A randomized study comparing the effects of a low - carbohydrate diet and a conventional diet on lipoprotein subfractions and C - reactive protein levels in patients with severe obesity.
A prospective
randomized study comparing hCG, vaginalmicronized porgesterone and a combination regimen for luteal phase support in an in - vitro fertilization programme [abstract].
Geusa S, Causio F Marinaccio M Stanziano A Sarcina E. Luteal phase support with progesterone in IVF / ET cycles: a prospective,
randomized study comparing vaginal and intramuscular administration [abstract].
I was just at the annual nutrition conference hosted by the Physician's Committee for Responsible Medicine (PCRM) a month ago in DC, and heard a presentation of a fascinating study where they did
a randomized study comparing 2 vs. 6 meals per day for 12 weeks, with the exact same number of total calories consumed, and then they did a «crossover», where the people eating 2 meals switched to 6 meals and vice versa.
PHIII
Randomized Study Comparing Perioperative Nivolumab vs. Observation in Patients with Localized Renal Cell Carcinoma Undergoing Nephrectomy.
Researchers analyzed data from over 5,000 men from three
randomized studies comparing HRT with CRT in men with prostate cancer.
Not exact matches
In a
study at the University of the Philippines, researchers used a
randomized cross-over design to
compare the effects on blood glucose of brown rice and white rice on 10 healthy and nine Type 2 diabetic volunteers.
Static stretching neither prevented or induced injury when
compared to not stretching before running, according to the results of a first - of - its - kind large scale
randomized study presented at the 2011 Annual Meeting of the American Academy of Orthopaedic Surgeons in San Diego.
In 2007, researchers published the first
randomized, controlled
study of the effect of being raised in an orphanage; that
study, and subsequent research on the same sample of Romanian orphans, found that
compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional development.
Comparing the Kangaroo care method with standard incubator care, a
randomized control
study published in the magazine «Annals of Tropical Pediatrics» found that the former is by far superior.
In the only controlled,
randomized scientific
study to
compare graduated extinction and «positive routines» head - to - head, there were no significant differences in treatment outcomes for kids (Adams and Rickert 1989).
As with neurobehavior, effects on breastfeeding are poorly
studied, and more recent
randomized controlled trials
comparing exposure to epidural and opiate drugs are especially misleading because opiates have a well - recognized negative effect on early breastfeeding behavior and success.103 — 107
One
randomized controlled trial
comparing home - visited families with control participants who received other community services found a statistically significant difference in mean depressive symptoms at two years post-enrollment, but this contrast was nonsignificant at three years post - enrollment.15 A second
study of Early Head Start found no differences in depressive symptoms between intervention and control group participants post-intervention, although a difference was detected at a longer - term follow - up prior to children's enrollment in kindergarten.10 Other
randomized controlled trial
studies have not found effects of home visitation on maternal depressive symptoms.12, 16,17
Already, she and her collaborator, Julie Mennella, have confirmed the finding of a previous
study that found that healthy babies
randomized to receive cow's milk formula had accelerated weight gain
compared to babies fed a hydrolyzed protein formula (a formula typically for infants with cow's milk allergy), who gained weight similarly to their breastfed counterparts.
The aim of this
study was to evaluate adherence to the Neonatal Resuscitation Program algorithm by subjects working from memory as
compared to subjects using a decision support tool that provides auditory and visual prompts to guide implementation of the Neonatal Resuscitation Program algorithm during simulated neonatal resuscitation.Healthcare professionals (physicians, nurse practitioners, obstetrical / neonatal nurses) with a current NRP card were
randomized to the control or intervention group and performed three simulated neonatal resuscitations.
A more helpful
study would
randomize women to elective induction or spontaneous labor and then
compare subsequent postpartum mood disorders.
This
study used a
randomized controlled double - blinded design to determine the functional recovery effects of wearing below - knee compression socks
compared with placebo noncompressive below - knee socks.
Most
studies attempt to circumvent this by using
randomized experimentation, usually
comparing reactions, preferences with identical fictional candidates, varying only race / ethnicity / gender.
