Sentences with phrase «reactivate genes»

But it turns out that a process called somatic cell nuclear transfer (SCNT) can sometimes reactivate genes.

«The point of our study is to show that it's never too late to reactivate the gene,» Bird says.

Mice with the reactivated gene all showed better tissue healing when parts of their ears and paws were injured.

The team produced the first evidence that removing methylation, which are molecular tags that keep a mutant gene shut off, can reactivate the gene and restore the fragile X syndrome neurons.

Not exact matches

Davies and Lineweaver suggest that genes active in embryogenesis and switched off later may be reactivated because of damage, causing the accelerated cell division of these rogue cancer cells.

In leukemia cells it is often the case that genes are reactivated that, in physiological terms, mediate the self - renewal of blood stem cells.

After four weeks of such training, researchers reactivated the p25 gene in the mice for six weeks and then tested them to see if they recalled their shocking experiences.

«We think that these genes, which are normally only expressed in the placenta to facilitate invasion, are becoming reactivated in cancer cells and supporting invasion in this context too,» she says.

First, the genes used for reprogramming are themselves known to trigger cancer, so if they were to reactivate could cause tumours to form.

He is interested in reactivating dormant genes or changing the regulation of active genes in embryos to bring back ancestral traits that have been lost in evolution.

If the genes in the chick embryo are very close to those of an ancestral, nonavian dinosaur — and if the changes, over more than 150 million years, have been almost all in regulation of the genes — then we could reactivate the old pattern of regulation.

They found 204 that reactivated cell proliferation, including two that affected nearly 2000 genes.

They discovered that crucial immune genes are suppressed while the larva lives within the ladybug, but then reactivate after the larva emerges.

However, cancer cells may instead be coaxed to turn back into normal tissue simply by reactivating a single gene, according to a study published June 18th in the journal Cell.

However, cancer cells may instead be coaxed to turn back into normal tissue simply by reactivating a single gene, according to a study that found that restoring normal levels of a human colorectal cancer gene in mice stopped tumor growth and re-established normal intestinal function within only 4 days.

A study published by Cell Press November 7th in the journal Cell has revealed that an evolutionarily conserved gene called Lin28a, which is very active in embryos but not in adults, enhances tissue repair after injury when reactivated in adult mice.

They do this by reactivating dormant genes associated with pluripotency — a primitive state in which a cell has the potential to become any cell type in the body.

Species often dump genes that they no longer use, he notes, but these genes must have stuck around for Crotoniidae to reactivate them.

The work led researchers to stumble upon another potential role for this gene, which enhances the healing power of mice when reactivated.

«Now, with the help of gene therapy and stem cells we can help reactivate the body's response to hypoxia and save limbs.»

BK: As you stated, all of these genes are present in the human genome, but they are regulated differently, so finding mechanisms or therapies that can reactivate them is critical.

When Simon's team deleted all H3.3 genes, they found that certain previously silenced transposable elements were reactivated and continued to multiply in the genome — the result is the appearance of new genetic alleles and chromosomal abnormalities, both are familiar early events in the formation of tumors.

McGarvey, K. M.; Fahrner, J. A.; Greene, E.; Martens, J.; Jenuwein, T.; Baylin, S. B. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.

Preventing Cancer Sulforaphane - filled broccoli sprouts, in oral and topical form, are shown by Kimmel Cancer Center investigators to reactivate a cancer - preventing gene pathway in breast, lung, stomach, and skin cancers.

The newly formed hybrid cells reactivate neuronal precursor genes, and can thereby proliferate.

They discovered that increasing the random activity, or noise, associated with HIV gene expression — without increasing the average level of gene expression — can reactivate latent HIV.

Walnuts and pecans contain ellagic tannins, which the gut transforms into ellagic acid, which converts a cancer cell back into fat - burning, which reactivates the P53 gene, which causes the cell to commit apoptosis.

Many phytochemicals can reactivate tumor suppressor genes silenced by epigenetic modifications.