After deciphering the crystal structure of the catalytic domain of PHA synthase, in addition to other structural studies on whole enzyme and
related proteins, the research team also performed experiments to elucidate the
mechanisms of the enzyme
reaction, validating detailed structures, enzyme engineering, and also N - terminal domain studies among others.
Veterinary research has not yet been able to establish the
mechanisms responsible for the possible adverse
reactions related to the various immune
related diseases which may be present upon vaccination.