It also should be noted that the economy seems to be particularly sensitive to interest -
rate changes in this cycle, so there is a risk for unintended economic damage if the Fed moves too fast or too far.
Not exact matches
In contrast, the U.S. Federal Reserve is in the middle of a rate - hiking cycle although no changes to monetary policy are expected when the bank concludes a two - day meeting on Wednesda
In contrast, the U.S. Federal Reserve is
in the middle of a rate - hiking cycle although no changes to monetary policy are expected when the bank concludes a two - day meeting on Wednesda
in the middle of a
rate - hiking
cycle although no
changes to monetary policy are expected when the bank concludes a two - day meeting on Wednesday.
Chart 2 shows the historical positive correlation between
changes in the Fed Funds
rate and the profits
cycle.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth
in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures
in European countries that may increase the amount of discount required on Gilead's products; an increase
in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift
in payer mix to more highly discounted payer segments and geographic regions and decreases
in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations
in ADAP purchases driven by federal and state grant
cycles which may not mirror patient demand and may cause fluctuations
in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials
in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations
in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates
in the timelines currently anticipated; Gilead's ability to receive regulatory approvals
in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta
in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations
in the foreign exchange
rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time
in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
These risks include,
in no particular order, the following: the trends toward more high - definition, on - demand and anytime, anywhere video will not continue to develop at its current pace or will expire; the possibility that our products will not generate sales that are commensurate with our expectations or that our cost of revenue or operating expenses may exceed our expectations; the mix of products and services sold
in various geographies and the effect it has on gross margins; delays or decreases
in capital spending
in the cable, satellite, telco, broadcast and media industries; customer concentration and consolidation; the impact of general economic conditions on our sales and operations; our ability to develop new and enhanced products
in a timely manner and market acceptance of our new or existing products; losses of one or more key customers; risks associated with our international operations; exchange
rate fluctuations of the currencies
in which we conduct business; risks associated with our CableOS ™ and VOS ™ product solutions; dependence on market acceptance of various types of broadband services, on the adoption of new broadband technologies and on broadband industry trends; inventory management; the lack of timely availability of parts or raw materials necessary to produce our products; the impact of increases
in the prices of raw materials and oil; the effect of competition, on both revenue and gross margins; difficulties associated with rapid technological
changes in our markets; risks associated with unpredictable sales
cycles; our dependence on contract manufacturers and sole or limited source suppliers; and the effect on our business of natural disasters.
The official poverty statistics show a sharp decline
in the poverty
rate between 1959 and 1969 but little real
change since then, apart from fluctuations due to the business
cycle.
Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to
rate the Notes at the anticipated
ratings levels, which is a closing condition, or at all;
changes in the financial markets, including
changes in credit markets, interest
rates, securitization markets generally and our proposed securitization
in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit
ratings, if any, are issued with respect to the Notes; the extended settlement
cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described
in our Annual Report on Form 10 - K for the year ended December 31, 2017 and
in other documents that we file with the Securities and Exchange Commission from time to time which are or will be available on the Commission's website at www.sec.gov.
In talking about monetary policy's contribution to the management of the economic challenges, the speech notes the recent increases in mortgage rates of the commercial banks, outside of the cycle of changes in the cash rat
In talking about monetary policy's contribution to the management of the economic challenges, the speech notes the recent increases
in mortgage rates of the commercial banks, outside of the cycle of changes in the cash rat
in mortgage
rates of the commercial banks, outside of the
cycle of
changes in the cash rat
in the cash
rate.
Additionally, the U.S. economy has dramatically
changed over the past several years, with structural factors (largely the result of technological innovation and shifting demographic trends) influencing it
in a manner that makes comparisons to past
rate hiking
cycles less relevant.
As seen
in prior
cycles,
changes in short - term interest
rates alone had yielded little effect on financial conditions, as buoyant risk sentiment strengthened equities, corporate bonds, as well as various forms of «esoteric» investments.
As households have simultaneously increased their debt levels and equity holdings, they are now much more exposed to
changes in interest
rates and equity prices than has been the case
in previous
cycles.
And that's before accounting for some of the factors that the model doesn't consider: the disagreement
in the polls, the unusual nature of Trump's candidacy and the demographic
changes it is producing, Clinton's superior turnout operation, the possibility of «shy Trump» voters, the fact that the news
cycle is still somewhat fluid headed into the final weekend, the declining response
rates to polls, and the substantial number of high - profile polling misses around the world over the past few years.
Earth System Threshold Measure Boundary Current Level Preindustrial Climate
Change CO2 Concentration 350 ppm 387 ppm 280 ppm Biodiversity Loss Extinction
Rate 10 pm > 100 pm * 0.1 - one pm Nitrogen
Cycle N2 Tonnage 35 mmt ** 121 mmt 0 Phosphorous
Cycle Level
in Ocean 11 mmt 8.5 - 9.5 mmt — 1 mmt Ozone Layer O3 Concentration 276 DU # 283 DU 290 DU Ocean Acidification Aragonite ^ ^ Levels 2.75 2.90 3.44 Freshwater Usage Consumption 4,000 km3 ^ 2,600 km3 415 km3 Land Use
Change Cropland Conversion 15 km3 11.7 km3 Low Aerosols Soot Concentration TBD TBD TBD Chemical Pollution TBD TBD TBD TBD * pm = per million ** mmt = millions of metric tons #DU = dobson unit ^ km3 = cubic kilometers ^ ^ Aragonite is a form of calcium carbonate.
