According to a report from the National Cancer Institute, a study of 30
randomized studies found that THC (the active ingredient in marijuana) extracts outperformed traditional anti-nausea drugs and helped patients gain weight.
The researchers note that a recent systematic analysis of
randomized studies found that donor milk as a supplement to mother's milk did however reduce the risk of necrotizing enterocolitis, a severe gastrointestinal emergency.
Not exact matches
The most recent
findings of the Belarus
study (an excellent, large scale,
randomized, first world
study) were recently published and show that 11 year - olds have a 17 % GREATER chance of being obese or overweight if they were in the breastfeeding group than in the control group.
In 2007, researchers published the first
randomized, controlled
study of the effect of being raised in an orphanage; that
study, and subsequent research on the same sample of Romanian orphans,
found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional development.
Primarily because we do not
find the same benefits in better - designed
studies — sibling comparison
studies and the PROBIT
randomized controlled trial.
Comparing the Kangaroo care method with standard incubator care, a
randomized control
study published in the magazine «Annals of Tropical Pediatrics»
found that the former is by far superior.
However, three
studies have
randomized (Rienks et al., 2011, Besnard et al., 2009, Cowan et al., 2009) and all have
found benefits from couple - participation.
The
study started as an RCT in 2006, but was changed into a prospective cohort
study in 2007 because it was impossible to
find women who would agree to be
randomized for place of birth [12].
A 2005 meta - analysis of six
randomized control trials (the gold standard for medical
studies)
found that nipple stimulation increases the likelihood of labor.
Although not directly comparable, our
findings are in broad agreement with those from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our
findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster
randomized trial in Belarus (PROBIT)
found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational
study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.
Research shows that families typically receive roughly half of the number of home visits expected.16, 17 For example, across three
randomized controlled trials conducted of Nurse Family Partnership, average dosage of visits ranged from 45 to 62 percent.18 Research also shows that many, perhaps most, families enrolled in home visiting programs drop out before their eligibility ends.16, 19,20 Some home visiting
studies have varied the dosage that families were offered and
found that fewer home visits produced outcomes similar to higher levels of exposure.21
Studies of the Nurse Family Partnership model followed children to 6 years and
found significant program effects on language and cognitive functioning as well as fewer behaviour problems in a
randomized controlled trial
study.24 In addition, more recent evaluations of Healthy Families America have shown small, but favourable effects on young children's development.25, 26
One
randomized controlled trial comparing home - visited families with control participants who received other community services
found a statistically significant difference in mean depressive symptoms at two years post-enrollment, but this contrast was nonsignificant at three years post - enrollment.15 A second
study of Early Head Start
found no differences in depressive symptoms between intervention and control group participants post-intervention, although a difference was detected at a longer - term follow - up prior to children's enrollment in kindergarten.10 Other
randomized controlled trial
studies have not
found effects of home visitation on maternal depressive symptoms.12, 16,17
A series of
randomized control trials of a nurse home visitation program show a range of positive effects on maternal health, including decreases in prenatal cigarette smoking, fewer hypertensive disorders in pregnancy, and fewer closely spaced subsequent pregnancies., A
randomized control
study of another program that works with a particularly high - risk population
found that participant mothers showed significantly lower depressive symptoms than those in the control group and were less likely to report feeling stressed a year after participation.
Already, she and her collaborator, Julie Mennella, have confirmed the
finding of a previous
study that
found that healthy babies
randomized to receive cow's milk formula had accelerated weight gain compared to babies fed a hydrolyzed protein formula (a formula typically for infants with cow's milk allergy), who gained weight similarly to their breastfed counterparts.
In a secondary analysis of a multicenter
randomized study of fetal pulse oximetry, of 4,126 nulliparous women who reached the second stage of labor, none of the following neonatal outcomes was
found to be related to the duration of the second stage, which in some cases was 5 hours or more: 5 - minute Apgar score of less than 4, umbilical artery pH less than 7.0, intubation in the delivery room, need for admission to the neonatal intensive care unit, or neonatal sepsis (27).
A multicenter,
randomized control
study found that babies born in hospitals whose policies promoted exclusive breastfeeding were significantly more likely to be exclusively breastfed at six months.
In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review
found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational
studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter,
randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.
Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have
found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed
randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1
study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.
However, a
randomized study is needed to confirm these
findings, according to the authors.
In a
study to be presented Thursday, Jan. 26, in the oral concurrent session at 1:15 p.m. PST, at the Society for Maternal - Fetal Medicine's annual meeting, The Pregnancy Meeting ™, researchers with the Albert Einstein College of Medicine / Montefiore Medical Center in Bronx, New York, will present their
findings in a
study titled, Comparison of subcuticular suture type in post-cesarean wound complications: a
randomized controlled trial.
It's important to note that
randomized studies haven't
found side effects even remotely as prevalent as critics contend.
The researchers write that a large - scale, controlled and
randomized study should be conducted to validate their
findings.
The
findings, which come from a
study of 678 women in a
randomized breastfeeding trial who were recruited at mid-pregnancy, question whether recommendations to avoid bed - sharing due to concerns such as sudden infant death syndrome (SIDS) may impede some women from achieving their breastfeeding goals and could thereby prevent women and their children from experiencing all of the short - and long - term benefits of breastfeeding.
In a
study to be presented Thursday, Jan. 26, in the oral concurrent session at 1:15 p.m. PST, at the Society for Maternal - Fetal Medicine's annual meeting, The Pregnancy Meeting ™, researchers with the Université de Sherbrooke in Sherbrooke, Quebec, Canada will present their
findings in a
study titled, Reduction of total labor length through the addition of parenteral dextrose solution in induction of labor in nulliparous: results of DEXTRONS prospective
randomized controlled trial.
