Sentences with phrase «received drugs targeting»

A clinical benefit or improved patient outcome of three to eight months was seen in seven of the 19 patients (37 percent) who received drugs targeting this pathway.

Not exact matches

«Most HIV drugs target the virus,» said Huang, assistant professor of molecular microbiology and immunology at the Keck School of Medicine, which ranked No. 1 in National Institutes of Health funds received per principal investigator in 2016.

A new study suggests Ontario is nearing ambitious United Nations targets for ending the AIDS epidemics: By 2020, 90 per cent of all people living with HIV should know their HIV status, 90 per cent of all people diagnosed with HIV are receiving sustained antiretroviral drug therapy and 90 per cent of people on ART have a very low or undetectable levels of the virus.

In their report that has received advance online publication in Nature Nanotechnology, a research team based at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) describes how a nanomedicine that combines photodynamic therapy — the use of light to trigger a chemical reaction — with a molecular therapy drug targeted against common treatment resistance pathways reduced a thousand-fold the dosage of the molecular therapy drug required to suppress tumor progression and metastatic outgrowth in an animal model.

«We are delighted to receive this CIRM grant that will drive our translational research from the laboratory to the clinic,» Slamon said, «and allow us to test our targeted drug in a phase I clinical trial.»

Many cancer drugs target one of the soldier proteins that have already been expressed from a gene, have received marching orders from other proteins, and are well on their way to causing problems, such as metastasis.

In fact, the mice that received the complete nanomedicine package had smaller tumors and longer lifespans than their counterparts injected with saline, nanoparticles without the drug, the drug alone, and nanoparticles with the drug but without the targeting aptamers.

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors» mutations or being enrolled in clinical trials.

Dr James Larkin, a Consultant Medical Oncologist at The Royal Marsden, London, UK, told the 2015 European Cancer Congress [1], that results from the CheckMate 067 phase III clinical trial had already shown that the combination of the two drugs, which target two different pathways that regulate the immune system, improved the progression - free survival in patients with melanoma who had not received any other treatment.

Tumours shrank in about 60 % of women who received the targeted drug, called olaparib (Lynparza), compared with 29 % of those who received chemotherapy.

This has led to a change in direction in recent years, and the tangles are now receiving more attention as a possible drug target.

Since a drug is assumed to be effective against its target human pathology and since the vast majority of deaths in the developed world are from ageing - related causes, it is inappropriate to describe something as an anti-ageing drug unless one has good reason to believe that it will appreciably extend the life expectancy of those in the developed world who receive it.

The increasing number of drugs targeting specific proteins implicated in tumourigenesis and the commercial promotion of relatively affordable genome - wide analyses has led to an increasing expectation among patients with cancer that they can now receive effective personalised treatment based on the often complex genomic signature of their tumour.

The DWI / Drug Court in Collin County targets those drivers who are at high risk of reoffending due unless they receive serious treatment and are held accountable for their crimes.