The blood - brain barrier protects the brain from poisons but also prevents drugs from
reaching brain tumors.
That barrier protects the brain from toxins in the blood but also keeps drugs in the bloodstream from
reaching brain tumors.
Not exact matches
Published in the February 27 issue of Cell, the study found that
tumor cells that
reach the
brain — and successfully grow into new
tumors — hug capillaries and express specific proteins that overcome the
brain's natural defense against metastatic invasion.
An advantage of small - molecule PPF — which has been previously used in clinical trials in an attempt to treat Alzheimer's disease and dementia — is that it can penetrate the blood -
brain barrier and
reach the
tumor.
Now he and his team are putting cells from human
brain tumors into the organoids, which have
reached the level of development and complexity of a 20 - week - old human fetus's, to see whether they reprise what happens in patients.
Children progressively lose muscle control as the
tumor rapidly attacks the pons, a region deep inside the
brain that connects the
brain to the spinal cord, and is difficult to
reach and surgically remove.
We've also found that when these drugs are used in combinations, they don't
reach high enough concentrations within the
brain tumor to be effective.
«They can cross different fiber tracts in the
brain to
reach tumor cells that have migrated away from the main
tumor mass.
Proton therapy is an advanced form of radiation treatment that is especially effective for
reaching tumors or remaining cancer cells close to key organs such as the
brain stem or spinal cord.
Central nervous system (CNS)
tumors pose a particular challenge for antibody therapeutics, because the blood -
brain barrier (BBB) prevents intravenously - injected antibodies from
reaching CNS metastases.
Brain tumors can be removed surgically if they are located in a site that can be
reached safely.
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