Sentences with phrase «recent years model»

Insights from model organisms have long helped scientists understand the biology behind such genetic diseases, but in recent years model organism researchers have become even more directly involved in diagnosing the millions of people affected — and in searching for treatments.

Not exact matches

While the term has become popular in recent years, it's built around the idea of subscription - models, which has been around since long before the digital age.
Releasing their recent findings, LinkedIn found that only 12 % of professionals are willing to pay for digital content in the next year, despite the trend for publishers to use subscription business models and content paywalls.
The crux of its argument is that in recent years, Apple has lagged behind, debuting «innovations» on the iPhone that Samsung already featured on Galaxy models that were released first.
The shift has squeezed margins in recent years because the cloud business model is based on subscriptions which take longer to pay off — in contrast to one - off, up - front software license payments that was the thrust of its business for decades.
A recent Accenture Trend Report noted that 81 percent of executives say platform - based business models will be core to their growth strategy within three years.
Mattel (mat), which has been greatly diversifying its Barbie range in recent years, earlier this week announced a series of dolls representing good role models for girls.
While some skepticism arose over the search fund model in its early days, continued success (and average returns north of 30 percent) has led to significant growth of the category in recent years.
«I would say the accounting at GE has not been a model at all in recent years, but you can make mistakes,» said Buffett, who exited his stake in GE last year.
Straight size vs. plus size: it's a conversation that has frothed to the forefront of the modeling industry in recent years, but according to filmmaker Jenny McQuaile, it misses the point.
Yet recent visitors to General Motors dealerships might feel a sense of déjà vu: they are offering 0 % interest loans on some models, and one can finance a $ 28,000 Chevy Malibu for seven years at 1.99 %.
So far, the carriers» deals both on the X and on the 8 models are not nearly as generous as last year, when most offered a free iPhone 7 with the trade in of another recent model iPhone.
Economics is supposed to provide mathematical modelling of human behaviour, but the apparent divergence of economic theory from reality in recent years has become a burr under Orrell's saddle.
The value - add model has been an increasingly popular and lucrative one in many regions of the country in recent years, says Jack Mulcahy, a credit risk analyst at CoStar, a commercial real estate market research firm.
It's been four years since a model made the first major allegation of sexual misconduct against Richardson, and five days since the most recent.
Several Thai politicians who attended the Boao Forum for Asia, a kind of China - centered version of the World Economic Forum in Davos, noted that, in recent years, some of the discussions at Boao had shifted from a kind of general talk of globalization and its impact in Asia to more specific conversations about some of the failings of Western economic models exposed by the global economic crisis, and whether China's type of development might be less prone to such risks.
In contrast, bond market exposure (in the form of yield curve and spread risk) has played a relatively minor role in driving convertible bond risk and return in the recent past and seems likely to play a minor role in the year ahead, based on our model.
In recent years, analysts have increasingly assumed, in their models, that deficits resulting from tax cuts are ultimately paid for by tax increases or spending cuts several decades in the future.
This is sometimes called the «Fed model» since it appeared in one of the Fed's reports in recent years.
Canada's image on the world stage has grown considerably in recent years and our actions in specific aspects of economic policy are considered by many non-Canadians to be a role model for other nations.
Asset managers have been using MSCI risk models for years — the vendor has been in this game for four decades — and according to the most recent P&I rankings, 97 of the top 100 largest money managers are MSCI clients.
Roper and other consumer advocates argue that conflicted advice is deeply engrained in the brokerage business model, echoing the concerns outlined in a recent leaked White House policy memo in which officials concluded that «the current regulatory environment creates perverse incentives that ultimately cost investors billions of dollars a year» in the form of unnecessary rollovers of 401 (k) plans into costly IRAs, and «excessive churning (repeated buying and selling) of retirement assets.»
In recent years, asset managers, pension funds and investment companies have been burned too many times using traditional investment analysis that identified investment opportunities that were, based on the models, rock solid.
Recent estimates produced with models similar to JCT's have found the tax bills may increase the growth rate by 0.03 to 0.09 percentage points per year, producing as much as $ 200 billion of dynamic feedback.
Per a recent article in the Financial Times, The Penn Wharton Budget Model expects at most a 0.1 % uplift to annual GDP growth over the next 10 years.
