Guinan, a bone marrow transplant specialist, began by asking
her radiation therapy patients to provide her with fingernail and toenail clippings.
Not exact matches
For instance, most common adult solid tumors that are not cured by surgical removal are resistant to chemotherapy or
radiation control, yet drug
therapy is frequently offered as a «possibly effective» treatment because both
patient and physician want to believe it so.
Stomatorrhagia (bleeding in the mouth) is commonly seen in
patients undergoing chemotherapy and / or
radiation therapy.
There was also no change based on whether
patients had undergone hormone
therapy, a common treatment for prostate cancer which lowers the male hormone and can be combined with daily
radiation.
Currently, most breast cancer
patients are treated not only with surgery, but also
radiation, hormone
therapy or chemotherapy.
Unlike conventional chemotherapies and
radiation that indiscriminately eradicate fast - growing tissues and ravage people's bodies with side effects, new
therapies specifically target tumors using tailored cells from individual
patients.
The Moores Cancer Center's Molecular Tumor Board brought together medical, surgical and
radiation therapy oncologists, biostatisticians, radiologists, pathologists, clinical geneticists, basic and translational science researchers, and bioinformatics and pathway analysis specialists to discuss the intricacies of tumor genetics and tailor a personalized treatment plan for
patients with advanced cancer or who have exhausted standard
therapies.
Urbanic said the overall findings of the study suggest that there are some
patients with recurrent lung cancers who can be treated with another definitive course of
radiation therapy and still have a chance at a cure.
Despite complications sometimes more severe than with standard
radiation therapy — and costs that are much higher for taxpayers,
patients and insurers — proton beam
therapy is heavily marketed for treatment of prostate cancer.
Inside the University of Pennsylvania's Roberts Proton
Therapy Center,
radiation oncologists sit in front of colorful, detailed images of
patients» bodies, clicking mice and tapping keyboards.
This study analyzed preserved tumor samples from 43 prostate cancer
patients who later received
radiation therapy after rising PSA levels were detected following a radical prostatectomy.
A new study has identified a group of molecules in prostate - cancer cells that doctors might one day use to distinguish which
patients should be treated with
radiation therapy if rising PSA levels indicate their cancer has recurred after surgical removal of the prostate.
«Cervical cancer
patients are currently treated as a uniform group based on chemotherapy and
radiation regimens that help the largest percentage of people; however, one third of these
patients are not helped by standard
therapies,» Banister said.
In particular, the study suggests that two miRNAs — miR - 4516 and miR - 601 — in tumor cells along with Gleason score and lymph node status may help identify
patients who might experience rising PSA after they've been treated with
radiation therapy.
«These findings are important because it is currently hard to distinguish early which
patients will benefit from
radiation therapy following radical prostatectomy and which will receive no benefit,» says Bell.
«There's this commonly held belief that the longer you delay
radiation therapy, the more opportunity a
patient has for recovery from prostatectomy, and therefore the better long - term function in terms of urinary and bowel function — the longer you delay it, the better they'll function,» he said.
But up to 30 to 40 percent of these
patients experience rising PSA levels after surgery, and these
patients are often treated using
radiation therapy.
Led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), the retrospective study suggested that a pattern of molecules called microRNA (miRNA) in tumor cells might predict
patients» response to
radiation therapy.
Researchers compared two common postsurgical
therapies for metastatic brain tumors and found that stereotactic radiosurgery can provide better outcomes for
patients compared to whole - brain
radiation.
«The use of advanced technologies may allow
radiation therapy to be delivered in larger doses per treatment safely and potentially translate into an overall survival difference in NSCLC
patient populations while improving
patient quality of life through an acceleration of treatment courses,» said Dr. Iyengar.
Treatments include surgery to remove the prostate,
radiation therapy and active surveillance during which
patients are continuously monitored.
The Chinese trial will enrol
patients who have metastatic non-small cell lung cancer and for whom chemotherapy,
radiation therapy and other treatments have failed.
«Extremely hypofractionated
radiation therapy shows promising toxicity results for intermediate risk prostate cancer
patients.»
Early in the 20th century,
radiation therapy was also an emerging cancer treatment, and the nation's preeminent cancer pathologist, James Ewing, staunchly favored treating
patients with this promising new method.
Stamets furnished capsules of freeze - dried fungus for a seven - year, NIH - funded study by Bastyr University and the University of Minnesota to determine whether turkey tail mushrooms could help breast cancer
patients whose immune systems had been compromised by
radiation therapy.
