One
reason vaccines using weakened flu virus are not used in the elderly is that they have been exposed to many strains of flu virus over the years and have more antibodies in the nasal tract, which can inhibit the weakened flu virus from infecting and stimulating the immune response necessary to protect against the virus.
Not exact matches
The
reason the oral vaccination is
used in the
vaccine campaign is it provides intestinal immunity that is so crucial in stopping the person - to - person transmission spread in settings where you might have a high transmission rate of the virus — like in tropical areas or areas with suboptimal sanitation.
Kieny said that for
reasons that aren't fully understood,
vaccine companies that
use eggs to grow
vaccine viruses get yields of only 25 % to 50 % of those obtained during the production of seasonal
vaccine.
For that
reason, he adds, «it would be disappointing to me if these kinds of forecasts got
used to make critical decisions for
vaccine X versus
vaccine Y.»
Influenza remains a major health problem in the United States, resulting each year in an estimated 36,000 deaths and 200,000 hospitalizations.4 Those who have been shown to be at high risk for the complications of influenza infection are children 6 to 23 months of age; healthy persons 65 years of age or older; adults and children with chronic diseases, including asthma, heart and lung disease, and diabetes; residents of nursing homes and other long - term care facilities; and pregnant women.4 It is for this
reason that the Centers for Disease Control and Prevention (CDC) has recommended that these groups, together with health care workers and others with direct patient - care responsibilities, should be given priority for influenza vaccination this season in the face of the current shortage.1 Other high - priority groups include children and teenagers 6 months to 18 years of age whose underlying medical condition requires the daily
use of aspirin and household members and out - of - home caregivers of infants less than 6 months old.1 Hence, in the case of
vaccine shortages resulting either from the unanticipated loss of expected supplies or from the emergence of greater - than - expected global influenza activity — such as pandemic influenza, which would prompt a greater demand for vaccination5 — the capability of extending existing
vaccine supplies by
using alternative routes of vaccination that would require smaller doses could have important public health implications.
There are veterinarians that question this protocol for legitimate
reasons, such as only one brand of
vaccine being tested and the
use of titers instead of disease challenge studies.
In an adult dog or much older puppy, the
reasons that vaccination fails to provoke immunity are usually related to the
use of improperly stored, handled, shipped, or administered
vaccines.
However, some diseases are too dangerous to allow to replicate, or for some other
reason the organism (whether virus, bacteria, or other parasite) must be killed to
use in a
vaccine.