Sentences with phrase «radiation and chemotherapy in»

«Based on this research, we are now conducting a first - in - human study combining the PARP inhibitor with radiation and chemotherapy in patients with locally advanced pancreatic cancer, with an ultimate goal of improving survival rates and treatment outcomes,» said Tuli.
«This is the first prospective and longitudinal study to characterize structural brain changes resulting from standard radiation and chemotherapy in patients with malignant brain tumors.

Not exact matches

As he completed his surgery, which resulted in the removal of 22 lymph nodes, and began chemotherapy and radiation in June, the relentless sickness began.
In contrast, the typical, less efficient method of treating cancer uses combinations of surgery, chemotherapy and radiation to kill cancer cells.
The Duke team collaborated with Memorial Sloan Kettering in New York to devise a chemotherapy and radiation protocol that could be administered at MSK so their son could be close to home.
-- who, before I ended up in the so - called last step, were with me daily as I was being bludgeoned with chemotherapy and radiation and moving around in a daze.
In the case of my illness, the prescribed first round of radiation and chemotherapy did its job of making the eventual surgery effective.
In a beautifully ironic twist for a natural chemical falsely accused of causing stomach cancer, capsaicin has been shown to be «absolutely effective» in alleviating the pain from oral stomatitis, mouth sores caused by cancer chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management CenteIn a beautifully ironic twist for a natural chemical falsely accused of causing stomach cancer, capsaicin has been shown to be «absolutely effective» in alleviating the pain from oral stomatitis, mouth sores caused by cancer chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management Centein alleviating the pain from oral stomatitis, mouth sores caused by cancer chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management Center.
In what often must seem like a wicked twist of fate, most patients who receive radiation or chemotherapy to the head and neck develop serious oral lesions.
I had 6 rounds of chemotherapy and 15 treatments of targeted radiation for a non Hodgkin's lymphoma tumor in right breast in 2014.
Stomatorrhagia (bleeding in the mouth) is commonly seen in patients undergoing chemotherapy and / or radiation therapy.
This non-sequitur is analogous to suggesting that those who document the age related rise in cancer mortality advocate routine chemotherapy and radiation for the middle aged.»
In particular, our pediatric radiation oncologists at Floating Hospital for Children offer special expertise in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherapIn particular, our pediatric radiation oncologists at Floating Hospital for Children offer special expertise in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherapin the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherapy.
Arizona Sen. John McCain, the 2008 Republican presidential nominee who was diagnosed with brain cancer in July, has completed his first round of radiation and chemotherapy, his daughter Meghan said.
Under a contract submitted to the county legislature, Sloan Kettering will spend $ 140 million in private funds to build a two - story, 105,000 - square - foot medical center to provide chemotherapy, radiation and other cancer treatments.
They told her she needed aggressive chemotherapy and radiation to kill the cancer cells in her softball - sized tumor.
All patients receive radiation and chemotherapy, yet despite the aggressive approach, the regimen fails in about one - third of patients with cervical cancer that has spread beyond the cervix but not outside the pelvis.
«In an earlier phase I clinical study, our group has shown that increasing the dose of radiation delivered daily with high precision and using image guidance may offset the need for chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in halIn an earlier phase I clinical study, our group has shown that increasing the dose of radiation delivered daily with high precision and using image guidance may offset the need for chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in halin improving survival, and it may also improve quality of life measures by reducing treatment periods in halin half.
In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recuIn patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recuin the bloodstream and allow the malignancy to recur.
As reported at the American Society of Clinical Oncology meeting in June, the vaccine, together with radiation and chemotherapy, prevented the brain tumor from reemerging after surgery for 12 months as compared with the typical six to seven months with no vaccine.
The initial experiments made use of cancer cells that Quiñones - Hinojosa and his team removed from willing patients and grew in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.
Autophagy has emerged as a key pathway that cancer cells use to survive in the face of assault by chemotherapy and radiation; however, autophagy as a potential druggable mechanism in patients who become resistant to BRAF inhibitors has not been investigated.
