Sentences with phrase «reactivated lin28a»

They remain dormant in our bodies but can be reactivated in later life by physical and emotional stress, resulting in a condition called shingles.

Furthermore, the hedgehog pathway, a reactivated embryonic pathway in cancer cells, was reported as pyrvinium - sensitive signal transduction mechanism [65].

Freshly isolated tumor - infiltrating T cells are usually inactive against autologous cancer cells but can be reactivated in - vitro by the addition of IL - 2 191.

The latter are longed lived and can be reactivated upon re-infection with the same microbe, initiating a more rapide and effective recall response.

In cancerous cells, telomerase somehow becomes reactivated, and the telomeres begin growing again.

When the engram cells were reactivated with light in the AD mice, memory of the footshock experience became retrievable and freezing behavior was restored.

The work led researchers to stumble upon another potential role for this gene, which enhances the healing power of mice when reactivated.

GFP - positive cells, indicative of reactivated latent HIV - 1, were isolated by fluorescence activated cell sorting (FACS).

If these groups of neurons are subsequently reactivated by a trigger such as a particular sight or smell, for example, the entire memory is recalled.

A student in regional management wondered how trust can be reactivated after it has eroded; a futurologist explained the limits to his predictions, which made him more trustworthy, a teacher who also took part in the discussion said.

Mice with the reactivated gene all showed better tissue healing when parts of their ears and paws were injured.

In September 2013, it was reactivated, renamed NEOWISE and assigned a new mission to assist NASA's efforts to identify the population of potentially hazardous near - Earth objects.

The results show that generation of an optimal immune response to cancer requires cooperation between two types of memory T cell — one circulating in the blood and the other resident in tissues — that can be reactivated with current immunotherapy strategies.

When a team of scientists reactivated Lin28a in a group of adult mice with shaved backs, the animals» skin and hair grew back thicker compared with control mice.

When a team of scientists reactivated Lin28a in a group of adult mice with shaved backs, the animals» skin and hair grew back thicker compared with...

Both memory T cells subtypes can be reactivated with current immunotherapy treatments, and reactivation of both requires DC1 dendritic cells.

While antiretroviral drugs are generally successful in controlling the viral load in infected individuals, preventing the progression to acquired immunodeficiency syndrome (AIDS), some viruses remain hidden for years and can be reactivated if patients stop their treatment.

The new work reveals that at least one form of long - term memory — that of fearful experiences — seems to become fragile when reactivated.

In September 2013, the WISE spacecraft was reactivated, renamed NEOWISE and assigned a new mission to assist NASA's efforts to identify the population of potentially hazardous near - Earth objects.

In patients with weakened immune systems, however, CMV can become reactivated and can cause life - threatening pneumonia, among other symptoms.

The protein is normally active in fetal tissue and switched off in adults, but it is reactivated in some cancer cells.

«It is known from previous studies in animals that the active neural pattern during a certain experience is reactivated once this experience ends, so the idea was to observe in a group of volunteers what happened at the brain level when a certain episode ended,» explains researcher Ignacio Soles.

When a latently infected cell is reactivated, the cell begins to produce HIV again.

As a result, the cells would start to become partially reactivated, growing rapidly and beginning to resemble cancer cells.

«This study revealed key regulatory principles that explain how the helicase activity is initially suppressed and then becomes reactivated to begin its work splitting the DNA.»

Early learning, says Eric Knudsen, generates the formation of neural connections that can be reactivated in adulthood.

The team notes that eIF2α becomes reactivated after a certain amount of time through pathways that guanabenz does not act upon, so eventually the stress response mechanism will shut down regardless of treatment.

The «kick - and - kill» paradigm is aimed at combining latency reversing agents (LRA) with immune effectors, such as T - cells, to wake up the virus and kill the reactivated cells.

Later, converging signals can be reactivated and sent back to the regions they came from, reconstructing a paler version of the original experience.

The results may have implications for HIV - 1 latency, in which integrated HIV - 1 remains dormant in the human genome before being reactivated at a later point.

Edgerton says the current might have reactivated damaged neurons or caused new neurons to grow across the site of the injury, or both.

Nonetheless, some ERVs may still retain the ability to become reactivated and are implicated in the development of diseases.

Also, NASA's WISE spacecraft has been reactivated and rechristened NEOWISE (link to: http://www.jpl.nasa.gov/news/news.php?release=2014-006) and could be used to characterize potential ARM targets.

Other common latent viruses could be more uncomfortable if they reactivated on a trip to Mars — chicken pox, for example, which usually returns as shingles.

A study published by Cell Press November 7th in the journal Cell has revealed that an evolutionarily conserved gene called Lin28a, which is very active in embryos but not in adults, enhances tissue repair after injury when reactivated in adult mice.

Therefore, an old scientific name was available for the «Eastern tree frog» and could be «reactivated» by Stöck.

The authors report that when the inactive halves of DAM attached to Notch and its partners rejoined, they reactivated and allowed the marking of the bound DNA in kidney cells.

In September 2013, WISE was reactivated, renamed NEOWISE and assigned a new mission to assist NASA's efforts to identify potentially hazardous near - Earth objects.

If this treatment becomes a standard practice, he says, it will reveal a lot about how different brain networks become reactivated after severe head trauma.

The observations were carried out in 2010 during the spacecraft's primary mission, before it was renamed NEOWISE and reactivated to target near - Earth objects (NEOs) in 2013.

Associated memories that are indirectly reactivated do not.

If the neurons are reactivated, the memories return.

Following over a decade of preparation, the State of Saxony - Anhalt reactivated approximately 140 hectares of floodplain here by relocating the dike in 2006.

The DNA is reactivated by adding water.

We also reactivated insulin production in human pancreatic cells from type 1 diabetes patients.»

But many questions about the link between sleep spindles and reactivated memories during sleep remained.

The Compact Muon Solenoid is one of four major detectors at the upgraded Large Hadron Collider, which was reactivated in June.

This synergy allows the drugs to be used at lower concentrations, thereby reducing toxicity, and could «increase the chances that only the virus is reactivated,» Verdin says.

They found 204 that reactivated cell proliferation, including two that affected nearly 2000 genes.

But when the researchers exposed the aging microglia to young blood through parabiosis, they were reactivated.