While the results are promising, particularly in halting a form of MS that progresses rapidly, the team says there is still a long way to go before the treatment
reaches human clinical trials.
They estimate that it will take another eight to ten years before
it reaches human clinical trials.
Not exact matches
Most are already being tinkered with in animal models, and at least four have
reached clinical trials in
humans.
«The ultimate goal of this research will be to advance HIF - 1alpha stabilizers toward
clinical trials in
humans, using versions of the drug that can be taken orally and
reach the urinary tract,» Nizet said.
Looking ahead, this newly generated mouse model offers far -
reaching scope to study the molecular bases of hydrocephalus, a fairly common
clinical condition in
humans, where the causes are often unknown.
Dr. Donnai's efforts in
human genetics education have
reached large and diverse audiences, including
clinical geneticists, genetic counselors, students, and the public.
An increasing number of animal and
human welfare organizations are
reaching that same conclusion, says Jenny Coffey, a licensed
clinical social worker who works for Animal Haven, a shelter in New York City.