In our trial, however, the addition of radiation therapy directed at each of the cancerous areas greatly improved how patients responded to subsequent rounds of chemotherapy,» said Puneeth Iyengar, MD, PhD, lead author of the study and an assistant professor of radiation oncology at the University of Texas Southwestern Medical Center in DallaIn our trial, however, the addition of radiation therapy directed at each of the cancerous areas greatly improved how patients responded to subsequent rounds of chemotherapy,» said Puneeth Iyengar, MD, PhD, lead author of the study and an assistant professor of radiation oncology at the University of Texas Southwestern Medical Center in Dallain Dallas.
Patients with uveal melanoma receive surgery to remove the tumor — and in some advanced cases, the entire eye — as well as radiation therapy or chemotherapy.
In addition, TGen laboratory research also found that PPF increases the effectiveness of a standard - of - care chemotherapy drug called temozolomide (TMZ), and radiation, to treat glioblastoma.
Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist.
Scientists have moved a step closer to being able to preserve fertility in young boys who undergo chemotherapy and radiation treatments for cancer.
Lengner's group and others had previously shown that these reserve stem cells normally reside in a dormant state and are protected from chemotherapy and radiation.
In animal studies and early clinical trials, the drug known as Epo (for erythropoietin) appeared to counteract anemia caused by radiation and chemotherapy.
Results from recent clinical trials and studies in animals suggest that a class of anti-cancer drugs called angiogenesis inhibitors may be able to temporarily reduce interstitial pressure and improve the efficacy of chemotherapy and radiation treatments.
A highly targeted cancer radiation therapy may offer a safe and effective treatment option for elderly pancreatic cancer patients unable to undergo surgery or combined chemotherapy and radiation therapy, according to researchers at Henry Ford Hospital in Detroit.
When the researchers removed FAK from blood vessels that grew in melanoma or lung cancer models, both chemotherapy and radiation therapies were far more effective in killing the tumors.
«This paper reveals a metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilize existing redox active compounds, like vitamin C, to sensitize cancer cells to radiation and chemotherapy,» says co-author Garry Buettner, who was one of the first to propose that cancer cells might have a vulnerability to redox active compounds over 40 years ago.
The 11 evaluable patients enrolled in the brain cancer safety trial received three infusions of vitamin C a week for 2 months followed by two infusions per week for 7 months while receiving standard care radiation and chemotherapy.
They are hopeful that brain cancer responses to radiation and chemotherapy can be enhanced in these phase II trials.
Cognitive impairment can occur in cancer patients who are treated with a variety of therapies, including radiation therapy, hormone therapy, and chemotherapy.
Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS - variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.
Another derivative, called Allopurinol, is applied to prevent kidney blockage in gout patients and in cancer patients receiving radiation or chemotherapy.
This complexity contributes to its aggressive nature and resistance to conventional therapies such as chemotherapy and radiation therapy,» says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader of the Cancer Molecular Genetics research program at Massey Cancer Center, professor and chair of the Department of Human and Molecular Genetics at the VCU School of Medicine, and director of the VIMM.
«These tumors occur in up to 23,000 Americans annually, and are typically treated with surgical resection of the tumor followed by chemotherapy and radiation treatment.»
«Pancreatic cancer is a disease with a poor prognosis, mainly because of the inability to detect the tumor at an early stage, its high potential for early dissemination, and its relatively poor sensitivity to chemotherapy or radiation therapy,» according to background information in the article.
Damage of the kind duplicated in the laboratory occurs naturally after exposure to radiation and perhaps also after ingestion of toxic chemicals such as those used in chemotherapy.
Of the 4,868 women in this study, natural menopause was reported by 79 % of the women, 10 % as a surgical menopause and 11 % of women reported menopause due to other causes, such as radiation or chemotherapy.
In these therapies, the patient's own blood - producing bone marrow cells are treated with radiation and chemotherapy, and the blood of a twin or closely matched donor is instilled.
Their findings, to be published in the July issue of the journal Cancer Cell, could explain why some tumors don't respond to radiation or chemotherapy, and provide novel routes for the development of new anti-cancer therapies.
Surgery, radiation and chemotherapy do prolong survival by several months, but targeted therapies, which have been effective with other forms of cancer, have not lengthened survival in patients fighting glioblastoma.
This phase II trial studies how well chemotherapy and radiation therapy work in treating younger patients with newly diagnosed central nervous system germ cell tumors.
These include sophisticated techniques in diagnosis, surgical options, chemotherapy, hormonal therapy, biological therapy, and radiation therapy.
Standard treatment for children with medulloblastoma consists of surgery in combination with radiation and chemotherapy.
It is not yet known whether radiation therapy works better when given with or without combination chemotherapy and / or pazopanib hydrochloride in treating patients with non-rhabdomyosarcoma soft tissue sarcomas.
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