A sensitive and
specific radioimmunoprecipitation test was developed for the detection of antibodies to the major core protein of LAV, p25 (molecular weight 25,000).
The presence of antibodies to lymphadenopathy - associated retrovirus (LAV) was determined by
a radioimmunoprecipitation assay and by an enzyme - linked immunosorbent solid assay of sera from Zairian patients with the acquired immune deficiency syndrome (AIDS) in 1983.
Recently,
a radioimmunoprecipitation assay was developed to detect antibodies to recombinant canine glutamic acid decarboxylase and insulinoma antigen - 2 (84,85).