I learn through an aggregate experience of getting my face slammed into the ground over and over again until I'm conditioned to stop responding to stimuli inappropriately and start doing whatever gets
my rat brain rewarded.
High - calorie and exceedingly pleasurable foods appear to change
rat brain rewards circuitry, causing the rodents to continue to seek such fare.
Not exact matches
They used electrodes to measure the sensitivity of
rats»
brains to
reward activity.
The researchers think that, you know, the sweetness is producing a
reward effect in the
brain that's actually stronger than cocaine's
reward effect; same kind of dopamine mechanism and the researchers just think this is something biological that the
rats are saying, «Hey this is sweet, must be food, must be good for me.»
Biochemical tests of the adult animals showed that THC - doused
brains had the same number of receptors that responded to THC as unexposed
rat brains, but more receptors for heroin and more of a compound associated with
reward behavior in their neurons, the team reports online 5 July in Neuropsychopharmacology.
Not only do
rats return over and over again to the place they were tickled, the handling triggers the neurotransmitter dopamine in key
reward - related
brain circuits in the rodents, he says.
Interestingly, these
rats were still motivated to drink sugar water, indicating that the researchers had successfully targeted only alcohol - activated neurons, not the
brain's overall
reward system.
In
rat models of non-dependent drinking, switching off the alcohol - linked neurons had little effect on future drinking — the
brain just seemed to switch on a new group of neurons, as if the
brain's path from alcohol to
reward was not established yet.
However, when the «alcohol
rats» were treated with OSU6162 it was found that the substance counteracted the low concentrations of dopamine in the
brain reward system.
A study of
rats published at the same time in the scientific journal Addiction Biology adds to the understanding of how OSU6162 works, as it shows that
rats that voluntarily consumed alcohol for almost a year had lower levels of dopamine in their
brain reward system than
rats that had never drunk alcohol.
The researchers think that a junk diet causes lasting changes in the
reward circuit parts of the
rats»
brain, for example, the orbitofrontal cortex, an area of the
brain responsible for decision - making.
Now researchers reporting in the Cell Press journal Neuron on July 18 show in a study conducted in
rats that even a single exposure to nicotine temporarily changes how the
brain's
reward system responds to alcohol and increases the reinforcing properties of alcohol via stress hormones.
A third electrode, running to the
brain's pleasure center, incited the
rats to move forward and
rewarded them for making the proper turn.
Using a technique that employs light to control nerve cell activity, researchers in Professor Jeff Wickens» Unit inactivated a region of the
brain and showed that it caused the
rats to behave more flexibly while trying to get a
reward.
Rewards sent directly to the brain can be more effective than food rewards, Burwell said, because rats can be rewarded in the moment of desired performance, and they don't become sa
Rewards sent directly to the
brain can be more effective than food
rewards, Burwell said, because rats can be rewarded in the moment of desired performance, and they don't become sa
rewards, Burwell said, because
rats can be
rewarded in the moment of desired performance, and they don't become satiated.
McGehee and his colleague, post-doctoral researcher Huibert Mansvelder, PhD, working with
brain tissue from
rats, demonstrated how nicotine takes control of the
reward pathways.
Spangler R, Wittkowski KM, Goddard NL, et al: Opiate - like effects of sugar on gene expression in
reward areas of the
rat brain.