In rodents and humans, the developing cortex contains a layer of neural stem cells called
radial glial cells that resides near the fluid - filled ventricles and produces cells that are precursors to neurons.
Indeed, in the mutant ferrets, researchers traced the cerebral cortex deficits to a type of stem cell called outer
radial glial cells (ORGs).
The cover image was created using images of neural rosettes derived from human iPSCs with and without a 15q11.2 microdeletion (round circles) and images of
radial glial cells in the developing mouse cortex (thin filaments), and it is inspired by July 4th fireworks.
The stem cell closely resembles
the radial glial cell in structure and behavior and, like the radial glia, has radial fibers which newborn neurons migrate along up to the neocortex.
Not exact matches
Neural stem
cells called outer
radial glial (oRG)
cells help fuel the expansion of the unusually big human brain.
There are several different types of
glial cells: astrocytes, oligodendrocytes, microglia, ependymal
cells,
radial glial, satellite
cells, and schwann
cells.
The remarkable size expansion of the human neocortex is thought to partly arise from a second pool of neural stem
cells, called the basal
Radial Glial (bRG)
cells (Fig. 1).