Sentences with phrase «read sequences as»

Unlike other methods, which read chunks of DNA perhaps a hundred or so base pairs in length, the MinION can read sequences as long as 882,000 base pairs in length using the nanopore technology.

Not exact matches

They are reading the book of Revelation, from chapter 19, verse 11, to the end of chapter 20, a sequence of apocalyptic visions, as if they were prophecies.

In this respect, I read this book as I read any other great book: I assume that every word counts; I attend especially carefully to the sequence and the local context, in the belief that the meaning of each part is dependent partly on what comes before and after, both immediately and also remotely.

As I read this, it hits me that the Great Commission doesn't lay out a sequence.

As you read it for a second (or more) time, talk about the sequence of events and what will happen next.

Now that all three volumes of Mullin's diaries are published, it's advisable to read them in sequence — they will provide historians with as much of a valuable insight into New Labour as into the diarist himself.

In the Originating Summons marked FHC / ABJ / CS / 232/2018, the plaintiff 8 issues for determination by the court, including: Having regards to the combined provisions of sections 79,116,118,132,153,160 (1) and 178 of the 1999 constitution as amended, the constitution read together with paragraph 15 (a) of the third schedule to the same constitution, whether the 3rd defendant (Independent National Electoral Commission) is not the only institution or body constitutionally vested with the powers and vires to organized, undertake and supervised elections to the offices of the president, the vice president of the federal republic of Nigeria, the Governor and deputy governor of a state, the membership of the Senate, the House of Representatives and the House of Assembly of each state of the federation, including fixing the sequence and dates of the elections to the said offices?

As an undergraduate studying genome sciences at the National Autonomous University of Mexico, she was immediately fascinated when she read some of the early papers about sequencing Neandertal mitochondrial DNA.

Researchers have demonstrated for the first time that they can continuously read the chemical letters of DNA as it travels through a tiny pore, paving the way for a new kind of sequencing machine that decodes DNA much like an announcer reading a ticker tape.

The genome of Picea abies, one of the largest ever sequenced, appears May 22 in Nature and is one of several that have been read out recently from trees known as gymnosperms — seed - bearing plants that don't produce flowers.

Many of these repeats, including some genes, appear as back - to - back series of the same repeated sequence or as long palindromes which, like the word «racecar,» read the same forward and backward.

The third is a method implemented by Reich for reading the genetic codes of 1.2 million carefully chosen variable parts of DNA (known as single nucleotide polymorphisms) rather than having to sequence entire genomes.

In 1995, he invented a new «shotgun» technique for sequencing DNA and read the full genome of a bacterium while the establishment was still dismissing the technique as unworkable.

A study of this scope is possible thanks to innovative techniques for in vitro selection (such as mRNA display), as well as a revolutionary technology permitting massively parallel RNA sequencing (known as deep sequencing), which provides unprecedented speed and read accuracy.

«As medical researchers, if we depend only on short read sequences, there's a chink in our armor.

With this quality control missing, the entire gene sequence is read as it spools through the ribosome.

More recently, researchers have discovered that molecules can clamp onto DNA and prevent some parts of the sequence from being read, leading to genetic changes through a process that is known as epigenetics.

Reads containing only two or fewer substitutions were not classified as mutations as these likely represent sequencing artifacts.

As some reads did not extend to the 5 ′ end of the V gene, percentage identity was calculated by dividing the total identity by the length of the query sequence.

Basically, the cell's protein - making machinery reads a sequence of DNA as a sentence composed entirely of three - letter words called codons.

Recent and rapid advances in technologies that permit large - scale creation and synthesis («writing») of longer pieces of synthetic DNA, as well as the advent of extremely fast, cheap and accurate sequencing («reading») of DNA, have changed our collective thinking about the feasible size and scope of projects in many labs.

We refer interested readers to systematic comparisons of other aspects of the next - generation sequencing pipeline, for example comparisons of benchtop high - throughput sequencing technologies [56], short - read mappers [57], variant callers [58] and variant - calling pipelines as a whole [59, 60].

Frequency distribution of 17 - mer sequencing reads in the Argopecten irradians draft genome, as a function of sequencing depth.

Szabó and colleagues required a minimum of 10 sequence reads to call a gene as imprinted.

The PromethION will produce long reads on an industrial scale, meaning it will be a platform in high demand for genome assembly and transcriptomics work as well as population - scale long read sequencing.

All variant loci were simulated with single - end reads using the genome sequence to build the reads, and for coding variants we simulated splice junctions and paired - end reads as well.

