Sentences with phrase «receiving lower doses»

Knocking out a gene that muffles the painkilling signal of morphine yields animals that can tolerate pain for longer periods of time, even while receiving lower doses of the drug, reports a team of...

Participants who took the largest 10 - mg dose showed less decline on one of two memory tests than those receiving lower doses, or the placebo.

These antianxiety drugs «are known to be safe, and we are using them at very low levels here,» study author Scheuer notes, adding he is not concerned about human patients receiving low doses of antianxiety drugs off - label.

They found that two of the groups, which had received the lowest doses of the oral agent, were significantly worse off than the controls, which received no treatment, Franco says.

Volunteers received a low dose of Escherichia coli (E. coli) endotoxin to induce controlled inflammation and received either lexaptepid or placebo 30 minutes later.

But if children near Chernobyl received a lower dose, it could have damaged their DNA without killing the cells.

Preliminary evidence suggested that the vaccine wards off disease; none of the patients who received the vaccine developed influenza in the winter after they were vaccinated, compared to two in a group who received a lower dose, and seven in the placebo group, the team reports today in the Journal of the American Medical Association.

Patients who received the highest radiation doses had a risk of stomach cancer nearly threefold greater than patients who received the lowest doses.

But volunteers who received the high dose of the vaccine made more antibodies against the Zaire - Guinea strain than did those who received a lower dose.

Volunteers who received a high dose of the vaccine had, on average, higher antibody levels than people who received a lower dose.

Two other types were isolated from two animals which had received a low dose stationary phase aerosol infection.

In a trial like this, formally called a multiple ascending dose study, the first participants receive a low dose and then participants who join later receive higher doses of the drug.

The first patients in the study received lower doses.

Researchers at Oregon Health and Science University placed 68 patients suffering from SAD into three groups, two of which received low doses of melatonin.

Sixty - four dogs received a standard dose of pimobendan (0.20 — 0.48 mg / kg every 12 hr (q12hr)-RRB-, 49 dogs received a low dose of pimobendan (0.05 — 0.19 mg / kg q12hr) and 84 dogs received conventional therapy alone.

In the pilot study, 30 large, middle - aged dogs will be involved — half receiving low doses of rapamycin, half receiving placebos.

Not exact matches

In 2006, scientists evaluated the effects of vitamin D on the mental health of 80 elderly patients and found those with the lowest levels of vitamin D were 11 times more prone to be depressed than those who received healthy doses.

Many of the epidural side effects mentioned below are not improved with low - dose or walking epidurals, because women using these techniques may still receive a substantial total dose of local anesthetic, especially when continuous infusions and / or patient - controlled boluses (single large doses) are used.34 The addition of opiate drugs in epidurals or CSEs can create further risks for the mother, such as pruritus (itching) and respiratory depression (see below).

Women scheduled for labor induction between 32 and 42 weeks and with unfavorable cervices (modified Bishop score 6 or lower) were randomized to receive oral misoprostol every 4 hours, up to four doses, with or without isosorbide mononitrate every 6 hours, up to two doses.

A growing body of evidence indicates that receiving a mother's own milk, especially in high doses very soon after birth reduces the risk of acquiring very costly conditions in very low birthweight infants including sepsis, chronic lung disease and, especially, necrotizing enterocolitis, a devastating disease that affects mostly the intestine of premature infants.

Dr. Rassool says that a clinical trial is planned to test whether low doses of a DNMT inhibitor, decitabine, and an investigational PARP inhibitor, talazoparib, can be safely combined and whether this therapy shows efficacy for AML patients, especially those who can not receive intensive chemotherapy, whose leukemia is resistant to treatment, or who have experienced a relapse after treatment.

At the end of the trial, those who received the high - dose vaccine scored an average of 39 percent lower on symptoms and medication use than did those who got the dummy shots.

Veterans prescribed higher doses of benzodiazepines while concurrently receiving opioids were at greater risk of overdose death than those on lower doses of benzodiazepines.

On the other hand, NPD1 = PD1 can relieve neuropathic pain at very low doses and, more importantly, mice receiving the treatment did not show signs of physical dependence or enhanced tolerance toward the lipid compound.

