Bachelerie F. CXCL12 / CXCR4 - axis dysfunctions: Markers of
the rare immunodeficiency disorder WHIM syndrome.
«CRISPR gene editing takes on
rare immunodeficiency disorder.»
Researchers have harnessed the CRISPR - Cas9 technology to correct mutations in the blood stem cells of patients with
a rare immunodeficiency disorder; the engineered cells successfully engrafted in mice for up to five months.
CSL's core business — CSL Behring — is the separation of blood and blood plasma into its core components to treat
rare immunodeficiency and bleeding diseases.
Not exact matches
Notably, research groups might be able to apply the approach described in this study to develop treatments for other blood diseases such as β - thalassemia, severe combined
immunodeficiency (SCID), chronic granulomatous disease,
rare disorders like Wiskott - Aldrich syndrome and Fanconi anemia, and even HIV infection.
Other primate
immunodeficiency viruses, such as SIV and HIV - 2, the
rarer and less virulent human virus, do not need their host's cyclophilin A to replicate.
Discovery of a novel, advanced technique to identify the
rare cells where human
immunodeficiency virus (HIV) hides in patients taking antiretroviral therapy (ART).
WHIM (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis) syndrome is a
rare congenital hematological
immunodeficiency disorder in which mature neutrophils fail to reach blood circulation from bone marrow.
A form of severe combined
immunodeficiency (SCID), a genetically and clinically heterogeneous group of
rare congenital disorders characterized by impairment of both humoral and cell - mediated immunity, leukopenia, and low or absent antibody levels.
Immunodeficiency, Centromere region instability, Facial anomalies syndrome (ICF) is a
rare autosomal recessive disease that damages the immune system.
Primary
Immunodeficiencies (PIDs) are a group of
rare genetic diseases characterized by an altered innate and adaptive immune system, leading to increased susceptibility to infections, risk of autoimmunity and cancer.
Her main area of research is in CVID (common variable
immunodeficiency) and antibody deficiency which resulted in better understanding of this
rare group of disorders.
Primary
immunodeficiencies are
rare but can be extremely serious, and a PID diagnosis is life - changing for both the young child affected and their families.
For example, in the
rare disease of Severe Combined
Immunodeficiency a dam will be perfectly healthy but will pass on to fifty percent of her puppies the X gene with the recessive gene for the disease.
When researchers identified the human
immunodeficiency virus as the reason why young, previously healthy people were developing
rare cancers and wasting away, it was a triumph of medical science.