In a recent interview with Karen Webster, Greenfield explained how Candid leverages a direct eCommerce business model as well as other technologies, many of which were not available even three years ago, to provide an expensive service at an inexpensive rate and in a modern, convenient fashion that meets the expectations and needs of today's consumers.
«We are convinced that «quant» funds», which have attracted hundreds of billions of dollars in the last few years and a significant portion of which use leverage, and whose models and various strategies are largely based on price action and correlations extracted from the reasonably - recent past when volatility has been low (largely of their own making), have contributed mightily to the illusion that market risk is low.
but considering: a) his divorce * preceded * this crisis of faith (& therein career, education, etc.) b) he is marketing this paradigm shift rather than simply experiencing it c) he appears to be reciprocating the recent rash of «i followed the bible for a year» model of book - writing & simply applying it to atheism
Although the inadequacies of these models have long been lamented in some circles, and increasingly so in recent years, my point is that the problems are perpetuated by the lack of clearly formulated models and images of power.
In recent years, however, many have challenged the decision - point model of morality.
In recent years that model has come under increasing criticism.
This is the most positive model of recent years.
Although he recognizes that the shift in recent years from strict, no - aid separationism to an equal - treatment - of - religion model has produced some good results (upholding school vouchers, for example), he insists that neutrality and equality are not enough.
Some models have been worn thin by premature exposure to children, so that their use at a later age is ineffective; but chiefly we have the problem of vast cultural changes in recent years.
This is a trend that goes hand in hand with the church's general infatuation with corporate business models — as evidenced in recent years by the invention of a new breed of minister: the executive pastor armed with an M.Div.
In recent years we have been fascinated by the models of health defined by Freud, by Eastern religion, by technology, by philosophy.
We have in recent years witnessed a number of new theoretical schemes — or attempts to revive old schemes in which collective, behavioral, observable variables predominate: ecological theories, economistic models, market metaphors, notions of moral order and moral economy, and cybernetic and behaviorist approaches, to name a few.
Leaf has done an incredible job of becoming a positive role model in recent years.
30 year old Portuguese international Ronaldo split from long term girlfriend Shayk in recent weeks and playboy model Chavez has now come out and claimed that she had an affair with the Ballon d'Or winner.
Time for some brutal honesty... this team, as it stands, is in no better position to compete next season than they were 12 months ago, minus the fact that some fans have been easily snowed by the acquisition of Lacazette, the free transfer LB and the release of Sanogo... if you look at the facts carefully you will see a team that still has far more questions than answers... to better show what I mean by this statement I will briefly discuss the current state of affairs on a position - by - position basis... in goal we have 4 potential candidates, but in reality we have only 1 option with any real future and somehow he's the only one we have actively tried to get rid of for years because he and his father were a little too involved on social media and he got caught smoking (funny how people still defend Wiltshire under the same and far worse circumstances)... you would think we would want to keep any goaltender that Juventus had interest in, as they seem to have a pretty good history when it comes to that position... as far as the defenders on our current roster there are only a few individuals whom have the skill and / or youth worthy of our time and / or investment, as such we should get rid of anyone who doesn't meet those simple requirements, which means we should get rid of DeBouchy, Gibbs, Gabriel, Mertz and loan out Chambers to see if last seasons foray with Middlesborough was an anomaly or a prediction of things to come... some fans have lamented wildly about the return of Mertz to the starting lineup due to his FA Cup performance but these sort of pie in the sky meanderings are indicative of what's wrong with this club and it's wishy - washy fan - base... in addition to these moves the club should aggressively pursue the acquisition of dominant and mobile CB to stabilize an all too fragile defensive group that has self - destructed on numerous occasions over the past 5 seasons... moving forward and building on our need to re-establish our once dominant presence throughout the middle of the park we need to target a CDM then do whatever it takes to get that player into the fold without any of the usual nickel and diming we have become famous for (this kind of ruthless haggling has cost us numerous special players and certainly can't help make the player in question feel good about the way their future potential employer feels about them)... in order for us to become dominant again we need to be strong up the middle again from Goalkeeper to CB to DM to ACM to striker, like we did in our most glorious years before and during Wenger's reign... with this in mind, if we want Ozil to be that dominant attacking midfielder we can't keep leaving him exposed to constant ridicule about his lack of defensive prowess and provide him with the proper players in the final third... he was never a good defensive player in Real or with the German National squad and