«Based on this research, we are now conducting a first - in - human study combining the PARP inhibitor with
radiation and chemotherapy in patients with locally advanced pancreatic cancer, with an ultimate goal of improving survival rates and treatment outcomes,» said Tuli.
«This is the first prospective and longitudinal study to characterize structural brain changes resulting from standard
radiation and chemotherapy in patients with malignant brain tumors.
Not exact matches
As he completed his surgery, which resulted
in the removal of 22 lymph nodes,
and began
chemotherapy and radiation in June, the relentless sickness began.
In contrast, the typical, less efficient method of treating cancer uses combinations of surgery,
chemotherapy and radiation to kill cancer cells.
The Duke team collaborated with Memorial Sloan Kettering
in New York to devise a
chemotherapy and radiation protocol that could be administered at MSK so their son could be close to home.
-- who, before I ended up
in the so - called last step, were with me daily as I was being bludgeoned with
chemotherapy and radiation and moving around
in a daze.
In the case of my illness, the prescribed first round of
radiation and chemotherapy did its job of making the eventual surgery effective.
In a beautifully ironic twist for a natural chemical falsely accused of causing stomach cancer, capsaicin has been shown to be «absolutely effective» in alleviating the pain from oral stomatitis, mouth sores caused by cancer chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management Cente
In a beautifully ironic twist for a natural chemical falsely accused of causing stomach cancer, capsaicin has been shown to be «absolutely effective»
in alleviating the pain from oral stomatitis, mouth sores caused by cancer chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management Cente
in alleviating the pain from oral stomatitis, mouth sores caused by cancer
chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management Center.
In what often must seem like a wicked twist of fate, most patients who receive
radiation or
chemotherapy to the head
and neck develop serious oral lesions.
I had 6 rounds of
chemotherapy and 15 treatments of targeted
radiation for a non Hodgkin's lymphoma tumor
in right breast
in 2014.
Stomatorrhagia (bleeding
in the mouth) is commonly seen
in patients undergoing
chemotherapy and / or
radiation therapy.
This non-sequitur is analogous to suggesting that those who document the age related rise
in cancer mortality advocate routine
chemotherapy and radiation for the middle aged.»
In particular, our pediatric radiation oncologists at Floating Hospital for Children offer special expertise in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherap
In particular, our pediatric
radiation oncologists at Floating Hospital for Children offer special expertise
in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherap
in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy
and multi-agent
chemotherapy.
Arizona Sen. John McCain, the 2008 Republican presidential nominee who was diagnosed with brain cancer
in July, has completed his first round of
radiation and chemotherapy, his daughter Meghan said.
Under a contract submitted to the county legislature, Sloan Kettering will spend $ 140 million
in private funds to build a two - story, 105,000 - square - foot medical center to provide
chemotherapy,
radiation and other cancer treatments.
They told her she needed aggressive
chemotherapy and radiation to kill the cancer cells
in her softball - sized tumor.
All patients receive
radiation and chemotherapy, yet despite the aggressive approach, the regimen fails
in about one - third of patients with cervical cancer that has spread beyond the cervix but not outside the pelvis.
«
In an earlier phase I clinical study, our group has shown that increasing the dose of radiation delivered daily with high precision and using image guidance may offset the need for chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in hal
In an earlier phase I clinical study, our group has shown that increasing the dose of
radiation delivered daily with high precision
and using image guidance may offset the need for
chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in hal
in improving survival,
and it may also improve quality of life measures by reducing treatment periods
in hal
in half.
In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recu
In patients who have undergone
chemotherapy and radiation, a small number of cancer cells can remain
in the bloodstream and allow the malignancy to recu
in the bloodstream
and allow the malignancy to recur.
As reported at the American Society of Clinical Oncology meeting
in June, the vaccine, together with
radiation and chemotherapy, prevented the brain tumor from reemerging after surgery for 12 months as compared with the typical six to seven months with no vaccine.
The initial experiments made use of cancer cells that Quiñones - Hinojosa
and his team removed from willing patients
and grew
in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to
chemotherapy and radiation,
and capable of creating new tumors.
Autophagy has emerged as a key pathway that cancer cells use to survive
in the face of assault by
chemotherapy and radiation; however, autophagy as a potential druggable mechanism
in patients who become resistant to BRAF inhibitors has not been investigated.
In our trial, however, the addition of radiation therapy directed at each of the cancerous areas greatly improved how patients responded to subsequent rounds of chemotherapy,» said Puneeth Iyengar, MD, PhD, lead author of the study and an assistant professor of radiation oncology at the University of Texas Southwestern Medical Center in Dalla
In our trial, however, the addition of
radiation therapy directed at each of the cancerous areas greatly improved how patients responded to subsequent rounds of
chemotherapy,» said Puneeth Iyengar, MD, PhD, lead author of the study
and an assistant professor of
radiation oncology at the University of Texas Southwestern Medical Center
in Dalla
in Dallas.
