Sentences with phrase «radiotherapy resistance»

The goal of this center is to bring radiotherapy into the era of personalized medicine by identifying genetic markers of radiotherapy resistance and uncovering how heterogeneity within tumors affects radiotherapy efficacy.

Recently, tumorspheres derived from non-small cell lung cancer (NSCLC) cells showed altered DNA repair signalling possibly contributing to chemotherapy / radiotherapy resistance and subsequent maintenance of tumorigenicity [17].

Proteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome?

Not exact matches

Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence after treatment.

The Department of Translational Research hosts 5 technological platforms (Genomics, Protein arrays, High - content screening, Experimental radiotherapy and Preclinical investigation), 4 labeled teams (resistance to therapy in breast cancers, translational pediatrics, angiogenesis, and immunotherapy) and 3 emergent teams (Circulating biomarkers, uveal melanoma, and new targets in triple negative breast cancers).

Breast cancer cells, which survive in hypoxia, share many characteristics with breast cancer stem cells (CSC) such as loss of estrogen receptor - α (ER - α) expression (1), increased anoikis resistance (14) and increased resistance to radiotherapy and chemotherapy (15, 16).