Stuart Lindsay, Ph.D., Arizona State University, Tempe, Ariz. $ 550,000 (3 years) «Molecular Reading Head for Single - Molecule DNA Sequencing» Building on the concept of threading DNA through a molecular pore, this group is developing a system in which a chemical ring, acting as a reading head, is used to measure differences in friction as DNA passes through thReading Head for Single - Molecule DNA Sequencing» Building on the concept of threading DNA through a molecular pore, this group is developing a system in which a chemical ring, acting as a reading head, is used to measure differences in friction as DNA passes through threading head, is used to measure differences in friction as DNA passes through the ring.

Novel insertions of mobile elements into the sequenced genome are identified as clusters of reads that uniquely map to the reference genome with one arm and to ubiquitous sequence with the other arm.

- Scientists have long been reading the code of life — the genome — , as a sequence of letters but now researchers have also started exploring its three - dimensional organisation.

The larger number of reads per sequencing run from the infected library likely reflects the timing of the reads, as two of the three infected runs occurred after an upgrade in the capacity of the core facility.

Yet those who produce next - gen sequencing data are rapidly adopting this universal short read data format as the de facto standard.

Start by marking «The $ 1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine» as Want to Read:

SNP analysis of deep sequencing reads corresponding to the XMRV genomes of 22Rv1 (A) and LNCaP (B), as well as the mitochondrial genomes of these two cell lines (C) was performed.

All sequence reads were aligned to (1) plasmid sequences available in the NCBI RefSeq database (2138 sequences) and (2) sequences in GenBank nucleotide database annotated as plasmids (\ organism feature = «plasmid»)(9815 sequences).

A read was annotated as a resistance gene according to its best BLAST hit (blastx or tblastx) if (1) the hit had an amino acid sequence similarity above a given threshold and (2) if the alignment was at least 25 amino acids.

A read was annotated as an insertion sequence according to the best BLAST hit if (1) the hit had a sequence similarity above 80 % and (2) if the alignment was at least 50 bases.

Compared with short reads, the assemblies obtained from long - read sequencing platforms have much higher contig continuity and genome completeness as long fragments are able to extend paths into problematic or repetitive regions.

Short - read, high - throughput sequencing technology can not identify the chromosomal position of repetitive insertion sequences that typically flank horizontally acquired genes such as bacterial virulence genes and antibiotic resistance genes.

Reads with a significant hit to the qnr PSSM and that aligned with at least 25 amino acids with 90 % sequence similarity to a known qnr gene were annotated as known.

Genome sequencing has become a powerful tool for studying emerging infectious diseases; however, genome sequencing directly from clinical samples without isolation remains challenging for viruses such as Zika, where metagenomic sequencing methods may generate insufficient numbers of viral reads.

Long - read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base - pairs and maximum lengths reaching 100,000 base - pairs.

The organizers of the project, called GP - write (for work in model organisms and plants) or sometimes HGP - write (for work in human cell lines), envision it as a successor to the Human Genome Project (retroactively termed HGP - read), which 25 years ago promoted rapid advances in DNA sequencing technology.

This analysis was limited to sequence reads that mapped to the targeted chromosome X and Y SNPs with a mapping quality score of at least 37, where clusters of duplicate reads (as identified by orientation, and start and end position) were represented by the read with the highest sequence quality.

Once in a while, you'll see story sequences that I can imagine would be much more entertaining if they had voices or cool effects but instead they play like short silent films as if you're reading a comic book with no text.

The film plays like an Alien knockoff, where unfortunately its many heart - pounding and genuinely gory sequences are diminished by goofy moments that don't work, such as Jake Gyllenhaal (playing loner space vet and medic Dr. David Jordan) solemnly reading parts of Goodnight Moon.

From a whiz - bang opening sequence where space folds in on itself as combatants hurl magical fire at on another, to the charismatic, ahem, marvel that is Benedict Cumberbatch in the title role, this action film is... Read More»

At a climactic concert at a party, rows of listeners can be seen gliding off in separate directions as if on separate mind journeys, and in a much earlier surreal sequence featuring newsreel war footage in a cafe, the narrator, reading a letter, can be seen rising with his chair like a film director seated on a crane, all the way to the top of the room, where he encounters his own childhood self running a projector — an image that might be traced, like much else, to one of Proust's extended descriptive passages.

She is beautifully matched by Woody Harrelson, as the exasperated but grounded town sheriff; his character benefits from an extraordinary sequence involving the writing and reading of letters, which might not sound stirring but very much is.

It isn't nearly as good as Casino Royale, but it isn't nearly as bad as some of the reviews I read suggested - Marc Forster was a bizarre choice of director and the way he edits the big action sequences is extremely frustrating, but it's still very watchable and better than any of the Brosnan - era efforts.

But, as acted by Harris, Ben's breathtaking ability to sow chaos and cause trouble commands our attention, especially in a sequence where the trio visits Ben's wary brother Dean (Bruce Greenwood) and his aura - reading wife, Sarah (Wendy Crewson), a couple who were like parents to Matt.