Accessing data from the National Cardiovascular Disease Registry Practice Innovation and Clinical Excellence (PINNACLE) Registry, researchers examined a nationwide sample of 68,808 patients
receiving aspirin for primary cardiovascular disease prevention.
The study found nearly 12 percent of the patients
receiving aspirin for primary prevention were receiving it inappropriately.
Researchers identified patients from 119 practices who were prescribed aspirin between January 2008 and June 2013, excluding patients
receiving aspirin as a secondary prevention due to history of cardiovascular disease such as myocardial infarction, prior stroke, and atrial fibrillation.
Patients inappropriately
receiving aspirin were, on average, 16 years younger than those
receiving aspirin appropriately.
Once again, members of one group
received aspirin to lower fever.
Not exact matches
One group
received antipyretics (fever reducers, such as
aspirin)-- typical at many hospitals.
The continuation stratum
received 100 mg
aspirin or placebo for seven days and then resumed their previous
aspirin regimen.
All patients
received placebo or 200 mg
aspirin just before surgery.
After excluding patients with liver cancer before the follow ‐ up index dates, 1,553 patients who had continuously
received daily
aspirin for at least 90 days were randomly matched 1:4 with 6,212 patients who had never
received anti platelet therapy by means of propensity scores consisting of baseline characteristics, the index date and nucleos (t) ide analogue (NA) use during follow ‐ up.
Josep Rodes - Cabau, M.D., of Laval University, Quebec City, Canada, and colleagues randomly assigned 171 patients with an indication for atrial septal defect (ASD) closure and no history of migraine to
receive dual antiplatelet therapy (
aspirin + clopidogrel [the clopidogrel group], n = 84) or single antiplatelet therapy (
aspirin + placebo [the placebo group], n = 87) for 3 months following transcatheter ASD closure.
Researchers used median rate ratio to suggest that between two «identical» patients treated at two random practices, one patient was 63 percent more likely to be prescribed
aspirin inappropriately than a similar patients due to the practice where they
receive care.
«All patients suffering from blockage of an artery in the heart or brain should
receive 325 mg regular
aspirin promptly and daily
aspirin thereafter to reduce their death rate as well as subsequent heart attacks and strokes,» said Hennekens.
Tell your doctor if you have
received any other botulinum toxin product in the last 4 months; have
received injections of botulinum toxin such as Myobloc ®, Dysport ®, or Xeomin ® in the past (tell your doctor exactly which product you
received); have recently
received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take
aspirin - like products or blood thinners.
Patients
receiving concomitant
aspirin had annual rates of any major bleeding of 3.07 % (2.70 - 3.44) and thromboembolism of 4.90 % (4.43 - 5.37), and those with renal failure were at higher risk of intracranial bleeding (hazard ratio, 2.25; 95 % CI, 1.32 - 3.82).
A population - based, case - control study27 confirmed the high risk of upper gastrointestinal tract bleeding in patients
receiving warfarin in combination with
aspirin and / or clopidogrel bisulfate.
The baseline data showed overrepresentation of cardiovascular disease in the
aspirin group compared with the group
receiving only warfarin, and our findings of a high incidence of thromboembolic events in the
aspirin group are, therefore, as expected.
One hundred percent of dogs
receiving only a single dose of
aspirin bleed into their gastrointestinal tracts.
Your dog or cat's bleeding time can be extended when it has
received NSAIDs (such as
aspirin, Rimadyl, Deramaxx, Previcox, etc.)- particularly if the pet already has other health issues that delay its blood coagulation or if it has genetic bleeding tendencies (such as mild von Wilibrand disease [vWD]-RRB-.
Individuals below 19 years of age with a rare and fatal disease of Reye's syndrome, and
receiving «long - term»
aspirin therapy