al., tested the hypothesis that herbivores — and their plant diets — have evolved to have greater number of Tas2r bitter taste
receptor genes in their genomes than omnivores or carnivores.
Not exact matches
«We found that interbreeding with archaic humans — the Neanderthals and Denisovans — has influenced the genetic diversity
in present - day
genomes at three innate immunity
genes belonging to the human Toll - like -
receptor family,» says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology
in Leipzig, Germany.
Zwiebel and colleagues scanned the mosquito
genome looking for
genes similar to those that generate fruit fly odorant
receptors, proteins that project from nerve cells and initiate a biochemical cascade when they encounter certain molecules
in the air.
The researchers scoured the already deciphered mouse
genome, looking for
genes that might encode additional
receptor proteins
in its olfactory system, the sensory cells that connect the nose to the brain.
The former target, say, using
gene editing techniques to inactivate HIV
receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on
in clincial trials) is different than helping parents who both carry
genes for Huntington's Disease to have a child that is free of the disease (a change to the
genome that would be passed on to future generations and would likely not be very commonly needed).
«To fully understand the loss of olfactory
receptor genes in the ground tit, further comparisons need to be made with
genomes of closely related species inhabiting lower altitudes.»
And the third type is a translocation,
in which half of the estrogen
receptor gene is swapped for a completely unrelated
gene from a different part of the
genome.
The Amur tiger
genome was predicted to contain 20,226 protein - coding
genes and 2,935 non-coding RNAs, and was enriched
in olfactory
receptor sensitivity, amino - acid transport, and metabolic - related
genes, among others.
For instance,
in the human
genome we still see the remnants of the large olfactory
receptor gene family that gave our evolutionary ancestors a keen sense of smell, even though humans no longer rely on them.
The research team has used the full
genome to search for and confirm that
genes responsible for color
receptors are indeed absent
in owls.
Covering the entire
genome, the study discovered that a common variation
in the melatonin
receptor 1A (MTNR1A)
gene is linked to the job - related exhaustion experienced by shift workers.
Cats rely less on their sense of smell for huntings than dogs do, which is apparent from the smaller repertoire of olfactory
receptor genes in the feline
genome.
In Emory's Department of Pharmacology, the Traynelis and Yuan labs have been harvesting the vast amounts of information now available from public genome databases, to better understand how changes in the NMDA receptor genes relate to functio
In Emory's Department of Pharmacology, the Traynelis and Yuan labs have been harvesting the vast amounts of information now available from public
genome databases, to better understand how changes
in the NMDA receptor genes relate to functio
in the NMDA
receptor genes relate to function.
High - density oligonucelotide arrays were designed to target the computationally predicted 3 ′ UTRs of OR and VR
genes and probe the expression of all
receptors annotated
in an early
genome assembly [9], [31].
We find evidence of expression for all VR, and almost all OR
genes that are annotated as functional
in the reference
genome, and use the data to generate over 1100 new, multi-exonic, significantly extended
receptor gene annotations.
The olfactory (OR) and vomeronasal
receptor (VR) repertoires are collectively encoded by 1700
genes and pseudogenes
in the mouse
genome.
The octopus
genome contains around 1,800 C2H2 zinc finger transcription factors, the second largest
gene family so far discovered
in animals (olfactory
receptor genes in elephants are the largest at around 2,000).
In human populations,
genome - wide association studies have revealed associations between variants of the circadian clock — related
gene Mntr1b, which encodes melatonin
receptor 1B, fasting glucose concentrations, and the risk of type 2 diabetes (12 — 14).