Sentences with phrase «rat glioma»
Global gene expression analyses reveal changes in biological processes after hyperthermia in a rat glioma model.
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Now, Johns Hopkins researchers report they have used nanoparticles to successfully deliver a new therapy to glioma cells in the brains of rats, prolonging their lives.
«We then evaluated the system in rats with glioma and found that by using a method called intracranial convection - enhanced delivery, our nanoparticles could penetrate completely throughout the tumor following a single injection,» says Jordan Green, Ph.D, associate professor of biomedical engineering and ophthalmology at Johns Hopkins.
Historically, the typical incidence of gliomas and schwannomas in normal rats has been about 2 per cent and 1 per cent, respectively.
They found that the exposed rats were more likely to develop cancers, specifically malignant gliomas — a tumor of glial cells in the brain — and tumors in the heart.