When the researchers gave concentrated broccoli sprout extracts to 97 human type 2 diabetes patients in a 12 - week
randomized placebo - controlled trial, obese participants who entered the
study with dysregulated disease demonstrated significantly decreased fasting blood glucose levels
compared to controls.
The
study, called the Bypass Surgery Versus Everolimus - Eluting Stent Implantation for Multivessel Coronary Artery Disease (BEST) trial, is one of only two
randomized controlled trials to
compare bypass to angioplasty since the introduction of everolimus - eluting stents, a new generation of drug - eluting stent.
However, prior to this
study there has been a lack of
randomized controlled trials with a long - term follow - up that
compare the effectiveness of noninvasive treatments.
Another problem is that modeling
studies, like this one, are inherently less powerful than other kinds of medical research:
randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control
studies, which
compare patients who have a condition with those who do not; or cohort
studies, which determine the risk of contracting a disease by
studying a group of people with similar demographics.
In devising their experiment, the researchers took advantage of ambulance company practices that essentially provided a
randomized group of patients to
study, making it possible to
compare outcomes at different hospitals.
The benefit assessment of radium - 223
compared with BSC was the
randomized controlled approval
study BC1 06 (ALSYMPCA).
The benefit assessment was based on two
randomized controlled approval
studies (MALACHITE I and II), in which ombitasvir / paritaprevir / ritonavir in combination with dasabuvir and / or ribavirin was directly
compared with triple therapy consisting of telaprevir, pegylated interferon and ribavirin.
The benefit assessment was based on two
randomized controlled approval
studies (MALACHITE I and II), in which dasabuvir in combination with ombitasvir / paritaprevir / ritonavir and / or ribavirin was directly
compared with triple therapy consisting of telaprevir, pegylated interferon and ribavirin.
In a
randomized, phase 2 multi-center clinical
study, led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone
compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutations.
This
study compared pregnancy outcomes among 292 women
randomized to either receive heparin or not.
A
study published in The New England Journal of Medicine (NEJM) in 2001 found no survival benefit for the 158 women
randomized to support groups
compared with the 77 women who were not enrolled in the groups.
The original,
randomized, open label
study, which enrolled 20 outpatient men with cirrhosis and recurrent HE receiving standard - of - care (SOC) treatment, had previously reported that a single FMT enema after antibiotic pretreatment improved cognitive function at Day 20 and reduced HE episodes and hospitalizations over the following 5 months
compared with SOC.1 The long - term outcomes of this
study, which were presented today at The International Liver Congress ™ 2018 in Paris, France, demonstrated sustained and statistically significant reductions in the number of HE episodes and hospitalizations as well as improvements in cognitive function over 1 year in the men who received FMT
compared with the control group.
The Physicians» Health
Study II (PHS II) remains the only
randomized, large - scale, long - term trial to test whether a daily multivitamin reduced cardiovascular disease risk, and researchers found that after 11 years of follow up, there was no significant difference in risk of major cardiovascular disease (CVD) events among men who took a multivitamin
compared to those that took a placebo.
Already, she and her collaborator, Julie Mennella, have confirmed the finding of a previous
study that found that healthy babies
randomized to receive cow's milk formula had accelerated weight gain
compared to babies fed a hydrolyzed protein formula (a formula typically for infants with cow's milk allergy), who gained weight similarly to their breastfed counterparts.
Study participants (n = 146; 101 males, 45 females) were enrolled in a 16 - week
randomized clinical trial
comparing naltrexone with placebo treatment.
He also believes that additional research — possibly
randomized, prospective
studies — should be done to
compare the safety and efficacy of PAE with other commonly performed BPH treatments.
The LowSALT CKD
study represents the first blinded
randomized controlled trial
comparing a high vs low salt intake in people with CKD.
