There are many good reasons for this, but with low - cost whole genome sequencing I think that we can explore the whole genomes of
rare tumor types as well.
With TCGA, ICGC, and other datasets as a framework for comparison, we can undoubtedly learn a great deal about the somatic changes underlying
rare tumor types.
In recent years, my laboratory has discovered driver mutations, which confer a selective growth advantage and thus promote cancer development, for certain
rare tumor types.
Not exact matches
With the approval of the local ethics committee, a 16 - year - old boy with a
rare type of liver cancer called fibrolamellar hepatocellular carcinoma was given infusions of 3BP into the blood vessels supplying the
tumor, formulated in a proprietary and patented fashion.
Unlike other solid
tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this
rare cancer
type have not been available for research.
«First drug target identified for children with
rare type of brain
tumor.»
Dr. Le, who holds the Thomas L. Shields, M.D. Professorship in Dermatology, said he and his researchers serendipitously uncovered this explanation for balding and hair graying while studying a disorder called Neurofibromatosis
Type 1, a
rare genetic disease that causes
tumors to grow on nerves.
Results of a phase one trial show that an investigational topical drug, resiquimod gel, causes regression of both treated and untreated
tumor lesions and may completely remove cancerous cells from both sites in patients with early stage cutaneous T cell lymphoma (CTCL)-- a
rare type of non-Hodgkin lymphoma that affects the skin.
Occurrence of this
type of
tumor on the tongue is exceedingly
rare, says author Dr Manisha Biradar.
The Endocrine Society issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of two
types of
rare adrenal
tumors — pheochromocytomas and paragangliomas — that can raise the risk of cardiovascular disease and even death if left untreated.
This week, researchers at the National Cancer Institute (NCI) unveiled a project on their wish list: a much broader survey of 10,000
tumors per cancer
type that would aim to pin down very
rare cancer genes.
Tumor profiling can also reveal
rare mutations and other changes that make some cancers unusually responsive to targeted drugs — knowledge that can be applied to patients with a variety of cancer
types.
While most
types of primary brain cancer may spread within the brain, it is
rare for a primary brain
tumor to spread outside the brain.
MassGenomics writes about researchers in Canada who decided to try to help an 80 - year - old patient with a
rare type of
tumor -LSB-...]
Tumors are notoriously heterogeneous — the product of genetic mutations that may be common in a particular
type of cancer, or exceedingly
rare.
«We found a strong reduction in the risk of estrogen - receptor - negative [ER --RSB- breast cancer in particular, which is exciting because that
type of
tumor, while
rarer than estrogen - receptor - positive [ER +]
tumors, tends to be aggressive.»
The list included multiple
types of benign
tumors, a fatty
tumor called a lipoma, and
rare metastatic
tumors.
Adrenal
tumors of all
types are
rare in cats.
Adrenal medullary
tumors are
rare but pheochromocytomas are the most common
type and usually occur in middle aged to older dogs.
«Titan's
tumor ended up being a very
rare type of benign kidney
tumor,» happily reported Dr. Doyle.
In
rare cases a
tumor called fibrosarcoma may develop at the injection site, however, this has been found to develop in only specific individuals who are genetically predisposed to form these
tumors secondary to any
type of infection or inflammation.
Among canine benign bone
tumors, an Osteoma is a
rare type of
tumor.