This process implies a partial cell depolarization and the acquisition of a motile phenotype that involves
rearrangements of the actin cytoskeleton.
Not exact matches
Given their in vivo role in pathogenicity, and based on the yeast two - hybrid interaction data, these results point to the importance
of these pathogen proteins in modulating host ubiquitination pathways, phagosomal escape, and
actin - cytoskeleton
rearrangement processes.
The Wiskott - Aldrich syndrome protein regulates nuclear translocation
of NFAT2 and NF - $ ąppa $ B (RelA) independently
of its role in filamentous
actin polymerization and
actin cytoskeletal
rearrangement.
Defects in nuclear
actin polymerization and myosin motor function result in heterochromatin repair defects and widespread chromosome
rearrangements, revealing the importance
of the relocalization pathway in genome integrity.