Not exact matches
High PI and DBI equals short lifespan MLSP despite mitochondrial Glutathione and Thioredoxin trying its best to scavenge membrane Hydroperoxides formation from
hydroxyl radical stealing hydrogen atom from unsaturated fatty acids (initiating lipid peroxidation propagation forming highly mutational
reactive aldehydes (MDA, MDA - TBARS), alkenals (4 - HNE), methylglyoxals (creating glucosepane, MDA - Lys, CML, pentosidine, CEL, furosine from Amadori).
However, up to 2 % of electrons which are transferred through the respiratory chain lead to the formation of
reactive oxygen species (ROS) in the form of superoxide anion (O 2 −), hydrogen peroxide (H2O2), and
hydroxyl radical (OH.)
While there are many types of free
radicals that can be formed, the most common in aerobic (oxygen breathing) organisms are oxygen free
radicals, often referred to as
Reactive Oxygen Species (ROS), which include superoxides,
hydroxyl anions, hydrogen peroxide and singlet oxygen.»
Instead, the culprit may be the reduced availability of highly
reactive «detergent» molecules called
hydroxyl radicals (OH) that break methane down.