The
study, published in the journal PLoS ONE,
found that a majority of smokers and nonsmokers who responded to a
randomized telephone survey said they supported increasing warning sizes to cover 25 percent, 50 percent, and as much as 75 percent of cigarette packs.
Researchers
found that in most cases the number of
randomized studies involving medical cannabis is extremely limited or entirely absent.
«While
randomized clinical trials are needed to test whether this is a causal relationship, these
findings indicate doctors should consider using or re-starting ACEIs and ARBs as first - line blood pressure medications for patients undergoing peritoneal dialysis,» said Jenny I. Shen, MD, an LA BioMed researcher and corresponding author of the
study.
Examining more than 100 peer - reviewed
studies of predator control, the
study found not a single lethal control
study that met scientists» gold standard: a
randomized, controlled design.
A
randomized phase III trial
finding that a new monoclonal antibody, elotuzumab, added to standard therapy, extended the duration of remission for patients with relapsed multiple myeloma by about five months
Findings from two phase III
studies showing that children with Wilms tumor who have a specific chromosomal abnormality do better with a more intensive, augmented chemotherapy regimen
Motivated by their previous
finding of the presence of P - glycoprotein overexpression in the nasal lining of patients with CRS with nasal polyps, the
study authors conducted a
randomized, double - blind, placebo - controlled clinical trial
studying the use of low - dose Verapamil in 18 patients with CRS with nasal polyps.
«Our
findings highlight the potential value for a
randomized controlled trial of aspirin as an agent in early detection of breast cancer, particularly for women with naturally dense tissues who may be at an increased risk for certain cancers,» said Despina Kontos, PhD, assistant professor of Radiology, and co-author on the
study.
The
findings of the
randomized study (S6 - 03) were presented at the 2014 San Antonio Breast Cancer Symposium, held Dec. 6 - 9, by Dr. Kerin Adelson, assistant professor of medical oncology at Yale Cancer Center and chief quality officer at Smilow Cancer Hospital at Yale - New Haven.
In the 1980s, both US - based and international
randomized clinical
studies found that BCT and mastectomy offered women with early stage breast cancer equal survival benefit.
In a
randomized clinical
study involving adults age 56 to 71 that recently published in Neurobiology of Aging, researchers
found that after cognitive training, participants» brains were more energy efficient, meaning their brain did not have to work as hard to perform a task.
One 2008
study, for instance, analyzed 16 papers investigating publication bias in
randomized clinical trials and
found clear indications of selective publication.
An analysis of more than 600 class I (procedure / treatment should be performed / administered) American College of Cardiology / American Heart Association guideline recommendations published or revised since 1998
finds that about 80 percent were retained at the time of the next guideline revision, and that recommendations not supported by multiple
randomized studies were more likely to be downgraded, reversed, or omitted, according to a
study in the May 28 issue of JAMA.
«The
finding from this observational
study that women who underwent menopause at a later age and used oral hormone therapy had greater hearing loss was unexpected but should lead to more testing in a
randomized, clinical trial,» says Dr. JoAnn Pinkerton, NAMS executive director.
In what appears to be the first
randomized controlled
study in this cohort, researchers
found that 600 IUs did not restore what many experts consider the optimal blood level of vitamin D within 16 weeks.
A
study published in The New England Journal of Medicine (NEJM) in 2001
found no survival benefit for the 158 women
randomized to support groups compared with the 77 women who were not enrolled in the groups.
«We were surprised to
find that few
randomized trials have successfully changed what people think and feel about vaccines, and those few that succeeded were minimally effective in increasing uptake,» the
study said.
Similarly the epilepsy
studies, including a single
randomized trial,
found that medical cannabis reduced the frequency of seizures in participants, some with treatment - resistant seizures.
A systematic review of published
studies on the use of medical cannabis in children and adolescents
finds a notable lack of
studies and a minimal number of the
randomized, controlled trials needed to confirm the effectiveness of a treatment.
The
study was the first
randomized - controlled trial to examine the potential benefits of the low fat diet on the management of MS.. The
study found no significant differences between the two groups in brain lesions detected on MRI brain scans or on other measures of MS.. But while the number of trial participants was relatively small,
study leaders believe the significantly improved fatigue symptoms merited further and larger
studies of the diet.
The trials for chemotherapy side effects — 4 of which were
randomized controlled trials —
found that medical cannabis was significantly better than anti-nausea drugs standard at the time of
study for reducing nausea and vomiting.
In the second
study, «High - intensity versus Low - intensity Rehabilitation after Total Knee Arthroplasty: A
Randomized Controlled Trial,» researchers
found that activating and exercising the quadriceps muscles as soon as possible after TKR may be the key to regaining optimal, post-surgical function in the knee and legs.
The Physicians» Health
Study II (PHS II) remains the only
randomized, large - scale, long - term trial to test whether a daily multivitamin reduced cardiovascular disease risk, and researchers
found that after 11 years of follow up, there was no significant difference in risk of major cardiovascular disease (CVD) events among men who took a multivitamin compared to those that took a placebo.
Already, she and her collaborator, Julie Mennella, have confirmed the
finding of a previous
study that
found that healthy babies
randomized to receive cow's milk formula had accelerated weight gain compared to babies fed a hydrolyzed protein formula (a formula typically for infants with cow's milk allergy), who gained weight similarly to their breastfed counterparts.
To
find out, they
randomized a total of 719 patients between 25 and 35 days after liver transplant into three
study arms.
This Phase 3
randomized, double - blind
study included 763 adults with chronic HCV genotype 1 infection, a form of the virus
found in up to 75 percent of infections, and compensated liver diseases, who had previously not responded or only partially responded to at least one course of peginterferon and ribavirin.