Patients with uveal melanoma receive surgery to remove the tumor —
and in some advanced cases, the entire eye — as well as
radiation therapy or
chemotherapy.
In addition, TGen laboratory research also found that PPF increases the effectiveness of a standard - of - care
chemotherapy drug called temozolomide (TMZ),
and radiation, to treat glioblastoma.
Despite improvements
in the past few decades with surgery,
chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist.
Scientists have moved a step closer to being able to preserve fertility
in young boys who undergo
chemotherapy and radiation treatments for cancer.
Lengner's group
and others had previously shown that these reserve stem cells normally reside
in a dormant state
and are protected from
chemotherapy and radiation.
In animal studies
and early clinical trials, the drug known as Epo (for erythropoietin) appeared to counteract anemia caused by
radiation and chemotherapy.
Results from recent clinical trials
and studies
in animals suggest that a class of anti-cancer drugs called angiogenesis inhibitors may be able to temporarily reduce interstitial pressure
and improve the efficacy of
chemotherapy and radiation treatments.
A highly targeted cancer
radiation therapy may offer a safe
and effective treatment option for elderly pancreatic cancer patients unable to undergo surgery or combined
chemotherapy and radiation therapy, according to researchers at Henry Ford Hospital
in Detroit.
When the researchers removed FAK from blood vessels that grew
in melanoma or lung cancer models, both
chemotherapy and radiation therapies were far more effective
in killing the tumors.
«This paper reveals a metabolic frailty
in cancer cells that is based on their own production of oxidizing agents that allows us to utilize existing redox active compounds, like vitamin C, to sensitize cancer cells to
radiation and chemotherapy,» says co-author Garry Buettner, who was one of the first to propose that cancer cells might have a vulnerability to redox active compounds over 40 years ago.
The 11 evaluable patients enrolled
in the brain cancer safety trial received three infusions of vitamin C a week for 2 months followed by two infusions per week for 7 months while receiving standard care
radiation and chemotherapy.
They are hopeful that brain cancer responses to
radiation and chemotherapy can be enhanced
in these phase II trials.
Cognitive impairment can occur
in cancer patients who are treated with a variety of therapies, including
radiation therapy, hormone therapy,
and chemotherapy.
Researchers have found that people with advanced head
and neck squamous cell carcinoma
and the KRAS - variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab
in combination with standard
chemotherapy and radiation.
Another derivative, called Allopurinol, is applied to prevent kidney blockage
in gout patients
and in cancer patients receiving
radiation or
chemotherapy.
This complexity contributes to its aggressive nature
and resistance to conventional therapies such as
chemotherapy and radiation therapy,» says Fisher, Thelma Newmeyer Corman Endowed Chair
in Cancer Research
and co-leader of the Cancer Molecular Genetics research program at Massey Cancer Center, professor
and chair of the Department of Human
and Molecular Genetics at the VCU School of Medicine,
and director of the VIMM.
«These tumors occur
in up to 23,000 Americans annually,
and are typically treated with surgical resection of the tumor followed by
chemotherapy and radiation treatment.»
«Pancreatic cancer is a disease with a poor prognosis, mainly because of the inability to detect the tumor at an early stage, its high potential for early dissemination,
and its relatively poor sensitivity to
chemotherapy or
radiation therapy,» according to background information
in the article.
Damage of the kind duplicated
in the laboratory occurs naturally after exposure to
radiation and perhaps also after ingestion of toxic chemicals such as those used
in chemotherapy.
Of the 4,868 women
in this study, natural menopause was reported by 79 % of the women, 10 % as a surgical menopause
and 11 % of women reported menopause due to other causes, such as
radiation or
chemotherapy.
In these therapies, the patient's own blood - producing bone marrow cells are treated with
radiation and chemotherapy,
and the blood of a twin or closely matched donor is instilled.
Their findings, to be published
in the July issue of the journal Cancer Cell, could explain why some tumors don't respond to
radiation or
chemotherapy,
and provide novel routes for the development of new anti-cancer therapies.
Surgery,
radiation and chemotherapy do prolong survival by several months, but targeted therapies, which have been effective with other forms of cancer, have not lengthened survival
in patients fighting glioblastoma.
This phase II trial studies how well
chemotherapy and radiation therapy work
in treating younger patients with newly diagnosed central nervous system germ cell tumors.
These include sophisticated techniques
in diagnosis, surgical options,
chemotherapy, hormonal therapy, biological therapy,
and radiation therapy.
Standard treatment for children with medulloblastoma consists of surgery
in combination with
radiation and chemotherapy.
It is not yet known whether
radiation therapy works better when given with or without combination
chemotherapy and / or pazopanib hydrochloride
in treating patients with non-rhabdomyosarcoma soft tissue sarcomas.