Importantly, these mice still had significant improvement in survival compared with immunized mice
receiving placebo treatment (average survival 9 d), indicating that IFN - γ continues to play an important role in mortality in enhanced HLH disease.
The other two cats
received a placebo treatment.
Not exact matches
In a late - stage study, Aimmune, a biotech immunotherapy allergy
treatment taken via pill, found that of the roughly 500 kids with peanut allergies between the ages of 4 - 17 who were part of the trial, 67 % of those who
received the
treatment were able to tolerate 600 milligrams of peanut protein (about two to four peanuts) after about a year of
treatment, while only 4 % of those who got the
placebo could tolerate that dose of peanut protein.
Results showed that significantly more participants
receiving the enhanced
placebo SMT indicated good to excellent outcomes than those
receiving standard
placebo SMT or no
treatment.
Participants were then randomized to
receive one of four
placebo - based
treatments: vasopressin, oxytocin, saline, or no
treatment.
For one thing, they point out, acupuncture studies are extremely difficult to double - blind — a methodological approach in which neither the researchers nor patients know who is
receiving the
treatment under investigation and who is
receiving the
placebo or sham.
Patients with cirrhosis were enrolled in 2 cohorts: HCV
treatment - naive or HCV
treatment - experienced; patients within each cohort were also stratified according to HCV genotype 1 subtype (1a or 1b) and randomly assigned to
receive weight - based ribavirin (1,000 - 1,200 mg / d) or matching
placebo.
The well - known «
placebo effect» is a phenomenon whereby a patient's condition improves or a patient experiences side effects despite having
received a «fake»
treatment.
While 35 per cent of the patients who had not
received any
treatment reported an improvement, 59 per cent of the
placebo group felt better.
Within one hour of the anticipated start of anesthesia, 64 people
received the combination
treatment of Zofran (the standard therapy) plus aprepitant; the remaining 60 patients got the Zofran and a
placebo.
The patients were randomized to
treatment and control arms at a 2:1 ratio (with 345 treated and 172
receiving placebo).
The result: although the sex lives and sexual satisfaction of the women
receiving oxytocin
treatment improved significantly, the group that only
received a
placebo also had significantly improved scores.
Psoriasis patients were randomly divided into two groups, with 21 patients in the
placebo group and 22 patients
receiving the
treatment.
At the end of
treatment, the women who
received the drug reported a 21 - point reduction on a standard scale of depression symptoms, compared with about 9 points for the women on a
placebo.
Thus, so far, it has never been investigated whether individuals in clinical trials experiencing side effects from antidepressant medication, and for this reason may have guessed that they have not
received placebo, also respond more favorably to
treatment than those without side effects.
Patients taking part in the study will
receive either Genistein Aglycone or
placebo (an inactive substance that looks like the
treatment) with food, over a period of 12 months.
After a year of
treatment, in the 62 patients who
received the gene therapy, FEV1 was 3.7 % greater compared to
placebo.
Although the study began as a randomized trial that divided subjects into four
treatment groups (
placebo, deprenyl, α - tocopherol, and deprenyl / α - tocopherol), this was terminated early because positive effects of deprenyl were observed and all subjects then
received deprenyl for approximately 18 months.
Some trial participants were randomly assigned to use inhalers daily while some used them intermittently; some
received placebos and some
received no
treatment.
Four monkeys
received inosine
treatment, while four
received a
placebo.
In his new book Suggestible You, science writer Vance opens our innate mental medicine cabinet to look at the
placebo effect — or what happens when a person
receives a fake
treatment and feels better just the same.
In this study, 29 patients currently undergoing heroin - assisted
treatment were given a cortisol tablet or
placebo before
receiving a dose of heroin.
Both the researchers and participants, however, knew exactly what
treatment they were
receiving, which makes excluding a
placebo effect impossible.
The study of 826 women with previously unexplained recurrent miscarriage showed that those who
received progesterone
treatment in early pregnancy were no less likely to miscarry than those who
received a
placebo.
Both trials were halted prematurely because the results were so impressive, making it unethical not to offer the
treatment to those who had
received placebos.
In the randomized study, patients were assigned to
receive either intravenous metoprolol or a
placebo treatment at the moment of diagnosis of a myocardial infarction during ambulance transit to the catheterization laboratory.
