Prof. Ruiling Zhang and team from Xinxiang Medical University explored the correlation between cyclin - dependent kinase 5 expression in the hippocampus and neurological impairments following prenatal ethanol exposure, and found that prenatal ethanol exposure could
affect cyclin - dependent kinase 5 and its activator p35 in the hippocampus of
offspring rats.
But because the vinclozolin - induced fertility changes occurred in almost every male
rat descended from a treated mother rather than in a small percentage of
offspring (as is seen in germ line mutations caused by radiation), Skinner suspects an epigenetic mechanism — a change that doesn't mutate the DNA sequence of an animal, but rather
affects how genes are expressed.