In order to test whether the particles could change the behavior of cells, the team injected a sample onto
cultured rat dorsal root ganglia neurons, which are found in the peripheral nervous
system.
Enriched by the rapid evolution of these technologies, TEFOR - TACGene has developed a solid expertise in the design, production and use of TALE - N and CRISPR / Cas9
systems, both for its own research projects in
cultured cells and in collaboration, in many model organisms, including the
rat, zebrafish, Drosophila, and Xenopus as part of the National Infrastructure in Biology and Health TEFOR supported by Investissement d'Avenir programme (2012 - 2019).
The
culture system supports normal differentiation of the Sprague — Dawley
rat testes for 3 days (Habert et al., 1991) and has been validated for toxicological studies (Lassurguere et al., 2003; Chauvigne et al., 2009).