Changhai Ding, M.D., Ph.D., of the University of Tasmania, Hobart, Tasmania, Australia, and colleagues randomly assigned 413 patients with symptomatic knee osteoarthritis and low 25 - hydroxyvitamin D to
receive monthly
treatment with oral vitamin D3 (50,000 IU; n = 209) or an identical
placebo (n = 204) for 2 years.
A few weeks later the rats that
received the drug showed improvements in walking and urinating while the
placebo treatments had no effect.
They then
received two weeks of
placebo pill
treatment — but during one of those weeks, each was told they were taking a substance that is believed to activate internal mechanisms and may have antidepressant properties.
He notes that the
placebo effect in the study came not only from participants» belief that they were
receiving a real drug, but also from the sheer impact of being in a
treatment environment.
While second - stage results showed no significant differences between participants continuing to
receive weekly doses of the active drug, those
receiving biweekly doses and those shifted to
placebo, Kimball notes that, since it is typical for the severity of HS symptoms to increase and decrease and because the study protocol required
treatment discontinuation for participants whose symptoms stopped responding to the drug, larger scale studies will be required to better define the ideal length and frequency of
treatment.
In the randomized, blinded study, half of the participants
received the
treatment while half
received a
placebo.
When participants
received the
treatment, which was taken by mouth, their cramps were three times less intense than when they
received the
placebo.
The randomized double - blind trial included a total of 138 heavy drinkers, approximately half of whom
received 12 weeks of
treatment with topiramate at a maximal dosage of 200 mg / day and half of whom
received a
placebo.
The other two groups
received a
placebo or no
treatment.
Then the 198 men in the first group
received daily
treatment for four months with either a
placebo (dummy) gel or one of four doses of testosterone gel (AndroGel, AbbVie), ranging from low to high (1.25 to 10 grams).
Members of the apalutamide group who continued to benefit from the drug were able to continue
treatment, and members of the
placebo group could begin
receiving apalutamide on an open - label basis.
In many trials, some participants are randomly assigned to the «control» group and
receive an inactive «
placebo»
treatment or a standard intervention currently in use; sometimes the control subjects are later given a chance to try the experimental
treatment.
A total of 168 participants (85 in active
treatment group; 83
receiving placebo) completed the MRI section of the trial.
Effectiveness will be determined by comparing overall survival and disease - free survival between the participants that
receive nivolumab and those that
receive placebo (dummy
treatment, one that looks like nivolumab but contains no active study drug) following surgery.
A randomized trial is a type of clinical trial in which patients are assigned to groups on a random basis where they
receive either the new experimental
treatment or the established standard of care (or a
placebo).
In some trials, not all participants
receive the test
treatment, some
receive an existing
treatment or a
placebo, in order to make a comparison.
The children who
received the double
treatment were desensitized to their food allergies faster than those taking the
placebo and had fewer digestive and breathing issues, according to the researchers.
The children
received omalizumab or a
placebo for eight weeks before starting immunotherapy and for eight weeks during combination
treatment with immunotherapy for two to five trigger foods.
The study participants were randomly assigned to
receive the combined allergy
treatment or a
placebo.
The study looked at the effect of dietary supplementation using 2,000 international units of nonprescription vitamin E daily in a large group of elderly Alzheimer's patients and compared their results over an average of around two years to similar patients who
received a
placebo, a pharmaceutical marketed as a «
treatment» for Alzheimer's disease (memantine), or a combination of memantine along with vitamin E.
Others were given
placebos while some
received no
treatment.
Individuals in remission were allocated randomly to 1 of 3 groups of
treatment: 28 continued to take their meds; 30 gradually had their replaced meds with
placebo; and 26 had their meds tapered and then
received cognitive behavioral therapy.
Peanut skin prick tests also revealed smaller wheals in study participants who had
received treatment compared to those
receiving a
placebo.
Despite that, reviews of studies have found the positive effects of homeopathic
treatment for certain conditions — including acute diarrhea, flu, and allergies — can not be explained by a
placebo effect alone (the
placebo effect is when people get better because they are
receiving some pill, even if that is a neutral «sugar pill»).