Lead investigator, Evan Matros, MD, FACS, explained that today plastic surgeons are more willing to perform reconstructive procedures in these
patient groups — which include women age 65 and older or those who have had
radiation therapy — than they were 15 years ago, and that
patients themselves are more accepting of these reconstruction procedures.
Nearly half of all cancer
patients receive
radiation therapy to curb the growth of malignant cells.
Three
patient samples were positive for ALK — these
patients with peritoneal mesothelioma were women with no history of asbestos or
radiation therapy exposure.
This study used the National Cancer Data Base to analyze 9,817
patients and found that
patients treated at higher - volume facilities were more likely to have shorter
radiation therapy duration than those at lower volume facilities.
Of the 751
patients, 520 (69.2 %) received chemotherapy and
radiation therapy and 231 (30.8 %) received only
radiation therapy.
In our trial, however, the addition of
radiation therapy directed at each of the cancerous areas greatly improved how
patients responded to subsequent rounds of chemotherapy,» said Puneeth Iyengar, MD, PhD, lead author of the study and an assistant professor of
radiation oncology at the University of Texas Southwestern Medical Center in Dallas.
Knowing that this mutation may render
radiation ineffective,
patients could be spared that
therapy.
The study was a randomized phase II trial testing whether the addition of local treatment, in the form of consolidative
radiation therapy, to the standard treatment of systemic
therapy improved progression - free survival for
patients with limited metastatic NSCLC.
Patients with uveal melanoma receive surgery to remove the tumor — and in some advanced cases, the entire eye — as well as
radiation therapy or chemotherapy.
«There is a significant possibility that local
therapy, such as consolidative
radiation, may become an important part of the management of limited metastatic NSCLC
patients, but this validation must take place in randomized phase III studies.
Combining
radiation therapy with chemotherapy for
patients with limited metastatic non-small cell lung cancer (NSCLC) may curb disease progression dramatically when compared to NSCLC
patients who only receive chemotherapy, according to a new randomized phase II clinical trial reported today at the 59th Annual Meeting of the American Society for
Radiation Oncology (ASTRO).
Thirty - one lesions were treated with
radiation in the 14
patients that received local
therapy.
None of the recurrences among the latter
patients were in areas treated directly with
radiation therapy.
The other 200
patients were randomised to dose - escalated external beam
radiation therapy (DE-EBRT) and received an additional 32 Gy of external beam
radiation to achieve a total prostate dose of 78 Gy.
Trial # 1: A phase I / II trial of HCQ in conjunction with
radiation therapy and concurrent and adjuvant temozolomide in
patients with newly diagnosed glioblastoma multiforme
Hormone
therapies are used to treat prostate cancer
patients whose disease either isn't responding to
radiation or surgery or has already spread beyond the prostate gland.
The analysis compared
patient consultation rates with cancer specialists as well as treatment with surgery, chemotherapy and
radiation therapy for white and black
patients.
Such a molecule might also be able to ameliorate the side effects of chemotherapy or
radiation therapy of cancer
patients.
Two
patients that had previously not responded to available standard treatments, including surgery, external
radiation, hormonal and chemotherapy, have received 225Actinium - PSMA - 617 as experimental
therapy.
Twenty - two
patients with elevated prostate - specific antigen and biopsy - proven prostate carcinoma who underwent MRI of the prostate at 1.5 T with endorectal coil were divided into two groups: those who were treated with androgen deprivation,
radiation therapy, or both, and a Gleason - matched control group who had not received such
therapy.
Preliminary results of a study of
patients with prostate cancer show that MR tractography may be a reliable quantitative imaging biomarker to assess prostate cancer treatment response to androgen deprivation and
radiation therapy, according to a team of researchers at Brigham and Women's Hospital and Massachusetts General Hospital in Boston.
Since whole - brain
radiation is associated with significant cognitive effects and the use of additional
radiation therapy for progression is common in this population, the Yale researchers suspect that
patients with the ALK mutation would benefit from
radiation focused on individual metastases.
Regardless of disease stage,
patients who received surgery lived an average of 57 months, compared to less than 12 months for
patients who received only non-surgical treatment (such as chemotherapy or
radiation therapy), and 1.4 months for
patients who received no treatment at all.
The study showed that
patients who held their breath during
radiation therapy had only a 1.4 percent rate of ischemic heart disease after 8 years of follow up and an estimated rate of 3.6 percent after 10 years.
About 80 percent of
patients receiving high - dose, short - course
therapies had good cosmetic results, similar to longer - course treatments with smaller
radiation doses.