Sentences with phrase «ras lung tumor»

Not exact matches

One of those genes, K - Ras, which was discovered nearly 30 years ago, is mutated in 30 percent of human tumors, including 90 percent of pancreatic cancers, 40 percent of colon cancers, and 20 percent of non-small cell lung cancers.

This demonstrated that non-small-cell lung cancer selectively requires autophagy for tumor development and that therapeutically targeting autophagy may be an alternative to targeting Ras.

Mutations in one of these genes, NF1 — a known tumor suppressor gene that regulates the RTK / RAS / RAF pathway — had previously been reported in lung cancer.

22) Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly - Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, DePinho RA, Kemp CJ, Varmus HE, Hanash SM (2011) Lung cancer signatures in plasma based on proteome profiling of mouse tumor models.