Sentences with phrase «rational drug design»

«Overall,» Dr. Schwartz added, «the study underscores the importance of rational drug design, in which drugs are designed to interact with specific molecular pathways involved in a particular disease.

But these results may turn out to be essential for rational drug design and treatment regimens that lead to effective resolution of inflammation in ALI,» Jan Tuckermann resumes.

Dr. Schwartz thinks that treatment of uveal melanoma will ultimately involve rational drug design and a combination of drugs, similar to the approach used to combat HIV infection.

«It is a lot of intelligent planning and hard work, but we have to get lucky too,» says Raman, «because the risk of it not working — using rational drug design — is reasonably high.»

Until now, agents that inhibit Pin1 have been developed mainly through rational drug design.

Rational drug design develops fewer compounds compared to high - throughput screening.

He moved to the National Cancer Institute in 1992 for a post-doctoral fellowship and became interested in rational drug design, a relatively new concept at the time, but one that fit Buolamwini's needs.

The company founder is back, along with the ProMIS rational drug design program.

The finding will trigger a new wave of rational drug design, predicts Robert Weinberg, a cancer biologist at the Massachusetts Institute of Technology.

The bottom line is that although the two forms of the enzyme seem very similar, their active sites are subtly different, and this could be a basis for rational drug design.»

Elion and Hitchings developed a method known as «rational drug design» that helped revolutionize drug making.

rational drug design: which involves designing and synthesising compounds based on the known structure of a specific target molecule.