His work with these groups, funded by NIMH, NIDA, the Annie E. Casey Foundation, and others, spans all phases of treatment research, including initial development and pilot testing of intervention protocols,
randomized efficacy studies, and multi-site effectiveness trials.
Not exact matches
Last year The Ohio State University Wexner Medical Center began clinical trials on the
efficacy of SuperBetter to treat traumatic brain injuries, and the University of Pennsylvania Positive Psychology Center greenlighted a
randomized controlled user
study of the game to treat depression.
[1] Lugo JP, et al. «
Efficacy and tolerability of an undenatured type ll collagen supplement in modulating knee osteoarthritis symptoms: a multicenter
randomized, double - blind, placebo - controlled
study.»
For the same reason, it is not easy to prove treatment
efficacy by means of controlled,
randomized studies, the «gold standard» for evaluating new therapies.
The
randomized study, working with 1,345 third to fifth graders (8 - 11 year olds) in nine US elementary schools, assessed the
efficacy of a three - year programme.
«
Randomized trials have confirmed the value of radiation dose escalation for prostate tumors, and the potential benefits of larger radiation doses in fewer fractions, are expected to increase the therapeutic
efficacy for men with prostate cancer,» said Anders Widmark, MD, a professor of radiation sciences at Umeå University in Umeå, Sweden and lead author of the
study.
The new
study was a prospective,
randomized, investigator - blinded
study that included more than 250 daptomycin - exposed children, ages 1 to 17, to document safety and
efficacy of the antibiotic in treating pediatric skin and skin structure infections.
The determination of each
efficacy level was also based on the rigor and quantity of published
studies on the drug class: to be in Level A, for example, a class of drugs must have been supported by at least two «Class I»
studies — well - designed, double - blind,
randomized, placebo - controlled clinical trials.
He also believes that additional research — possibly
randomized, prospective
studies — should be done to compare the safety and
efficacy of PAE with other commonly performed BPH treatments.
A Phase III, Open Label,
Randomized Study to Assess the
Efficacy and Safety of Olaparib (Lynparza) versus Enzalutamide or Abiraterone Acetate in Men with Metastatic Castration - Resistant Prostate Cancer who have Failed Prior Treatment with a New Hormonal Agent and have Homologous Recombination Repair Gene Mutations.
A Phase 3,
Randomized, Open - Label
Study Evaluating the
Efficacy of Axicabtagene Ciloleucel versus Standard of Care Therapy in Subjects with Relapsed / Refractory Diffuse Large B Cell Lymphoma (ZUMA - 7)
REFLECT is a multi-center,
randomized, double - masked, placebo - controlled
study to evaluate the safety and
efficacy of bilateral injections of GS010 in subjects with LHON due to the NADH dehydrogenase 4 (ND4) mutation.
METHODS: Three hundred seventy - two patients with mild to moderate AD were
randomized to receive IM injections of AN1792 or placebo (4:1) at baseline and at months 1, 3, 6, 9, and 12 in a multicenter Phase II safety, tolerability, and pilot
efficacy study.
FORWARD1: A
Randomized, Open Label Phase 3
Study to Evaluate the Safety and
Efficacy of Mirvetuximab Soravtansine (IMGN853) Versus Investigator's Choice of Chemotherapy in Women with Folate Receptor Alpha - Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer
The
efficacy of the elimination phase of the low - FODMAP diet for overall gastrointestinal symptom relief in adult patients with IBS has been seen in
randomized, controlled trials; a blinded,
randomized, rechallenge
study; and observational
studies that have been reviewed in detail elsewhere
Dominguez - Munoz JE, Iglesias - Garcia J, Iglesias - Rey M, Figueiras A, Vilarino - Insua M. Effect of the administration schedule on the therapeutic
efficacy of oral pancreatic enzyme supplements in patients with exocrine pancreatic insufficiency: a
randomized, three - way crossover
study.
, A
randomized, double - blind placebo - controlled
study on acceptability, safety and
efficacy of oral administration of sacha inchi oil (Plukenetia volubilis L.) in adult human subjects, 2014
A Controlled, Double - Blind,
Randomized Study on the
Efficacy of Lactobacillus Plantarum 299V in Patients with Irritable Bowel Syndrome; European Journal of Gastroenterology & Hepatology; October 2001; Volume 13; Issue 10 - pp 1143 - 1147
Efficacy studies summarize findings from quasi-experimental and
randomized controlled trials to provide statistical evidence of the effectiveness of Apex Learning.
This
randomized controlled
study investigates the impact of a Facing History and Ourselves professional development intervention on high school teachers» sense of professional
efficacy, satisfaction, and growth of their students» engagement and learning.
He has been PI of many research grants where
randomized controlled trials and single subject design
studies have been used to investigate the
efficacy of a variety of practices that integrate VP academic strategies, ET, and methods to address behavioral problems.