they certainly didn't suffer as a result of his presence on the pitch... as for the rest of the midfield the blame falls squarely in the hands of Wenger and Gazidis, the fact that Ramsey, Ox, Sanchez and even Ozil were allowed to regularly start when none of the aforementioned had more than a year left under contract is criminal for a club of this size and financial might... the fact that we could find money for Walcott and Xhaka, who weren't even guaranteed starters, means that our whole business model needs a complete overhaul... for me it's time to get rid of some serious deadweight, even if it means selling them below what you believe their market value is just to simply right this ship and change the stagnant culture that currently exists... this means saying goodbye to Wiltshire, Elneny, Carzola, Walcott and Ramsey... everyone, minus Elneny, have spent just as much time on the training table as on the field of play, which would be manageable if they weren't so inconsistent from a performance standpoint (excluding Carzola, who is like the recent version of Rosicky — too bad, both will be deeply missed)... in their places we need to bring in some proven performers with no history of injuries... up front, although I do like the possibilities that a player like Lacazette presents, the fact that we had to wait so many years to acquire some true quality at the striker position falls once again squarely at the feet of Wenger... this issue highlights the ultimate scam being perpetrated by this club since the arrival of Kroenke: pretend your a small market club when it comes to making purchases but milk your fans like a big market club when it comes to ticket prices and merchandising... I believe the reason why Wenger hasn't pursued someone of Henry's quality, minus a fairly inexpensive RVP, was that he knew that they would demand players of a similar ilk to be brought on board and that wasn't possible when the business model was that of a «selling» club... does it really make sense that we could only make a cheeky bid for Suarez, or that we couldn't get Higuain over the line when he was being offered up for half the price he eventually went to Juve for, or that we've only paid any interest to strikers who were clearly not going to press their current teams to let them go to Arsenal like Benzema or Cavani... just part of the facade that finally came crashing down when Sanchez finally called their bluff... the fact remains that no one wants to win more than Sanchez, including Wenger, and although I don't agree with everything that he has done off the field, I would much rather have Alexis front and center than a manager who has clearly bought into the Kroenke model in large part due to the fact that his enormous ego suggests that only he could accomplish great things without breaking the bank... unfortunately that isn't possible anymore as the game has changed quite dramatically in the last 15 years, which has left a largely complacent and complicit Wenger on the outside looking in... so don't blame those players who demanded more and were left wanting... don't blame those fans who have tried desperately to raise awareness for several years when cracks began to appear... place the blame at the feet of those who were well aware all along of the potential pitfalls of just such a plan but continued to follow it even when it was no longer a financial necessity, like it ever really was...
Connelly's model, which takes into consideration recent history, returning production, and recruiting, has Ohio State (No. 1), Notre Dame (No. 7), Penn State (No. 8), Michigan State (No. 11) and Wisconsin (No. 12)-- all teams Michigan will face next year.
I believe it's time for a change of manager simply because Arsene's style has gone stale in recent years, but I have no interest in changing the business model.
While TVs have been constantly getting slimmer over the years, Panasonic's most recent model takes the cake.
In recent years, the word «transparency» has been thrown around in political arenas, bureaucratic agencies, and business model practices.
I would like to see adoption in the country start to model the Australian way of handling adoption, which has reduced its numbers drastically in recent years.
Only a few models have been manufactured in recent years, but some of these car seats may still be found at yard sales.
This recent model has taken advantage of the technology of the last few years, melding it into the high quality design that Chicco ™ is known for — especially amongst parents.
Studies of the Nurse Family Partnership model followed children to 6 years and found significant program effects on language and cognitive functioning as well as fewer behaviour problems in a randomized controlled trial study.24 In addition, more recent evaluations of Healthy Families America have shown small, but favourable effects on young children's development.25, 26
Meta - analyses of this expanded research base confirm the model's impacts on a range of risk and protective factors associated with child maltreatment.7, 8,9 In addition, all of the major home visitation models in the U.S. are currently engaged in a variety of research activities, many of which are resulting in better defined models and more rigorous attention to the key issue of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up of the Early Head Start National Demonstration Project confirm the efficacy of home visitation programs with new parents.
But in recent years, Summer Infant has put more effort into their line of strollers and today they have three to choose from: the 3D Lite, an umbrella stroller, the Fuze, a more luxurious reversing - seat convertible stroller, and then the one we look at here, the Spectra, their lightweight model right in between.
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