Finney believes that
changes in climate cause the
cycles in salmon populations, and as scientists struggle to understand the
rate and effects of global warming, salmon may help them distinguish normal climate variations from the early warnings of a system gone dangerously wrong.
Given the current dramatic
rate of
change in the ocean nitrogen
cycle the researchers are not sure how long it will take for marine ecosystems to adapt.
Scientists have long known that small
changes in Earth's water
cycle could lead to large, although temporary,
changes in the
rate of sea level rise.
In a paper published in Science Advances, he proposes that mass extinction occurs if one of two thresholds are crossed: For changes in the carbon cycle that occur over long timescales, extinctions will follow if those changes occur at rates faster than global ecosystems can adap
In a paper published
in Science Advances, he proposes that mass extinction occurs if one of two thresholds are crossed: For changes in the carbon cycle that occur over long timescales, extinctions will follow if those changes occur at rates faster than global ecosystems can adap
in Science Advances, he proposes that mass extinction occurs if one of two thresholds are crossed: For
changes in the carbon cycle that occur over long timescales, extinctions will follow if those changes occur at rates faster than global ecosystems can adap
in the carbon
cycle that occur over long timescales, extinctions will follow if those
changes occur at
rates faster than global ecosystems can adapt.
«we estimate that less than 23 %, at the 95 % confidence level, of the 11 - year
cycle changes in the globally averaged cloud cover observed
in solar
cycle 22 is due to the
change in the
rate of ionization from the solar modulation of cosmic rays.»
It has been argued that the land amplification is associated with lapse
rate changes (not represented
in the UVic model), and it is certain that drying of the land can play a role (not reliable
in the UVic model since diffusing water vapor gives you a crummy hydrological
cycle, especially over land).
Thus, with higher growth
rates and faster technological and structural
change, people with vocational training may be more likely to be out of the labor market later
in the life
cycle.
Year 4 Science Assessments Objectives covered: Recognise that living things can be grouped
in a variety of ways Explore and use classification keys to help group, identify and name a variety of living things
in their local and wider environment Recognise that environments can
change and that this can sometimes pose dangers to living things Describe the simple functions of the basic parts of the digestive system
in humans Identify the different types of teeth
in humans and their simple functions Construct and interpret a variety of food chains, identifying producers, predators and prey Compare and group materials together, according to whether they are solids, liquids or gases Observe that some materials
change state when they are heated or cooled, and measure or research the temperature at which this happens
in degrees Celsius (°C) Identify the part played by evaporation and condensation
in the water
cycle and associate the
rate of evaporation with temperature Identify how sounds are made, associating some of them with something vibrating Recognise that vibrations from sounds travel through a medium to the ear Find patterns between the pitch of a sound and features of the object that produced it Find patterns between the volume of a sound and the strength of the vibrations that produced it Recognise that sounds get fainter as the distance from the sound source increases Identify common appliances that run on electricity Construct a simple series electrical circuit, identifying and naming its basic parts, including cells, wires, bulbs, switches and buzzers Identify whether or not a lamp will light
in a simple series circuit, based on whether or not the lamp is part of a complete loop with a battery Recognise that a switch opens and closes a circuit and associate this with whether or not a lamp lights
in a simple series circuit Recognise some common conductors and insulators, and associate metals with being good conductors
Directly, that translates to 372 miles, though VW notes
in the U.S. driving
cycle it's likely to be
rated at 270 miles unless driving range calculations suddenly
change between now and when a production version of the BUZZ goes on sale.
The 2016 Chevrolet Malibu Hybrid (earlier post) is EPA -
rated at 46 mpg (5.11 l / 100 km) combined, 47 mpg city and 46 mpg highway; the powertrain shares the transmission architecture with the 2016 Chevrolet Volt extended range electric vehicle (EREV), but includes
changes to optimize the system for engine - driven charge - sustaining operation
in the range of conditions represented by the US EPA 5
cycle fuel economy tests.
Any variable
rate adjustment based on a change in the Prime Rate and your corresponding index or margin will be effective as of the first day of the current billing cycle, and will apply to all new and outstanding Account balances and transactions subject to that variable r
rate adjustment based on a
change in the Prime
Rate and your corresponding index or margin will be effective as of the first day of the current billing cycle, and will apply to all new and outstanding Account balances and transactions subject to that variable r
Rate and your corresponding index or margin will be effective as of the first day of the current billing
cycle, and will apply to all new and outstanding Account balances and transactions subject to that variable
raterate.
