Not exact matches
Unchecked, these
free radicals cause a chain
reaction of injury to the cells and tissues and, on the skin, results in sun
damage, pigmentation and premature ageing.
Aging - associated increases in oxidative
damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability
of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity
of the
reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels
of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased
free radical production coupled with disruption
of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aging.
The process
of oxidation releases
free radicals, which can trigger chain
reactions leading to the death or
damage of cells.
However, a small minority
of oxidized cells become problematic «
free radicals» that set off a chain
reaction of damage, causing cells to mutate and behave abnormally.
One
of these substances is
free radicals, which in turn produce a type
of chain
reaction causing cell
damage.
The unsaturated lipid molecules
of cell membranes are particularly susceptible to this
damaging free radicals process and readily contribute to the uncontrolled chain
reaction.
Oxidative
damage, another name for the chemical
reaction that
free radicals cause, can lead to a breakdown or even hardening
of lipids, which makeup all cell walls.
Surplus glucose relentlessly reacts with your body's proteins, causing
damaging glycation
reactions while fueling the fires
of chronic inflammation and inciting the production
of destructive
free radicals (Basta 2004; Uribarri 2005; Toma 2009).
Found in many foods, antioxidants break and reduce the chain
reaction of cell
damage caused by
free radicals.