These mouse models could shed light on a wide
range of human diseases such as diabetes, many types of cancers, and even neurological diseases such as depression.
About the La Jolla Institute for Allergy and Immunology The La Jolla Institute for Allergy and Immunology is dedicated to understanding the intricacies and power of the immune system to that we may apply that knowledge to promote human health and prevent a wide
range of human diseases.
National Center for Advancing Translational Sciences (NCATS)-- Est. in 2011 The mission of NCATS is to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide
range of human diseases and conditions.
The zebrafish is also being used to identify the genes and pathways underlying a broad
range of human diseases from cardiovascular and musculoskeletal disease to deafness and cancer.
These cells can potentially turn into many different types of cells, and offer staggering potential for treating a huge
range of human diseases.
Not exact matches
The U.S. Centers for
Disease Control and Prevention (CDC) says
human exposure to BPA has dropped significantly in recent years, but some health and environmental groups believe more needs to be done to get BPA out
of consumer products because a wide
range of products — such as food storage containers, plastic tableware, and food packaging — are still manufactured with BPA.
And researchers have developed a wide
range of sophisticated computer models that simulate
human biology and the progression
of developing
diseases.
There are eight
human herpes viruses, and they cause a wide spectrum
of diseases,
ranging from common cold sores to cancer.
Transgenic Huntington's
disease monkeys display a full spectrum
of symptoms resembling the
human disease,
ranging from motor problems and neurodegeneration to emotional dysregulation and immune system changes, scientists at Yerkes National Primate Research Center, Emory University report.
And in the United States, the National
Human Genome Research Institute in Bethesda, Maryland, recently funded three Mendelian Disorders Sequencing Centers that will apply genome sequencing to diagnosing thousands
of patients with a wider
range of rare
diseases, including intellectual disability and developmental delay.
This proof -
of - principle study shows «for the first time... that
human iPS cells can be used to model a diverse
range of inherited
diseases in adult cells,» the authors wrote in their paper, published online in The Journal
of Clinical Investigation August 25.
Poinar suggested in the journal American Entomologist that the origins
of this deadly
disease, which today can infect animals
ranging from
humans and other mammals to birds and reptiles, may have begun in an insect such as the biting midge more than 100 million years ago.
The study has produced more than 20 publications examining a
range of complex
human conditions, including cardiovascular
disease, breast and lung cancer, and type I and II diabetes.
«The imaging technique could shed light on the immune dysfunction that underpins a broad
range of neuroinflammatory
diseases, such as Alzheimer's
disease, depression, post-traumatic stress disorder and addiction,» said Christine Sandiego, PhD, lead author
of the study and a researcher from the department
of psychiatry at the Yale School
of Medicine in New Haven, Conn. «This is the first
human study that accurately measures this immune response in the brain.
Extending that approach to the social sciences more generally could help us develop forecasting tools to assess a whole
range of problems threatening
human society — not just the ravages
of the markets, but wars,
disease and demographic change.
The
human body is a habitat for a huge
range of harmless and beneficial microbes, which may be the key to fighting
disease without antibiotics.
«While further research is needed to conclusively demonstrate a link, the dog may indeed be a sentinel for
humans — it shares the same environment, exhibits the same
range of diseases, many with the same frequency and responds in a similar way to therapies.»
«The project has made important new contributions towards describing the role
of rare genetic variants in a broad
range of disease scenarios and
human traits.»
Human mobility is expected to continue to rise, creating a
range of impacts, such as invasive species, drug resistance spread and
disease pandemics.
«There are a
range of metabolic
diseases and other liver disorders where if you fix a mutated gene you might be really able to have an impact on
human health,» Anderson says.
«Neanderthal DNA influences a broad
range of traits relevant to
disease risk in modern
humans,» Capra told Live Science.
To study the still unknown pathogenesis
of the
disease, the researchers developed a mouse model susceptible to the full
range of infection by the
human parasite.
If it does a similar job in
humans, it could have huge potential for treating a wide -
range of age - related
diseases, say the researchers behind the latest work.
With their new method, Zhang and her colleagues hope to soon begin looking at the unique properties
of human astrocyte cells in a
range of disease types, including Alzheimer's, ALS, stroke, injury, autism, and schizophrenia.
Knowing how cells exert force and sense mechanical feedback in their microenvironment is crucial to understanding how they activate a wide
range of cellular functions, such as cell reproduction, differentiation and adhesion — basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects
of human health and
disease.
Still, many medical researchers insist that the cloning
of human embryos continue because the tissue derived from stem cells might treat
diseases ranging from diabetes to Parkinson's.
