Rational design approaches to this problem have often used complex computational methods, have targeted simple model reactions and have typically led to low levels of catalysis1.
«We think we can use our molecular,
rational design approaches to make a better flu vaccine for people who really need it,» says study leader Andrew Pekosz, PhD, an associate professor in the Department of Molecular Microbiology and Immunology at the Bloomberg School of Public Health.
Not exact matches
«We gained this valuable knowledge through multidisciplinary basic research and
approaching the problem with a
rational design.»
Dr. Schwartz thinks that treatment of uveal melanoma will ultimately involve
rational drug
design and a combination of drugs, similar to the
approach used to combat HIV infection.
Rational and modern
design approaches to this problem have been developed, using complex computational methods but without conclusive results.
«This cell - targeted EPO
approach demonstrates a new theoretical basis for the
rational design of engineered protein fusion drugs.»
The structural information is used for the
rational design and development of small molecular inhibitors in combination with chemical biology
approaches.
His work centers on developing general,
rational approaches to
design precision medicines from genome sequences by targeting the RNA product of genes.
The yeast platform is one step toward the next stage Kruse envisions for GPCRs: A
rational approach to finding and
designing drugs to trigger or block specific activity.
The
approach is to use clinically relevant tumor models such as patient - derived xenografts (PDXs), as well as humanized and immunocompetent transgenic tumor - bearing mice to
design rational combinations of novel and emerging cancer therapies, including tumor - targeting and immune - stimulating therapies, to ultimately improve treatment outcomes for cancer patients.
AVAILABLE SUMMER 2016 The Eureka Math Curriculum Study Guide, Grade 7 provides an overview of all of the Grade 7 modules, including Ratios and Proportional Relationships
Rational Numbers Expressions and Equations Percent and Proportional Relationships Statistics and Probability Geometry FEATURES an overview of what students should be learning throughout the year Information on alignment to the instructional shifts and the standards
design of curricular components
approaches to differentiated instruction descriptions of mathematical models
In this case, Lederer J. found that the Province's
approach lacked a
rational connection to its goals, because the process it implemented was arbitrary and unilateral, and was not carefully
designed.
According to Voss «[h] uman beings are incapable of being
rational... [s] o instead of pretending emotions don't exist in negotiations, hostage negotiators have actually
designed an
approach that takes emotions fully into account and uses them to influence situations -LSB-.]»