The Prime
Rate Index used to determine your APR is the rate published in The Wall Street Journal quarterly (January, April, July and October) and changes are effective as of the first date of your next billing cy
Rate Index used to determine your APR is the
rate published in The Wall Street Journal quarterly (January, April, July and October) and changes are effective as of the first date of your next billing cy
rate published
in The Wall Street Journal quarterly (January, April, July and October) and
changes are effective as of the first date of your next billing
cycle.
The interest
rate cycle is about to
change and the flow of funds is slowly
changing in capital markets.
Interest
rates are also posted on Account detail pages; for these pages, any
changes to interest
rates are updated
in the nightly processing
cycle on the effective date of the
change.
For this
cycle, and for the moment, more important than any small
change in the overnight
rate is that the Federal Reserve has begun to step away from actively and directly supporting the mortgage market though purchases Mortgage - Backed Securities (MBS) and Treasuries.
A
change in the prime
rate will take effect on the first day of the first billing
cycle after the
change.
Generally speaking the longer the term of a bond the greater the sensitivity that bond will have to the movement
in interest
rates,
changes in the credit quality of a company or company risks associated with the business
cycle of a specific company, sector or economy.
Fluctuations
in the business
cycle are essentially distinct
changes in the
rate of growth
in economic activity.
If the Prime
Rate changes, the new APRs will take effect on the first day of your billing
cycle beginning
in the next month.
Since carbon
cycle models allow us to understand past
changes in atmospheric CO2 and 13C concentrations it is also possible to use these models to infer the 14C production
rate based on measured 14C concentrations
in tree rings.
If there is a 60 year signal here, it would seem like you would want to measure
change in rates as peak to peak from 1940 to 2000 versus a (1960 to 1980) vs (1980 to 2000) which would not be representative due to the multi-decadal
cycle.
The issue with the Mauritsen and Stevens piece is that it tries to go well beyond a «what if» modeling experiment, and attempts to make contact with a lot of other issues related to historical climate
change (the hiatus,
changes in the hydrologic
cycle, observed tropical lapse
rate «hotspot» stuff,
changes in the atmsopheric circulation, etc) by means of what the «iris» should look like
in other climate signals.
I still see the Milankovitch
cycles as incredibly gentle and the
rate of our
changes as massive
in comparison.
Examples of less certain science include understanding the effects of climate
change on extreme weather
in different regions, the role the deep ocean plays
in the climate
cycle and the
rate at which sea level will rise over the next century.
Now we have a correlation between economic
cycles and
rates of
change in Length of Day Lunar
cycles (sunspots involved too!
2)
In the link of Bob Tisdale, http://i33.tinypic.com/2uotpjb.jpg, there can be seen that ENSO cycles have an effect, too, on the changes of rising rate of CO2 content in atmospher
In the link of Bob Tisdale, http://i33.tinypic.com/2uotpjb.jpg, there can be seen that ENSO
cycles have an effect, too, on the
changes of rising
rate of CO2 content
in atmospher
in atmosphere.
Here is the
rate of
change in sea ice extent filtered with 182 day gaussian to remove the annual
cycle.
That is the crux of the matter: the 150 GtC
in and out is not the net sink
rate it is the source
rate and the sink
rate of a
cycle, which doesn't
change the CO2 content of the atmosphere.
No significant imbalance occurs despite large
changes in the
rate of energy release by the oceans and significant
changes in the speed of the hydrological
cycle via
changes in the air circulation systems.
My idea is to take a simple sinusoidal model of a beat wave composed of 9 and 20 year
cycles (the two main frequencies
in the instrumental record of global temperature) and subject them to disturbances with a random variable having a standard deviation comparable to the standard deviation of monthly
changes in the
rate of
change in global temperature.
As I said
in my comments on Roy's blog, I think the
rate of
change in temperature is composed of a «persistent» force from natural
cycles of decadal and bidecadal (and possibly longer) length, and an «anti-persistent» tendency from random shocks to the system.
This shows up strongly
in the
rate of
change cycle that is clearly evident
in the records.
Modelling studies from both Pierce & Adams (2009) and Kazil et al. (2012) concluded that global cloud condensation nuclei (CCN) would not be sensitive to
changes in the ion - induced nucleation
rate over a solar
cycle.
I did suggest some time ago to Dr Bob Tisdale across at WUWT that perhaps a difference
in the
rate of energy loss during both the warming and cooling phases of ENSO and PDO
cycles, because of a
change in the atmospheric albedo, could provide a physical explanation for the correlation they were describing, but the hypothesis was not favoured.
Randle says climate
change — which may already be increasing the intensity of droughts and,
in turn, wildfires — is driving a vicious
cycle whereby sedimentation
rates increase.
(a) Scientific, socio - economic, technical, and methodological issues, including the role of forests,
in particular tropical forests,
in the global carbon
cycle; definitional issues, including those relating to links between deforestation and degradation; data availability and quality; scale;
rates and drivers of deforestation; estimation of
changes in carbon stocks and forest cover; and related uncertainties;
Gerard Roe (U. Washington) showed that the
rate of
change of global ice volume correlates beautifully with the
changes in incoming solar radiation due to Milankovitch
cycles (Roe, 2006).