So, to examine a potential dose effect, they grouped the four patients who had received low RAI doses for DTC with the five who had received low RAI doses for Graves» disease.

One group was given a low dose of the drug, a second group received a higher dose and the third, a placebo.

A few hundred volunteers received low to medium doses of LSD at Edgewood, compared to the amounts used recreationally by millions of young civilians during the same period.

A growing body of evidence indicates that receiving a mother's own milk, especially in high doses very soon after birth reduces the risk of acquiring very costly conditions in very low birthweight infants including sepsis, chronic lung disease and, especially, necrotizing enterocolitis, a devastating disease that affects mostly the intestine of premature infants.

Parents also had low awareness of the three - dose regimen, poor recall about whether their child had received all three doses, and little understanding of why boys should be vaccinated, the study found.

Influenza vaccine coverage overall is low among young children and those in need of two doses in a given season are at particular risk, with less than half of those who receive the first dose returning to receive the second needed doses.

African American and Latino patients of doctors with «high bias» received exactly the same intensification of treatment in response to high blood pressure — upping the dose or adding a new medication — as patients of a doctor with «low bias.»

Among patients who do receive opioids, the new Consensus Statement recommends prescribing the lowest effective doses for the shortest duration possible, based on recent studies that demonstrate opioids» risks increase with dosage.

Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have uncovered new clues about the risk of cancer from low - dose radiation, which in this research they define as equivalent to 100 millisieverts or roughly the dose received from ten full - body CT scans.

Then the 198 men in the first group received daily treatment for four months with either a placebo (dummy) gel or one of four doses of testosterone gel (AndroGel, AbbVie), ranging from low to high (1.25 to 10 grams).

«A subgroup analysis that combines data from children in both the single - and multiple - dose studies demonstrated a mean 5 point increase in muscle function score in children who received at least 9 mg of ISIS - SMNRx between the ages of two and 10 who did not have severe scoliosis or baseline HFMSE scores at the extreme low or high ends of the scale.

Fifty - three patients received standard - dose and 52 patients received low - dose CNIs (80 % of standard); 51 patients in the control group received anti — IL - 2 receptor antibody plus standard - dose CNIs.

Prior to transfusion, patients receive low - dose chemotherapy with the drug busulfan.

Two groups of 12 subjects each were randomized to receive either a low (15 µg) or a high (75 µg) dose of the vaccine, one injection monthly for the first 4 months, and were monitored for a total of one year; 8 subjects serving as untreated controls and treated with best usual care.

As anticipated, those who received a high dose were reported to have higher memory function scores than those who got a low dose.

An animal study published in the September 2011 «Journal of Ethnopharmacology» found that doses of 20 milligrams per kilogram body weight per day for 30 days resulted in lower blood sugar, insulin and cholesterol levels compared to a control group that did not receive cilantro seed extract.

Heroin addicts treated with a single daily dose of methadone and nonaddicts receiving continuous intrathecal opioids quickly develop low luteinizing hormone and total testosterone levels.

In 2006, scientists evaluated the effects of vitamin D on the mental health of 80 elderly patients and found those with the lowest levels of vitamin D were 11 times more prone to be depressed than those who received healthy doses.3

We generally recommend a weekly injection schedule with doses much, much lower than a man would receive.

A second group of 377 patients suffering from Hashimoto's thyroiditis was treated with a non-suppressive hormone medication, a suppressive hormone administration, a combination of a non-suppressive hormone therapy with low dose iodide (50 - 150 micrograms / day), mere iodide in doses of 200 micrograms / day, or received no therapy.

The tablets are designed to release the 5 mg dose slowly throughout the night so that you're receiving a consistent and low dose to put you to sleep gently and keep you asleep longer.

Men who receive large total doses because of many treatments with RAI may have lower sperm counts or, rarely, become infertile.

The average insulin dose was 12 % lower than the other group that received a non-sweet commercial tea.

Beth Overley, a veterinary oncologist in Langhorne, PA, explains that because vets hope to extend life for only 6 months to a few years, they use lower doses of chemo and radiation than humans receive.

To do this, we use much lower doses of chemotherapy than humans receive.

Your pet will receive high doses for the first 1 - 2 weeks, and then the dose will be lowered under the direction of your veterinarian.