It may also be caused by
random gene mutations that are completely unrelated to any physical trauma.
You are trying to say that a good figure of speech for purely
random gene mutations is «designed» really?
Not exact matches
The best model of what's happening is constrained randomness —
random mutation constrained to a sort of space of all possible functioning variations of the
gene.
There is the
random, that is purposeless,
mutation of
genes, and there is the mechanical selection among the resulting organisms by the environment.
In this paper, I tried to interpret evolution as a continually shifting balance, spatially and temporally, among what I called the pressures of
mutation, selection, and migration on
gene frequencies, in conjunction with the effects of
random drift composed of
random variations in these pressures and of local accidents of sampling.
= > In the atheist view there are only two agents of change in a populations
gene pool,
random mutation and natural selection.
In the carnivores, the bitter sensing
genes had slowly built up
random mutations that rendered many of them useless.
Now two groups working independently, reporting online May 24 in Nature, have compared samples from different times and locations to read the history recorded in
random mutations of the virus's 10
genes.
«Disrupting DNA repair will result in a storm of
random mutations, increasing the chance that the right
gene mutates at the right spot and lead to drug resistance.
Gene moonlighting can occur merely through changes in expression, which may result from as little as a single
mutation; it does not require the meandering process of
random alteration and selection implied by the duplication and neofunctionalization model.
If so, it could make cell fate more resilient to
random mutations in a plant's genetic code, even when such changes keep some
gene - regulating proteins from binding their intended DNA targets.
Sabeti's technique identifies versions of
genes that have been created by
random mutation and then retained — because they give their owners some natural advantage over individuals who do not have the
mutation.
Each
gene was found by
random germline mutagenesis, meaning
mutations were created in order to study resulting traits.
«The organization of cell colonies and phenotypic switching between different types of colonies becomes a lot more flexible and rapid with reversible aneuploidy than if it depended on
random mutations in the
genes,» Skupin says.
And while scientists have had some success in switching off
genes by inserting or deleting
random sequences, they have not yet been able to use CRISPR / Cas9 to paste in (or «knock in») specific new sequences to correct
mutations in T cells.
These
mutations are inserted into batches of yeast or bacterial cells, which express the altered
gene and produce millions of
random protein variants.
Chance chooses the
genes in which
random mutations show up; chance takes the fatal step in front of the crosstown bus.
Vogelstein also argued that the new research about
random mutations should offer comfort to people who develop cancer despite having «near - perfect lifestyles,» as well as to parents who are worried that they somehow «gave» their children cancer, either by passing on a harmful
gene or inadvertently exposing them to an environmental toxin.
Each
gene can be flicked on or off, and the switching mechanism is
random mutation within the switch region.
At some point in the past,
random mutations created a variant of one receptor
gene, located on the X chromosome, producing two different receptor types.
It is extremely difficult to demonstrate that such variants are actual
mutations affecting
genes, as they could simply be
random DNA changes that have a neutral effect.
But knocking out specific
genes, or creating
random genetic
mutations using chemicals like EMS, and examining the results are approaches that «have been done to death,» says Martin Yanofsky, of the University of California, San Diego, in La Jolla.
Due to
random mutation or the wide
gene pool, cats of any color can be born deaf (probably less than 1 %)- including orange - eyed whites.
The show takes its cue from «FOXP2», the
gene that made the development of speech and language possible due to a single,
random mutation around 10,000 years ago.