loci influencing methamphetamine - and opioid - induced locomotor stimulation using B6.D2 congenic strains Camron Bryant, Dept of Human Genetics, University of Chicago, USA

They then used a genetic technique called quantitative trait locus analysis to search for the genes involved in generating phenolics in the most promising progeny.

Bentolila, S., Babina, A. M., Germain, A., and Hanson, M. R. (2013) Quantitative trait locus mapping identifies REME2, a PPR - DYW protein required for editing of specific C targets in Arabidopsis mitochondria.

LG / J mice are often compared to SM / J (Stock No. 000687) for quantitative trait locus analysis in the areas of atherosclerosis, obesity, and mandible size.

• Describe how protein quantitative trait loci (pQTLs) can provide insights into disease biology and improve the efficiency of drug development

In the lab, we created a hybrid cross between two genera that differ in microhabitat in the wild and behavior in the lab, and used a ddRAD - seq linkage - mapping strategy to identify quantitative trait loci (QTL) associated with species - specific behaviors.

Simulating the yield impacts of organ - level quantitative trait loci associated with drought response in maize: A «gene - to - phenotype» modeling approach.

As a post doctoral fellow he shifted his interest to the use of genetic mouse modules to map quantitative trait loci involved in various hematopietic stem cell traits.

Saturday, Oct. 21, 11:20 - 11:40 a.m., South Hall B, South Building Featured Plenary Abstract: Massively parallel reporter assays combined with cell - type specific expression quantitative trait loci profiling identified a functional melanoma risk variant in HIV - 1 inhibitor gene, MX2 J. Choi, National Cancer Institute, et al

Our first striking observation was that over one half of measured genes are affected by common genetic variation in human populations — called expression quantitative trait loci or eQTLs.

SM / J mice carry a number of rare polymorphic alleles and are often matched to other strains for quantitative trait locus analysis.

These regions can be clumped into larger areas of the genome called quantitative trait loci, which are known to contain genes that produce a specific physical effect, such as shaggy hair.

High - resolution linkage and quantitative trait locus mapping aided by genome survey sequencing: building up an integrative genomic framework for a bivalve mollusc.

We identified 1209 protein quantitative trait loci (pQTL) with overwhelming majority of local pQTL and only 5.8 % of distal pQTL.

SM / J mice carry a number of rare polymorphic alleles and are often matched to LG / J (Stock No. 000675), A / J (Stock No. 000646) or NZB / BINJ (Stock No. 000684) for quantitative trait locus analysis.

IRRI scientists have identified several key regions of the rice genome — called quantitative trait loci (QTLs)-- that give the rice drought tolerance and improve rice grain yield under such conditions.

Led by a team of world - renowned geneticists, our solutions are applicable for questions focused on single - nucleotide polymorphism discovery and diagnostics, marker - assisted selection, quantitative trait locus mapping, genome - wide association studies, phylogenomics, and more.

Engelhardt's group was responsible for mapping associations between genetic variants and gene expression levels on different chromosomes, a connection known as «trans - expression quantitative trait loci (trans - eQTLS).»

The exciting aspect of submergence was that they could bring in what is known as a «quantitative trait locus» — a more genetically complex region that influences measurable changes to the crop.

In the past three years, dozens of genetic variants and Quantitative Trait Loci (QTL) have been identified which influence breed - defining traits including those for skeletal size [2], coat color [3], [4], leg length [5], hairlessness [6], wrinkled skin [7], hair length, curl, and texture [8], and presence of a dorsal fur ridge [9].

These types of studies yielded thousands of expression quantitative trait loci (eQTLs), along with insights into how genetic variation influences transcription.

Further, his group pioneered expression quantitative trait locus (eQTL) studies, which enabled variation in global gene expression to be applied to genetics of complex human diseases.

We have approaches in hand to search for expression quantitative trait loci (eQTLs) and splicing quantitative trait loci (sQTLs).

We have pioneered studies demonstrating that low - yielding wild and exotic Oryza species harbor genes and quantitative trait loci (QTL) that can be used to enhance the performance of modern, high - yielding rice cultivars.

To achieve this Broad is leveraging FireCloud, our cloud platform for hosting data from The Cancer Genome Atlas (TCGA) that was funded through the National Cancer Institute's Cloud Pilots program, and extending it to manage data and run pipelines for RNA sequencing and expression Quantitative Trait Loci (eQTL) analyses, that were developed as part of the Genotype Tissue Expression (GTEx) project.

Linkage and quantitative trait loci (QTL) mapping were performed by combining our new genotypic data with a previously generated genetic map for this population, then adding rust disease data from our experiment to identify genomic regions associated with leaf rust resistance.

Quantitative trait loci for water - use efficiency in barley (Hordeum vulgare L.) measured by carbon isotope discrimination under rain - fed conditions on the Canadian Prairies, Theoretical and Applied Genetics 125: 71 — 90.

Four quantitative trait loci (QTL) have been identified through linkage mapping for cranial cruciate ligament disease in the Newfoundland breed (Wilke et al., 2009).

Based on our (Todhunter et al., 2005; Zhu et al., 2008; Mateescu et al., 2008; Phavaphutanon et al., 2009; Zhou et al., 2010) and others (Chase et al., 2005; Marschall and Distl, 2007, 2012) research, between 10 and 20 quantitative trait loci (QTL) likely control hip dysplasia expression.

Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP - 25, and 5HT1B