In this
study, to our knowledge the largest
randomized clinical trial of robotic - assisted laparoscopic surgery for patients with rectal adenocarcinoma suitable for curative resection, there were no statistically significant differences in the rates of conversion to open laparotomy for robotic - assisted laparoscopic surgery
compared with conventional laparoscopic surgery (8.1 % vs 12.2 %, respectively), and there were no statistically significant differences in CRM +, complication rates, or quality of life at 6 months.
«Among those we
studied who were
randomized to the diet and exercise intervention, it was found that they were 15 percent less likely to develop knee pain
compared with their counterparts
randomized to the control condition.»
Effectiveness of blood flow restricted exercise
compared with standard exercise in patients with recurrent low back pain:
study protocol for a
randomized controlled trial.
The only
randomized study of adjuvant chemotherapy in mucosal melanoma demonstrated significantly increased relapse - free and overall survival in patients receiving temozolomide and cisplatin, as
compared with interferon alfa - 2b or observation.
The Retreat and Relaxation
Study, a
randomized trial,
compared the effects of vacation at a resort to training in a meditation / yoga retreat at the same resort (La Costa Resort and Spa).
The validation cohort consisted of 99 patients enrolled in two prospective
studies (NCT 01746992 and NCT 02533700,
randomized trials to
compare CHOP - based chemotherapy with sequential chemotherapy with CEOP / IVE / GDP or CTOP / ITE / MTX).
5/21/2007 Nationwide
Study Compares Surgeries to Treat Urinary Incontinence in Women The University of California, San Diego Medical Center along with nine other clinical research institutions across the United States has completed the largest
randomized clinical trial to date
comparing two commonly performed surgical procedures to t...
The U.S. drug maker released a statement on Monday saying that its Keynote - 010
study, a
randomized Phase two - third trial, showed that patients who were taking two different doses of Keytruda (FDA - approved two mg / kg dose and treatment dose of 10 mg / kg given every three weeks) had longer survival
compared to those who took docetaxel, the drug widely used for non-small cell lung cancer (NSCLC).
The expert review panel recommended one practice guideline based on a 2005
randomized trial that provided data to support a memory retraining protocol.12, 13 The trial enrolled 29 subjects with MS - related learning deficits and
randomized them to either the control group (n = 14) or the experimental group (n = 15).13 Both groups participated in 8 «treatment» sessions, which consisted of nontraining memory tasks for the control group and the Story Memory Technique (SMT), which taught the skills of visualization and context to improve learning, for the experimental group.13 In subjects with moderately severe impairment, 88 % in the experimental group showed significant improvement in learning abilities
compared with 38 % in the control group (P <.01).13 Subjects with mild impairment showed little improvement.13 On this basis, the technique used in this
study was recommended by the review panel as a practice guideline for the rehabilitation of learning and memory in persons with MS. 12
Another
randomized, double - blind placebo
study found that those who took zinc acetate lozenges had a significantly shorter duration of a cold
compared to those who took a placebo.
A systematic review of 17,
randomized controlled trials found 11
studies that linked regular yoga practice to significantly greater reductions in systolic BP
compared to pharmacotherapy, breath awareness, health education, no treatment, or usual care.
In the most recent
study published in Gynecological Endocrinology, a
randomized double - blind clinical trial involving 94 women with PCOS
compared NAC 600 mg, three times a day with 500 mg oral metformin, three times a day for 24 weeks.
In one such
randomized, double - blind, cross-over
study involving 22 subjects, a high monounsaturated diet that emphasized peanuts and peanut butter decreased cardiovascular disease risk by an estimated 21 %
compared to the average American diet.
Two prospective
randomized studies have
compared hormones with controls.
Bray also discusses the fact that sweetened beverages in general, as
compared to sweeteners added to solid foods, have a greater tendency to cause weight gain, citing a
randomized, double - blind European
study by Rabin and others, which found that drinking calorically sweetened beverages resulted in greater weight gain over the ten - week
study than did drinking diet drinks.8 Since the beverages in this
study were sweetened with sucrose, Bray called for a second
randomized controlled
study to
compare sucrose - and HFCS - sweetened beverages.