In animal tests and in accidental high - level exposures
of humans, the chemicals have caused a
range of damage and
disease, including cancers, sterility, and birth defects.
Ablynx is engaged in the discovery and development
of Nanobodies ® to treat a
range of serious
human diseases.
«We discovered associations between Neandertal DNA and a wide
range of traits in modern
humans, including immunological, dermatological, neurological, psychiatric, and reproductive
diseases,» said senior author John Capra, assistant professor
of biological sciences at Vanderbilt University.
My research combines the use
of mathematical models and statistical methods to understand the transmission dynamics and control
of a
range of infectious
diseases of humans and animals.
The Cancer, Ageing and Somatic Mutation Programme encompasses three Projects that respectively cover the genomics
of human cancers; functional analysis
of the cancer genome using a
range of in vitro and in vivo model systems; and the characterisation
of somatic mutations in development and adult homeostasis in health and
disease.
In infected
humans, the
disease provokes a
range of effects.
In
humans, defects in cilia assembly or function are responsible for a wide
range of diseases called ciliopathies.
Dr. Torkamani's research covers a broad
range of areas centered on the use
of genomic technologies to identify the genetic etiology and underlying mechanisms
of human disease in order to define precision therapies for
diseased individuals.
Researchers have produced knockout mice with characteristics similar to
humans suffering from a wide
range of disorders, including cancer, heart
disease, neurological disorders and even obesity.
NYSCF partners with a broad
range of institutions, foundations, centers and companies in a variety
of ways
ranging from the creation
of fundamental research resources such as iPSC lines for a
disease area to developing
human disease models in vitro to enable drug discovery and toxicity testing.
About the La Jolla Institute for Allergy and Immunology The La Jolla Institute for Allergy and Immunology is dedicated to understanding the intricacies and power
of the immune system so that we may apply that knowledge to promote
human health and prevent a wide
range of diseases.
The meeting is open to a wide
range of INFRAFRONTIER stakeholders including Personalised Medicine initiatives, Rare
Disease networks, funders, regulators and the INFRAFRONTIER user community to discuss advances in CRISPR / Cas9 technology to model
human conditions.
It spreads within the host population efficiently, causing a
range of diseases in
humans, including congenital disorders and cancers.
Cell therapy is a novel technology which bears the potential to treat a wide
range of human degenerative
diseases.
Background:
Human myeloproliferative disorders form a
range of clonal haematological malignant
diseases, the main members
of which are polycythaemia vera, essential thrombocythaemia, and idiopathic myelofibrosis.
I study many traits and
diseases of complex genetic background,
ranging from autism and obsessive compulsive disorders in
humans to cancer and behavioral disorders in dogs.
Using a discovery platform whose components
range from yeast cells to
human stem cells, Whitehead Institute scientists have identified a novel Parkinson's
disease drug target and a compound capable
of repairing neurons derived from Parkinson's patients.
Her work has unraveled the intricacies
of how viruses evade the
human immune system and uncovered molecular targets for the development
of drugs and vaccines for a
range of infectious
diseases.
CAMBRIDGE, Mass. — Using a discovery platform whose components
range from yeast cells to
human stem cells, Whitehead Institute scientists have identified a novel Parkinson's
disease drug target and a compound capable
of repairing neurons derived from Parkinson's patients.
However, current results point to a possible role for hNPCctx in the treatment
of at least some forms
of human retinal degenerative
diseases and highlight the versatility and efficacy
of these cells as therapeutic tools in a broad
range of neurodegenerative disorders [10]--[12], [66].
We will seek investigators that span a
range of metabolism expertise, with an emphasis on interdisciplinary and collaborative - minded researchers passionate about exploring the basic molecular and mechanistic underpinnings
of cellular metabolism and its dysfunction in
human disease.
Importantly, more that 400 different mutations in the lamin A gene have been reported, which are associated with a wide
range of human degenerative
diseases including muscular dystrophy, lipodystrophies and neuropathies.
By supporting Directive 2010 / 63 / EU, LERU wishes to call attention to the fundamental importance
of the use
of animals in research and the vital role it plays in understanding and providing treatment for a
range of debilitating and life threatening
human diseases such as cancer, primary immunodeficiencies, neuro - degenerative
diseases and heart failure.
ABOUT LA JOLLA INSTITUTE La Jolla Institute for Allergy and Immunology is dedicated to understanding the intricacies and power
of the immune system so that we may apply that knowledge to promote
human health and prevent a wide
range of diseases.