Steroid
receptor coactivators 1 and 2 mediate fetal - to - maternal signaling that initiates parturition.
UT Southwestern biochemists studying mouse models found that the two proteins − steroid
receptor coactivators 1 and 2 (SRC - 1 and SRC - 2)-- control genes for pulmonary surfactant components that promote the initiation of labor.
Not exact matches
GT198, which is also a
coactivator of
receptors for steroid hormones such as estrogen, is normally regulated by estrogen, Ko said.
These differences suggest that adapting to exercise involves many processes, but scientists have observed that one gene in particular, peroxisome proliferator - activated
receptor - gamma
coactivator PGC - 1α, controls many of them.
Among the other genes she says play a role in thoroughbred performance are peroxisome proliferator - activated
receptor - γ
coactivator - 1 alpha (PGC - 1α), which is involved in skeletal muscle adaptation to exercise; pyruvate dehydrogenase kinase, isozyme 4 (PDK4), involved in glucose regulation, expression of which increased almost fourfold after sprints; and cytochrome c oxidase subunit 4 isoform 2 (COX 4I2), involved in respiration.
It is a required
coactivator of TGF - beta, Notch and nuclear
receptor genes.
FNDC5 expression was shown to correlate with peroxisome proliferator - activated
receptor gamma
coactivator 1 - alpha (PGC - 1α) expression levels in various developmental stages and tissues, including neurons.
Their gene expression profile revealed striking up - regulation of peroxisome proliferator - activated
receptor gamma
coactivator 1alpha (an up - regulator of mitochondrial biogenesis not normally expressed in white fat), increased uncoupling proteins - 1 and -2, and down - regulation of lipogenic enzymes.
Dissection of the LXXLL nuclear
receptor -
coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen
receptors alpha and beta
Peroxisome proliferator activated
receptor gamma
coactivator 1 alpha transcript variant B4 3ext antibody
Peroxisome proliferator activated
receptor gamma
coactivator 1 alpha transcript variant B5 NT antibody
(In more technical terms, vitamin A is said to «recruit
coactivators» that are needed for expression of vitamin D
receptors, and the form of vitamin A needed to assist with vitamin D metabolism in this situation is 9 - cis - retinoic acid.)
When fastening to the PPAR
receptor, it was discovered that Cardarine recruits the
coactivator PGC - 1 a enzyme that increases genes appearance in the energy expenditure.