Sentences with phrase «radial glial»

The remarkable size expansion of the human neocortex is thought to partly arise from a second pool of neural stem cells, called the basal Radial Glial (bRG) cells (Fig. 1).

There are several different types of glial cells: astrocytes, oligodendrocytes, microglia, ependymal cells, radial glial, satellite cells, and schwann cells.

In rodents and humans, the developing cortex contains a layer of neural stem cells called radial glial cells that resides near the fluid - filled ventricles and produces cells that are precursors to neurons.

The stem cell closely resembles the radial glial cell in structure and behavior and, like the radial glia, has radial fibers which newborn neurons migrate along up to the neocortex.

Indeed, in the mutant ferrets, researchers traced the cerebral cortex deficits to a type of stem cell called outer radial glial cells (ORGs).

However, at the end of neurogenesis, radial glial loses its neurogenic ability and transforms into astrocytes, which continually divide to produce parenchymal astrocytes.

The cover image was created using images of neural rosettes derived from human iPSCs with and without a 15q11.2 microdeletion (round circles) and images of radial glial cells in the developing mouse cortex (thin filaments), and it is inspired by July 4th fireworks.

Neural stem cells called outer radial glial (oRG) cells help fuel the expansion of the unusually big human brain.