A
randomized controlled
study with 9th and 10th grade students in 60 high schools has proven the
efficacy of the materials provided by Facing History and Facing Ourselves:
Information regarding the theoretical foundations of MF - PEP has been published previously.21 Pilot
studies indicate that MF - PEP is associated with the following: increased knowledge of mood disorders; increased positive family interactions; increased
efficacy in seeking treatment; improved coping skills; improved parental attitude toward the child and the treatment; increased social support from parents; and a trend toward increased social support from peers in children.22, 23 To assess the impact of MF - PEP on children's mood symptoms, this full - scale
randomized trial was conducted.
Investigating the
efficacy of an individualized metacognitive therapy program (MCT +) for psychosis:
study protocol of a multi-center
randomized controlled trial.
OSLC conducted a
randomized efficacy trial of KITS 2005 - 2010 and a follow - up
study 2010 - 2015.
In addition, Dr. Kim is closely involved in two
randomized control
efficacy studies to test effects of the Kids in Transition to School (KITS) program which was designed to increase school readiness among at - risk populations including children in foster care.
This
study (NIDA #R01DA025616) is a
randomized clinical trial (RCT) that will compare an experimental treatment (OutPatient Treatment for Adolescents) to an «active placebo» on key indices (drug use; mental health; behavioral, school, peer, and family functioning; and consumer satisfaction) from pre-treatment through 18 months in order to evaluate its
efficacy for youth referred to outpatient treatment of co-occurring substance use and internalizing problems.
The
efficacy of the FTI has been
studied in comparison with a lecture intervention for parents in a
randomized setting in the USA [2, 4, 7].
Summary: (To include comparison groups, outcomes, measures, notable limitations) The
study examined the
efficacy, speed, and incidence of symptom worsening for subjects
randomized to 3 treatments of PTSD: Prolonged Exposure, relaxation training, or Eye Movement Desensitization and Reprocessing (EMDR).
Summary: (To include comparison groups, outcomes, measures, notable limitations) This
study tested the
efficacy of the Chicago Parent Program (CPP) utilizing data from two prevention
randomized trials that were merged to compare its effects for African - American versus Latino parents and their preschool children for reducing behavior problems and increasing parenting skills.
Although several (meta - analytic reviews of)
randomized studies emphasize the
efficacy of mindfulness - based interventions in adults (e.g., Baer 2003; Grossman et al. 2004; Hofmann et al. 2010; Segal et al. 2002),
studies of mindfulness training in adolescents are still in its infancy (Burke 2009; Greco and Hayes 2008).
She has been Primary Investigator or methodologist of 2
randomized controlled trials testing the
efficacy of EFT for co-occurring depression and relationship discord, and of a recent NIMH funded
study aimed to personalize treatment for depression.
The Kids in Transition to School (KITS)-- Developmental Disabilities Follow - Up is a longitudinal
study of the effects of a
randomized efficacy trial of a preventive intervention to enhance psychosocial and academic school readiness in children with developmental disabilities and behavior or social difficulties who were entering kindergarten.
The current
study is the first
randomized - controlled trial evaluating the feasibility an initial
efficacy of an 8 - week outpatient Mindfulness - Based Relapse Prevention (MBRP) program as compared to treatment as usual (TAU).
Dr. Clark has been Principal Investigator and Co-Investigator on numerous NIH funded
studies including a
randomized clinical trial examining the
efficacy of a mother - infant relational approach for women experiencing major depression in the postpartum period and another investigating the validity of screening and assessment measures of social - emotional functioning in infants and young children.
Abstract: The aim of this
randomized controlled
study is to explore the long - term
efficacy of the widely used Triple P parent group training as a universal prevention intervention.
The
study involves data collection with a subsample of 9 — 13 year - old children who participated in a
randomized efficacy trial of Treatment Foster Care of Oregon for Preschoolers (TFCO - P).
The aim of this
randomized controlled
study is to explore the long - term
efficacy of the widely used Triple P parent group training as a universal prevention intervention.
This
study uses data from a
randomized clinical trial testing the
efficacy of Familias Unidas + Parent — Adolescent Training for HIV Prevention (PATH), an ecodevelopmental, parent - centered intervention, in preventing unsafe sexual behavior in Hispanic adolescents (Krauss et al., 2000; Pantin et al., 2004).
The
study was a
randomized controlled trial evaluating the
efficacy of a brief and preventatively - focused parenting discussion group for dealing with disobedient behavior in preschool - aged children.
In a small
randomized pilot
study, the
efficacy of MOSAIC was tested in a sample of 24 children with ADHD participating in a 2 - week summer day camp with 113 typically developing peers.
This
study aimed to evaluate the
efficacy of the Fun to Learn for the Young (FLY) program using
randomized controlled trial design with no blinding of participants.