Sentences with phrase «rare nonsynonymous»

Helgason H A rare nonsynonymous sequence variant in C3 is associated with high risk of age - related macular degeneration

Not exact matches

Yet each one tells a different story: (a), how novel - to - dbSNP variants were rare; (b), how nonsynonymous variant frequencies are shifted to lower values relative to those of synonymous variants, (c), how this shift in allele frequencies is more pronounced for damaging nsSNPs, consistent with natural selection, and (d), how the sizes of observed indels are enriched for non-frameshift events divisible by 3.