A large,
randomized study led by a UNC Lineberger Comprehensive Cancer Center researcher found that vitamin D and calcium supplements do not reduce the risk of colorectal adenomas, which are benign tumors that can evolve into colorectal cancer.
Not exact matches
«
Randomized trials have confirmed the value of radiation dose escalation for prostate tumors, and the potential benefits of larger radiation doses in fewer fractions, are expected to increase the therapeutic efficacy for men with prostate cancer,» said Anders Widmark, MD, a professor of radiation sciences at Umeå University in Umeå, Sweden and
lead author of the
study.
The REACT (
Randomized Evaluation of an Algorithm for Crohn's Treatment)
study,
led by Robarts Clinical Trials at Western University (London, Canada) provides valuable new insights for community gastroenterologists which should benefit patients.
The epidemiological evidence was strong enough that it
led to a whole series of clinical
studies and
randomized control trials with fish oil, says nutritionist Penny M. Kris - Etherton of Pennsylvania State University.
What sets the
study apart from most previous evaluations is its
randomized, controlled design — a relatively new approach honed by
lead author Abhijit Banerjee, an economist at the Massachusetts Institute of Technology in Cambridge, and his colleagues.
«This is the first
study to show that a systemic therapy provides significant clinical benefit in a
randomized fashion to advanced uveal melanoma patients, who have very limited treatment options,» said Richard D. Carvajal, MD, a medical oncologist at Memorial Sloan - Kettering and
lead author on the
study.
The new six - year
study, «Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18 - month
randomized clinical trial,» involved 54 adults and was
led by Shaun Eack, Ph.D., M.S.W., Pitt's David E. Epperson Professor of Social Work and Psychiatry, and Nancy Minshew, M.D., Pitt professor of psychiatry and neurology.
In a
randomized, phase 2 multi-center clinical
study,
led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutations.
«The finding from this observational
study that women who underwent menopause at a later age and used oral hormone therapy had greater hearing loss was unexpected but should
lead to more testing in a
randomized, clinical trial,» says Dr. JoAnn Pinkerton, NAMS executive director.
The researchers also want to add to this current observational
study to establish, through
randomized controlled trials, that eating fish can
lead to better sleep, better school performance and other real - life, practical outcomes.
«We have completed four
randomized studies, and they have
led us to conclude that Aged Garlic Extract can help slow the progression of atherosclerosis and reverse the early stages of heart disease.»
This
study has been published in the Neuroimage journal and is part of the ActiveBrains project, which is a
randomized clinical trial involving more than 100 overweight / obese children
led by Francisco B. Ortega.
«While the results of this
study are preliminary, they hold promise for enhancing and maintaining brain reserve in later life, particularly among sedentary individuals who may benefit most urgently from behavioral interventions like Experience Corps,» said Carlson, who is now
leading a larger fMRI trial as part of a large - scale
randomized trial of the Baltimore Experience Corps Program.
A Multicenter,
Randomized, Open - label, 3 - Arm Phase 3
Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan / Cetuximab or Infusional 5 - Fluorouracil (5 - FU) / Folinic Acid (FA) / Irinotecan (FOLFIRI) / Cetuximab with a Safety
Lead - in of Encorafenib + Binimetinib + Cetuximab in Patients with BRAF V600E - mutant Metastatic Colorectal Cancer
The LEAP
study, designed and conducted by the ITN with additional support from FARE and
led by Professor Gideon Lack at Kings College London, is the first
randomized trial to prevent food allergy in a large cohort of high - risk infants.
«While evidence from a recently completed [
randomized controlled trial] suggested that statin use is of little benefit to COPD patients, this population - based analysis showed that statin use reduced all - cause mortality among COPD patients,» wrote the
study authors
led by Adam Raymakers, from the University of British Columbia.
«It has been proposed, mainly on the basis of observational
studies, that nuts may provide superior satiation, may
lead to reduced calorie consumption,... but evidence from
randomized, interventional
studies is lacking.»
Likewise, a large meta - analysis
study of 10
randomized, double - blind
studies found that on average, chromium
led to a 1.1 kg loss in weight [6].
A multicenter
randomized controlled trial of a plant - based nutrition program to reduce body weight and cardiovascular risk in the corporate setting: the GEICO
study finds no calorie restrictions
led to weight loss.
As befitting an article published in the nation's
leading statistics journal, it introduces new statistical techniques to deal with problems that often emerge in
randomized field trials: 1) missing data (for instance, not all students who initially joined the
study participated in the follow - up testing sessions), and 2) noncompliance (some students, for example, refused the vouchers that were offered to them).
She
leads a number of
studies that evaluate education programs using rigorous econometric methods, including
randomized control trials, propensity score matching methods, and other quasi-experimental evaluation designs.
A new, three - year
randomized control
study of Milwaukee (WI) Public Schools from Johns Hopkins and Old Dominion Universities has found that students in schools
led by principals who graduated from the National Institute for School Leadership's (NISL) Executive Development Program (EDP) outperformed their peers in math and literacy on state assessments.
First, while the Perry Preschool results are based on a
randomized design, the CPC
study,
led by Arthur Reynolds and Judy Temple, used a quasi-experimental group without a pre-test for major outcome variables.
The team at University of Georgia,
led by Budsberg,
studied the problem by comparing the commonly used medication tramadol against both placebo and non-steroidal anti-inflammatory drugs in client - owned dogs in a
randomized, blinded, placebo and positive - controlled crossover
study.
That intervention has been evaluated in 3
randomized clinical trials by Australian psychologist Sophie Havighurst, and has also been found effective in a
study in South Korea
led by Certified Gottman Therapist Dr. Christina Choi both in 2 orphanages in Seoul and in Busan.
The KEEP - P
study,
led by Phil Fisher, will conduct a
randomized clinical trial of a new, low - cost, manualized, group - based intervention for foster preschoolers and their caregivers.
Owen's parents, Barbara and Jeffery Barthold, signed on to participate in a pilot
randomized controlled trial
led by Lehigh researchers to
study whether a 10 - week training session for parents of young children at - risk for attention deficit hyperactivity disorder (ADHD) would impact children's behavior — and how an online version of the training compared to a face - to - face format.
In 1998, we conducted a
randomized, controlled trial of a simple, behavioral infant sleep intervention (the Infant Sleep
Study) that
led to significant reductions in infant sleep problems and maternal report of depression symptoms 4 months later.10 In 2001, when the children were aged 3 to 4 years, we followed the participants of the earlier trial, all of whom had sleep problems at entry to the Infant Sleep
Study.